Pathologist (AP/CP) trained at @TuftsUniversity, @TuftsMedSchool. Triple Jumbo. Tweets/opinions are mine, not employers and for education.
Boston, MA
Joined January 2010
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My quality team wants me to add more to my never ending list of monitors. I will take a look. Thanks! @DrGeeONE
Hot off the press!
Quality indicators of pathology and laboratory medicine in cancer: a narrative synthesis of published literature - ecancer
#ecancer @ecancer
ecancer.org/en/journal/artic…
Muse can create and automate tumor board ppt presentations directly from your iphone using images from your photostream. I’m impressed. Try it.
Garrey Faller retweeted
Benign nodal inclusions in axillary sentinel nodes
- Endosalpingiosis
- Mammary gland inclusions
- Squamous inclusions
- Nodal nevi
Dr. Cimino-Mathews #BreastPath #PathX #Pathtwitter #USCAP
Garrey Faller retweeted
Follicular adenoma with papillary architecture🤔
In the WHO 5th edition of Endocrine & Neuroendocrine Tumors, follicular adenoma with papillary architecture (FA-PA) is now recognized as a variant of follicular adenoma.
✅ Benign, encapsulated/well-circumscribed
✅ No capsular or vascular invasion
✅ Often a solitary “hot” (hyperfunctioning) nodule, more common in women
🔬Cystic with mixed papillary & follicular growth. Nuclear features of PTC are absent.
🧬Unlike conventional follicular adenoma (RAS), FA-PA frequently shows activating TSH-receptor mutations (~70%) and occasional GNAS mutations
Dr. Scognamiglio #USCAP #PathX #pathology
Garrey Faller retweeted
busy Monday #GUpath signout🔬 today, but worth stopping and smelling the prostate bx🌹
#ABT
#alwaysbeteaching
🔬"branching" pattern Gleason 3 (mimic of pattern 4)
(I call this 3+3)
Garrey Faller retweeted
Sclerosing adenosis and fibrocystic changes can have foci of squamous metaplasia
⚠️ Pitfall: Overinterpreting this as carcinoma, especially in biopsies
Dr. Calhoun #USCAP #BreastPath #pathology #PathX
My mnemonic for hairy cell leukemia phenotype. Remember the number 3! Maybe a bit of a stretch, but it works for me! #pathboards #knoworfail
It was almost 10 years ago when I diagnosed my first case of colchicine toxicity . Today, I saw my 2nd case.
Gastric biopsy in a patient with nausea and vomiting.
#Ringmitosis
#gout
Garrey Faller retweeted
#GUpath TURBT from today's signout showing what I call "3/4 rule" of MP invasion
(if tumor is three-quarters of the way around MP bundle but not technically IN bundle, I'll still call it MP invasion)
for good measure, lower power shots show more typically pattern MP invasion
Garrey Faller retweeted
#GUpath TURBT, prior high grade pTa PUC
yes there is some lovely PAX8 positive flat pattern nephrogenic adenoma, but you'll also notice background pTa PUC is ALSO PAX8 positive!
(NA was p63 neg; PUC was p63 pos)
⏬cont'd⏬
Garrey Faller retweeted
Lung - Lepidic pattern and micropapillary pattern can show as a ground glass lesion on imaging
That is why our job is to recognize the micropapillary pattern which is commonly missed (considered high grade, and any tumor with >20% of high grade component is considered poorly differentiated)
Even 5% of micropapillary or solid pattern is associated with worse outcomes
Classic micropapillary pattern (Pic 1)
Not so classic presentations of micropapillary pattern (pic 2)
Dr. Butt #JobPrepBootcamp #NIPCAP #pathology #PathX
What is your diagnostic criteria for cribriform Prostate cancer?
Experts can disagree with what is cribriform. Here is cancer without basal cells (pin4 not shown). Looks cribriform to me.
pmc.ncbi.nlm.nih.gov/article…
#pathology @slusagar #standardization
Prostate apex core needle biopsy.
Does this finding require a more careful apical dissection if a radical prostatectomy is performed ?
ie should we ever report? @slusagar
