@gitanguyi
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So very happy to share our preprint for the main work of both our PhDs ! Check out Rene's thread to learn about the tools we developed for #chloroplast engineering and how we use them to test a photorespiratory bypass in #Chlamydomonas !!
Very excited to share the preprint of a big chapter of my PhD, where I am corresponding & shared first author (together with @gitanguy) about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas:
Below in a 🧵:
biorxiv.org/content/10.1101/…
Tanguy Chotel retweeted
New in Nature Communications: Our study uncovers how green algae coordinate the CO₂-concentrating mechanism and photorespiration during low CO₂ acclimation. This has implications for oceanic carbon cycling. 1/4
nature.com/articles/s41467-0…
#Algae #Photosynthesis #ClimateScience
Tanguy Chotel retweeted
Happy to share our story on evolution of protein quaternary structure!
We discover an astounding variation in assembly across evolutionary timescales contrasted by strong functional conservation suggesting a significant role of non-adaptive processes nature.com/articles/s41467-0…
👇🧵
Tanguy Chotel retweeted
Lets talk about #acetyl-CoA! As central molecule in C1 metabolism, the efficiency of its assimilation determines yields. Read below about our Lcm as novel activity in the shortest O2 tolerant route to make pyruvate from acetyl-CoA while fixing #CO2!
nature.com/articles/s41467-0…
Tanguy Chotel retweeted
🚨 We're hiring!🚨
Paris Biofoundry is looking for an Application Engineer in Biological Analyses by Mass Spectrometry.🧬
📅 Start: Feb 1, 2025
📍 Location: Paris
🧪 Requirements: MSc in Biochem/Analytical Chemistry, 1-4 yrs experience
Apply now !
🔗 parisbiofoundry.org/our-job-…
Tanguy Chotel retweeted
Unique biogenesis and kinetics of hornwort Rubiscos revealed by synthetic biology systems: Molecular Plant cell.com/molecular-plant/ful… @MPlantPCom
Tanguy Chotel retweeted
Excited to share our latest preprint!
Proteomic analysis of the pyrenoid-traversing membranes of Chlamydomonas reinhardtii reveals novel components biorxiv.org/content/10.1101/…
Tanguy Chotel retweeted
Thrilled to share our latest preprint on how Chlamy acclimates to light stress under day-night cycles! We provide a genome-wide view of the central dogma, correlate changes in thylakoid membranes with the lipidome, track photodamage, quenching, and more.
doi.org/10.1101/2024.10.22.6…
Tanguy Chotel retweeted
Too dim, too bright, and just right: Systems analysis of the Chlamydomonas diurnal program upon acclimation to light stress and limitation biorxiv.org/content/10.1101/…
Tanguy Chotel retweeted
It was an amazing experience to attend the Grand Jamboree and see all the incredible ideas! We are thrilled to have won the Grand Prize. We would like to thank all the sponsors, supervisors, PIs and supporters who made this possible. Words cannot express our gratitude! @iGEM
Tanguy Chotel retweeted
Congratulations to @igemmarburg and iGEM Heidelberg for winning the Grand Prize🥳!
Tanguy Chotel retweeted
Finally, decided to post my lecture slides online. Hoping someone will find them useful🙂 manishkushwaha.net/teaching/
Tanguy Chotel retweeted
Novel enzyme starts with promiscuity. Excited to share our study that shows how #evolution recruits a single enzyme for multiple purposes, showcasing the plasticity and flexibility of #metabolism. Huge thanks to my colleagues at @erblabs & @mpi_marburg! rdcu.be/dXaqU
Tanguy Chotel retweeted
Excited to finally making the first steps turning our DynaPore project into an actual technology!
Please, support us by casting a vote for team DynaPore 🦖
From #research to #application: Our DynaPore team, @ScottAScholz, @bobelly_, @mmMarkus_Meier and Owen Jarman from @erblabs are competing at #HIWettbewerb start-up competition. 𝗩𝗼𝘁𝗲 for team DynaPore until Nov 7th, to support them in reaching the final:
hessen-ideen.de/ideen/alumni…
Tanguy Chotel retweeted
From #research to #application: Our DynaPore team, @ScottAScholz, @bobelly_, @mmMarkus_Meier and Owen Jarman from @erblabs are competing at #HIWettbewerb start-up competition. 𝗩𝗼𝘁𝗲 for team DynaPore until Nov 7th, to support them in reaching the final:
hessen-ideen.de/ideen/alumni…
Tanguy Chotel retweeted
I am so happy to be a part of the Hessen Ideas competition with our amazing team from the MPI-TM! Please take a moment to vote for our Project DynaPore 🦖
All links and some pretty team pictures in the thread below ;)
#ideenwettbewerb #HIWettbewerb
From #research to #application: Our DynaPore team, @ScottAScholz, @bobelly_, @mmMarkus_Meier and Owen Jarman from @erblabs are competing at #HIWettbewerb start-up competition. 𝗩𝗼𝘁𝗲 for team DynaPore until Nov 7th, to support them in reaching the final:
hessen-ideen.de/ideen/alumni…
Tanguy Chotel retweeted
Our paper on continuous mutagenesis in living cells using HACE is now out in @ScienceMagazine!
We now demonstrate that HACE continuously generates mutations over a 10-day period and enables targeting using dCas9 without introducing DNA nicks.
science.org/doi/10.1126/scie…
Tanguy Chotel retweeted
I am thrilled to present the Paris Biofoundry to the World. A distributed Biofoundry for high-throughout engineering of bacteria, yeast, microalgae, mammalian cells, and Cell-free systems. #biofoundry #Synbio
🧬Excited to introduce the @ParisBiofoundry uniting @Sorbonne_Univ_, @Genopole, @institut_curie and @INRAE_MICALIS. 🌍🔬
Our goal? Accelerating #innovation in #health, #sustainability, and #biotech through #bioengineering and #robotics.
Stay tuned !👉 parisbiofoundry.org
Tanguy Chotel retweeted
🧬Excited to introduce the @ParisBiofoundry uniting @Sorbonne_Univ_, @Genopole, @institut_curie and @INRAE_MICALIS. 🌍🔬
Our goal? Accelerating #innovation in #health, #sustainability, and #biotech through #bioengineering and #robotics.
Stay tuned !👉 parisbiofoundry.org
Tanguy Chotel retweeted
Congrats @james_r_barrett & co! My fave story this year: delving into nature's different approaches to condensing Rubisco into a pyrenoid 🤩 Same mechanism, different execution - and it works in land plants!! Huge implications for crop engineering
nature.com/articles/s41477-0…
Tanguy Chotel retweeted
A blueprint of the diatom pyrenoid reveals a Rubisco encapsulating protein Shell is critical for CO2 fixation. Is it essential for global NPP? Congrats to @OnyouNam,@james_r_barrett,@ItsCarolineMck,@JNB_lab + great collab with @DemulderManon,@bengeliscious.doi.org/10.1016/j.cell.2024.…