@fyarovinsky
Joined December 2015
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Bacteria promote kidney stones C. glucuronolyticum-like bacteria enriched in urine of calcium oxalate stone patients & promote CaOx crystallization via hippuric acid degradation & biofilm formation. Hippuric acid prevents bacteria-driven crystallization cell.com/cell-host-microbe/a…

Hippuric acid metabolism by Corynebacterium glucuronolyticum-like bacteria promotes calcium oxalate...

Qi et al. identify Corynebacterium glucuronolyticum-like (C. glucuronolyticum-like) bacteria enriched in the urine of calcium oxalate (CaOx) stone patients and show that they promote CaOx crystalli...

cell.com
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Prof. Nikolai Slavov
@slavov_nSep 29
Timescales in Cell Biology
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Jonathan Kagan@jkagan1Sep 23
Today, the Toll-like Receptors reveal a new mechanism of signal transduction: Receptor-Free Signal Transduction. nature.com/articles/s41586-0…

TRAM promotes Toll-like-receptor-free myddosome signal transduction

Nature - TRAM is a regulator of myddosome assembly through dissociating MyD88 from the TLR–TIRAP complex to enable myddosome maturation and durable downstream signal transduction.

nature.com
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Takei Lab@LabTakeiSep 14
cGAS–STING drives ageing-related inflammation and neurodegeneration nature.com/articles/s41586-0…

cGAS–STING drives ageing-related inflammation and neurodegeneration

Nature - The cGAS–STING signalling pathway is a critical driver of chronic inflammation and functional decline during ageing, and could be targeted to halt neurodegenerative processes during...

nature.com
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Dr. Thomas Ichim
@exosomeSep 14
Strongest Nature paper for us who love #cancer #immunology Tumors use nerves to tell the brain to suppress immune response to all the cancer to grow. nature.com/articles/s41586-0…

Tumour–brain crosstalk restrains cancer immunity via a sensory–sympathetic axis

Nature - Mouse models demonstrate that vagal sensory neurons transmit signals from lung adenocarcinoma to the brain, increasing sympathetic efferent activity in the tumour microenvironment and...

nature.com
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Cell@CellCellPressSep 11
Now online! Mitochondrial ATP promotes T cell differentiation through chromatin accessibility dlvr.it/TVRW6w

Mitochondrial ATP promotes T cell differentiation through chromatin accessibility

Cell-mediated immunity requires cytotoxic CD8+ T cells that adopt and maintain an effector phenotype. Here, D-α-hydroxybutyrate (DAHB) is shown to act as a metabolic adjuvant, driving the conversion...

cell.com
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Curious how AI can boost your publishing success? Join Dr. Ellen C. Fox for a look at the latest journal policies and smart strategies that let you harness AI’s power—while keeping trust and integrity at the core of your work. 📅 Sept 18 at 11:00 AM ET 🔗 Register today: ow.ly/UF3550ZLz0L. #PeerReviewWeek #AcademicTwitter
Webinar announcement on AI in scientific publishing with speaker Ellen C. Fox, PhD, scheduled for September 18, 2026, 11 a.m. to noon EDT.

ALT Webinar announcement on AI in scientific publishing with speaker Ellen C. Fox, PhD, scheduled for September 18, 2026, 11 a.m. to noon EDT.

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Cell@CellCellPressSep 2
Now online! Tabula Sapiens 2.0: A comprehensive transcriptomic atlas of human cell types dlvr.it/TVJ3yK

Tabula Sapiens 2.0: A comprehensive transcriptomic atlas of human cell types

An expanded atlas of human cells maps the expression of nearly all human transcription factors across 701 cell-type/tissue combinations and uncovers the heterogeneous nature of senescence across...

cell.com
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Jonathan Kagan@jkagan1Sep 2
Change the textbooks. Trans-splicing as a means to diversify the proteome. Many congrats to Ruaidhri Jackson and Olivia Venezia on this remarkable discovery. nature.com/articles/s41586-0…

Functional chimeric mRNAs encode proteins in mammalian immunity

Nature - Inflammation induces interchromosomal DNA interactions that bring parent genes into close proximity, facilitating the formation of chimeric mRNAs that encode physiologically relevant,...

nature.com
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Take the guesswork out of scientific writing. Dr. Bonnie N. Dittel breaks down the essential elements of a compelling manuscript designed to stand out in today’s competitive publishing landscape. 📅 Mon, Sept 14 at 11:00 AM ET 🔗 Secure your spot: ow.ly/Kzis50ZFVnb. #PeerReviewWeek
AAI webinar announcement for 'How to Write a Scientific Manuscript' with speaker Bonnie N. Dittel, PhD, on September 14, 2026, from 11 a.m. to 12 p.m. EDT.

ALT AAI webinar announcement for 'How to Write a Scientific Manuscript' with speaker Bonnie N. Dittel, PhD, on September 14, 2026, from 11 a.m. to 12 p.m. EDT.

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NIH
@NIHAug 26
🔬The NIH Stadtman Investigator Program is accepting applications for tenure-track positions in the NIH Intramural Research Program. As a faculty member in the IRP, you’ll join a dynamic research community offering stable funding, intellectual freedom, shared resources, and access to a wide range of scientific expertise. 📅 Apply by Sept. 30, 2026 🔗 Apply: irp.nih.gov/stadtman 📧 Questions? [email protected]
The image shows a large brick building with white columns, identified as part of an NIH Stadtman Investigator Program advertisement. The text reads, "NIH Stadtman Investigator Program: Tenure-Track Positions. Applications Due: September 30, 2026." Two NIH logos are visible at the bottom. The foreground features trees and bushes.

ALT The image shows a large brick building with white columns, identified as part of an NIH Stadtman Investigator Program advertisement. The text reads, "NIH Stadtman Investigator Program: Tenure-Track Positions. Applications Due: September 30, 2026." Two NIH logos are visible at the bottom. The foreground features trees and bushes.

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Developing life-saving polio vaccines took years of basic research and a public commitment to funding vaccine development. Discover how AAI members unlocked the mysteries of the virus and used those breakthroughs to bring polio close to eradication: ow.ly/tgmZ50ZBtwo.
Black and white photo of a child receiving a polio vaccine injection from a doctor in a clinical setting.

ALT Black and white photo of a child receiving a polio vaccine injection from a doctor in a clinical setting.

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Want to strengthen your manuscripts and streamline the submission process? Join Dr. Bonnie N. Dittel (EIC, @ImmunoHorizons) for practical advice on crafting a clear, rigorous scientific paper. 📅 Sept 14 at 11:00 AM ET 🔗 Register in advance: ow.ly/KYVs50ZAu4R. #PeerReviewWeek
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Ran Blekhman@blekhmanAug 9
Huge faculty recruitment effort at the University of Chicago -- a division-wide, open-rank search looking to hire about 20 faculty across 5 research areas in biology. Come be our colleague! Full announcement: uchicago.app.box.com/s/ckih9…
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Jonathan Kipnis 🟦
@jonykipnisAug 5
Very interesting work from Quintana lab || Antigen presentation by CD40+MHC-II+ astrocytes promotes CNS autoimmunity | Nature nature.com/articles/s41586-0…

Antigen presentation by CD40+MHC-II+ astrocytes promotes CNS autoimmunity

Nature - Astrocytes promote central nervous system (CNS) immunity through antigen presentation and activation of CD40 in astrocytes by CD40L expressed by CD4+ T cells in a model of experimental...

nature.com
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Andreas Baumler@abaumlerJun 19
Here a more detailed take on this story sciencedirect.com/science/ar…
Andreas Baumler@abaumlerJun 16
Is colorectal cancer driven by a disruption of anaerobiosis? A recent study by Spiga et al. makes this idea walk and talk like a duck. Read more here: sciencedirect.com/science/ar…
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A fascinating and unexpected discovery—who would have predicted that macrophages possess magnetic properties and can contribute to navigation through magnetoreception?science.org/doi/10.1126/scie…

Homing pigeon navigation relies on superparamagnetic macrophages under overcast conditions

Birds use a variety of navigational strategies, including the geomagnetic field, especially when other cues are not available, such as under overcast or nocturnal conditions. Magnetite particles in...

science.org
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Such a cool story! nature.com/articles/s41586-0…

Eosinophils drive intestinal remodelling and innate defence in reproduction

Nature - From pregnancy until lactation, eosinophils accumulate in the small intestine where they regulate goblet cell fate and enhance innate defences against enteric pathogens.

nature.com
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Miriam Merad, MD, PhD@MiriamMeradApr 30
Thrilled to see a new paper led by the outstanding @Brown_lab1, now out in Nature Biotechnology. We provide mechanistic insights into how mRNA vaccines work. challenging key assumptions and offering new ways to control vaccine activity. (1/3) Read here: nature.com/articles/s41587-0…

mRNA vaccine immunity is enhanced by hepatocyte detargeting and not dependent on dendritic cell...

Nature Biotechnology - mRNA vaccine efficacy is enhanced by silencing cell-type-specific expression.

nature.com
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This #DayofImmunology, we celebrate the "Guardians of Immune Balance"—Regulatory T Cells! 🛡️ Did you know a cornerstone of the 2025 Nobel Prize-winning research on Tregs was published in The Journal of Immunology? In 1995, Shimon Sakaguchi and colleagues identified CD25 as a marker for these essential suppressor cells, forever changing our understanding of immune tolerance. 📖 Read the classic in @J_Immunol: ow.ly/kMyt50YRPHX.
Cover of The Journal of Immunology featuring a study on T cells and IL-2 receptor alpha-chains in self-tolerance and autoimmune diseases.

ALT Cover of The Journal of Immunology featuring a study on T cells and IL-2 receptor alpha-chains in self-tolerance and autoimmune diseases.

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