@flxwae.bsky.social Previously Lattice Light-Sheet Microscopy @LabSauer. Now @ZEISS_Group developing optics for EUV lithography at 13.5nm. Views my own.
Joined October 2017
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Felix retweeted
We aim to speed up DNA-PAINT imaging by ~1.5 orders of magnitude. To do so, we introduce self-quenching Imagers end-labeled with two dyes (TDI-DNA-PAINT). In this work, ATTO Oxa14 (MR121) was found to be a suitable fluorophore. We will continue to explore further dyes in future.
🚨New preprint: “Two-dye imager (TDI)-DNA-PAINT allows up to 15-fold faster imaging at higher resolution and whole cell imaging in 4 hours.”
▶️Link: biorxiv.org/content/10.1101/…
Felix retweeted
🚨New preprint: “Two-dye imager (TDI)-DNA-PAINT allows up to 15-fold faster imaging at higher resolution and whole cell imaging in 4 hours.”
▶️Link: biorxiv.org/content/10.1101/…
It doesn't look to good for Twitter. Seems like entire teams for critical parts of infrastructure have left. This can't be good. theverge.com/2022/11/17/2346…
Isn't that what every parent has tried a thousand times? Graphical abstract makes it look like a baby is a machine and you only have to push the right button. Let me tell you: It's not. cell.com/current-biology/ful…
Felix retweeted
LOCAN: a python library for analyzing single-molecule localization microscopy data by Sören Doose ift.tt/UFidDKC
Felix retweeted
I am fascinated by the idea of funneling private money to finance basic research. There's so much excess of capital in certain parts of the world that we are going back to the XVII century approach of science done by the wealthy, without a tax-collecting state taking care of it.
I thought handling Lattice Lightsheet data was hard, but this is truly humbling. Imaged with the first (?) Zeiss MultiSEM and data to analyze for years to come 😊
Continuing Google Research's work on connectomics, today in collaboration with the Lichtman Lab at Harvard University, we have released a 1.4 petabyte rendering of a small sample of human brain tissue, & a companion paper. See the blog post for details!
ai.googleblog.com/2021/06/a-…
Felix retweeted
Looking for metabolic targeting/labelling strategies for sphingolipid de novo synthesis? Have a look at our recent paper @RoySocChem describing a clickable sphinganine precursor which is metabolized to ceramides even after click-reaction with organic dyes: xlink.rsc.org/?DOI=D0OB02592…
Exactly why I left academics after my PhD. Imo focusing on performance metrics will worsen research quality mid to long term.
Felix retweeted
1/24 A little while ago I tweeted about bad things happening at Liverpool University. What they are doing there is threatening to the entire academic community and the very idea of a university. Bare with me; I want to explain why (thread): xitter.cf/BentallProf/status/136…
In a move that looks completely illegal @LivUni is making staff redundant to replace them with 'better quality' academics; none failed to meet reasonable performance targets. Please, all academics everywhere, sign this open letter: docs.google.com/document/d/1…
#liverpoolredundancies
Felix retweeted
The dyes they are a-changin’ 🎶
Photoblueing can distort multicolor fluorescence imaging and FRET experiments. 🔬🚨❗️
nature.com/articles/s41592-0…
Felix retweeted
𝗦𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗰𝗼𝗹𝗼𝘂𝗿 𝗺𝗮𝗽𝘀
🆅7
fabiocrameri.ch/colourmaps
#useBatlow #endRainbow
#ScientificVisualisation #visualisation #colors
#OpenSource #Accessibility #proBonoWork
1/n
ALT The full suite of Scientific colour maps
Felix retweeted
1/6 We are delighted to present our work on pulsed interleaved MINFLUX. p-MINFLUX is a simplified implementation of the MINFLUX concept that provides 1-2 nm localization precision and access to lifetime information! Great collaboration with @TinnefeldLab!
pubs.acs.org/doi/10.1021/acs…
Glad to be a tiny part of it 😊
The world's most precise mirror from ZEISS enables extreme ultraviolet (#EUV) #lithography. At the German #DigitalGipfel20 CEO Karl Lamprecht presented EUV #technology to German Chancellor #AngelaMerkel. Watch the whole video🎬⬇
Image source: Bundesregierung / Guido Bergmann