@g_hellenthal

Professor at University College London. Statistical genetics, population genetics, email responding

Joined July 2021
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Currently advertising for a 3-year, Wellcome Trust-funded post-doc position at UCL: ucl.ac.uk/work-at-ucl/search… aiming to disentangle the interplay between environmental pressures and our epigenome -- please inquire and/or pass along!

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk
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Currently advertising for a popgen post-doc position at UCL: jobs.ac.uk/job/CSC206/resear… which includes opportunities to work on thousands of other unpublished genomes via collaborations -- please inquire and/or pass along!
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jobs.ac.uk changed the link for some reason -- it's this one now -- jobs.ac.uk/job/CSG467/resear… will let you know if they change it again!
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Great work from Maria Derakhshan identifying CpGs with high interindividual methylation variation in multiple tissues and ethnicities, with evidence their methylation marks are established in the early embryo -- congrats Maria (& Matt Silver)! academic.oup.com/nar/advance…

Tissue- and ethnicity-independent hypervariable DNA methylation states show evidence of establish...

Abstract. We analysed DNA methylation data from 30 datasets comprising 3474 individuals, 19 tissues and 8 ethnicities at CpGs covered by the Illumina450K a

academic.oup.com
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Great new work by @JavierMenRev on disentangling pre and post-admixture selection signals in Latin Americans using a new method; see our preprint -- thanks to all contributors!
Javier Mendoza-Revilla@JavierMenRev19 Nov 2021
Our latest work together with @g_hellenthal on detecting adaptive signals before and after European contact in admixed Latin Americans is out on @biorxivprepring 1/n biorxiv.org/content/10.1101/…

Disentangling signatures of selection before and after European colonization in Latin Americans

Throughout human evolutionary history, large-scale migrations have led to intermixing (i.e., admixture) between previously separated human groups. While classical and recent work have shown that...

biorxiv.org
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Great thread explaining our latest pre-print on disentangling pre and post-colonisation signatures of natural selection in Latin Americans, led by @JavierMenRev and @g_hellenthal. #CANDELA
Javier Mendoza-Revilla@JavierMenRev19 Nov 2021
Our latest work together with @g_hellenthal on detecting adaptive signals before and after European contact in admixed Latin Americans is out on @biorxivprepring 1/n biorxiv.org/content/10.1101/…

Disentangling signatures of selection before and after European colonization in Latin Americans

Throughout human evolutionary history, large-scale migrations have led to intermixing (i.e., admixture) between previously separated human groups. While classical and recent work have shown that...

biorxiv.org
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Garrett Hellenthal retweeted
Santos Alonso@salonsoLab29 Sep 2021
Today at 12, Lluís Quintana Murci @QuintanaMurci At 5pm Carlos Flores @LabCflores
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For those into fast haplotype-based admixture detection/dating, fastGLOBEROTTER out now (thanks Pongsakorn & Matthew!): ~4-20x faster than GLOBETROTTER. Possibly 2 fast & furious. Next up: GLOBETROTTER in outer space biorxiv.org/cgi/content/shor…
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Garrett Hellenthal retweeted
Leo Speidel@leo_speidel20 Jul 2021
Our paper “Inferring Population Histories for Ancient Genomes Using Genome-Wide Genealogies” is now published! This is our go at harnessing the amazing collection of ancient genomes available. Our approach reproduces many findings & makes new discoveries! doi.org/10.1093/molbev/msab1…

Inferring Population Histories for Ancient Genomes Using Genome-Wide Genealogies

Abstract. Ancient genomes anchor genealogies in directly observed historical genetic variation and contextualize ancestral lineages with archaeological ins

academic.oup.com
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