Dietary and gut microbiota interventions matter for restoring the gut barrier Timmie A. Britton & Prof. @mgrover_gi update the role of the gut barrier in disorders of gut-brain interaction and interventions to improve it: 👉 Microbial dysbiosis from diet, disease, or antibiotics can leave the intestinal lining exposed to pathogens 👉 Using a simplified, less restrictive low-FODMAP diet might be prudent for improving gut barrier function mainly in IBS, but some evidence shows benefits in functional dyspepsia 👉 Complex dietary fiber blends support gut barrier function by serving as important energy substrates for select bacterial commensals that ferment them into short-chain fatty acids 👉 Glutamine and other amino acids shape enteric immunity, mucus production, and gut microbiota profiles 💡 Rather than expecting that one single nutrient or diet will improve gut barrier function, think of broad dietary patterns that are mostly plant-based and reduce saturated fatty acids 📚 Read more via @LancetGastroHep : thelancet.com/journals/langa…