โ Post-doctoral researcher in EpiMiC lab @INRAE_MICALIS โ Biochemist/Microbiologist โ Molecular microbiology, host-pathogen interactions, bacterial persistence
Paris, France
Joined May 2017
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๐ข Happy to announce that my postdoc work @inrae_micalis, showing the natural formation of osmotically stable wall-deficient bacterial cells upon dormancy in an aquatic environment, is now available as a preprint @biorxiv_micrbio (1/15):
biorxiv.org/content/10.1101/โฆ
One day... ๐ฅ๐ฅ๐ฅ๐
๐ฟ๐พ๐๐๐๐ถ๐ฐ๐ป ๐ฝ๐พ ๐๐พ๐ฟ-๐บ ๐ณ๐พ ๐ผ๐๐ฝ๐ณ๐พ!!! ๐
๐ต๐น Um desfecho histรณrico, uma campanha sem precedentes e um ๐๐๐
๐๐จ๐ซ๐ฅ๐ ๐๐ก๐๐ฆ๐ฉ๐ข๐จ๐ง๐ฌ๐ก๐ข๐ฉ ๐๐๐๐ para recordar para sempre! โจ
Que orgulho, Herรณis! โค๏ธ
#heroisdomar #andebolportugal #inspiredbyhandball
#HappyNewYear2025 !
A globally positive year for me (one great publication plus some rejected grants), as 2024 reaches its epilogue, I want to wish a successful 2025 to my scientific colleagues and collaborators. Eager to read your newest epic findings in the next 12 months!
ALT An AI-generated image of a cartoon stylized bacterium with a smiling face and arms, holding a flag with "2025" and a banner with "Happy 2025". Fireworks explode in the background.
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
๐ข Historic day for Portugal and phage therapy! ๐ต๐น A framework was approved, allowing magistral preparation of personalized phage products. ๐ Grateful to Jean-Paul Pirnay, my group @AzeredoLab Portuguese patients, and doctors who signed a petition inspired by the Belgium model.
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
The end of a long standing chapter - happy to see the latest contribution from my PhD @BIUPasteur out! @institutpasteur @BCI_Pasteur @lpiparis_
@univ_paris_cite
Many thanks to everyone who contributed - colleagues, friends, and family included!
1/6 Excited to share our new findings published today in @NatureMicrobiol, explaining what drives virulence heterogeneity in Listeria monocytogenes!
๐๐๐Congratulations to Lukas & all co-authors @LostInTranscrip @BIUPasteur
nature.com/articles/s41564-0โฆ
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
1/8 Publication Alert! Delighted to share the publication of a collaboration by Gerben Marsman (@zychlinsky lab @mpiib_berlin) and @xuhui_zheng (former PhD student in my lab) et al detailing how Histone H1 kills MRSA (cell.com/cell-reports/fullteโฆ).
This guy here also has a cozy corner in the ๐ต place. Hoping it can gain critical mass so we can all leave โ to the ๐คฎ.
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
New preprint! A new direction for my research program: Bacteria can use antagonism to forage for nutrients in microbial communities. Shoot spearguns with toxins into other cells and leak out nutrients!
biorxiv.org/content/10.1101/โฆ
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
Great new work from the groups of @Selim_Khaled_ , @MicroGap , and David Dubnau!
ComFB is a c-di-GMP and c-di-AMP binding protein family!
#subtiwiki
biorxiv.org/content/10.1101/โฆ
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
I had some help ๐ถ Teamwork makes the dream work! Checkout our latest preprint spearheaded by Jessica Burnier in a great collab with the labs of Waldemar Vollmer, @victornizet & Malcolm Winkler biorxiv.org/content/10.1101/โฆ
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
Characterization of a GpsB-associated regulator of PBP1a reveals the organization of the cell wall remodeling complex of ... biorxiv.org/cgi/content/shorโฆ #biorxiv_micrbio
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
A bacterial cell wall repair and modification system to resist host antibacterial factors biorxiv.org/cgi/content/shorโฆ #biorxiv_micrbio
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
You want to run antibiotic MICs according to best-practice clinical microbiology protocols, but you are not sure how? Our article will walk you through it all! Great to work with @nikikaderabkova @AyeshaMahmood2 and a pleasure to publish in @npjAMR. rdcu.be/dZp04 #AMR
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
How do mitochondria, the cellโs energy-producing organelles, perform competing metabolic processes?
Segregation into distinct populations โ one that makes energy-storing ATP molecules and one that does not โ could explain it
nature.com/articles/d41586-0โฆ
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
#weekendreading ๐๐ฌ
Microbiota-derived lysophosphatidylcholine alleviates Alzheimerโs disease pathology via suppressing ferroptosis
@Cell_Metabolism
cell.com/cell-metabolism/fulโฆ
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
Streptococcus pneumoniae epidemiology, pathogenesis and control
Henriques-Normark & co. explore recent insights into Streptococcus pneumoniae epidemiology, clinical disease and pathogenesis, as well as new treatment and prevention approaches
@BHN_Lab
rdcu.be/dZqzB
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
Bacterial cell wall, biofilm and morphology enthusiasts - our new preprint shows how E. coli manages to survive without its essential cell wall! Check it out ๐#microbiology #bacteria
@LeidenBiology
@ClaessenLAB
@HandeWinde
Enhanced extracellular matrix production provides protection to cell wall-deficient Escherichia coli biorxiv.org/cgi/content/shorโฆ #biorxiv_micrbio
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
TIL that E. coli K12 โ the most widely used strain of bacterium for biological research โ is named "K-12" because it was first isolated from a diphtheria patient staying in room K-12 of a Stanford University hospital in 1922.
Naming conventions in biology are weird!
๐ช๐บ Filipe Carvalho (NOW AT ๐ฆ @ffchcarvalho) retweeted
SUCROSE SELECTION IS WORKING!!!!
cscA flask has the sucrose invertase overexpressing. CscB flask has only the sucrose permease. Heavy innoculum on both sides so any slight cloudiness is due to initial innoc and trace LB from scooping. HUGE MILESTONE!!!
