Mathematical and Computational Population Genetics Microbial Evolution | Machine Learning in PopGen | CRISPR-Cas | Pan-genomes | HGT 🦠 ➔ 🧬 ➔ 💻 ➔ 🤔
University of Tübingen
Joined November 2018
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Join us as a #PostDoc @uni_tue for 2 years! Work on large-scale genealogical data, develop #machinelearning methods, make an impact by decoding local ancestries (ARGs), and improve #popgen and medical studies in collab. with @Boehringer. More info here: uni-tuebingen.de/en/universi…
If you are interested in microbial #pangenomes, join us @eseb2025 in Barcelona with Jesse Shapiro and Anna Dewar. Only two days left to submit an abstract!
eseb2025.com/call-for-abstra…
Franz Baumdicker retweeted
please spread the word about this theoretical population biology workshop in chicago in june! should be really fun nitmb.org/modeling-and-theor…
Franz Baumdicker retweeted
Is it “winner-takes all” when the simplest living things compete? Check out my fresh publication on phage coexistence in Science and a thread below🧵 science.org/doi/10.1126/scie…
Franz Baumdicker retweeted
The life of cells, recorded nature.com/articles/s41576-0…. We dive into the opportunities of DNA recording for understanding single cell dynamics. Fantastic collaboration with the @JShendure, @ElowitzLab, Gagnon, and Schier labs.
Franz Baumdicker retweeted
AstraZeneca's Centre for Genomics Research is hiring!
Check it out if you are interested in leading an exceptional team of scientists who apply innovative machine learning approaches to large scale genomic and multi-omic data for drug discovery.
lnkd.in/d54cpyvf
CRISPR arrays store "immune memories" of past invaders as spacers. But these memories aren’t permanent— frequent spacer deletions reshape the array.
We investigated the spacer deletion dynamics with our new reconstruction tool and learned a lot... 🧵
buff.ly/4fS4Iu3
Finally, across multiple CRISPR-Cas types and genera, we found no significant difference in deletion rates or lengths, suggesting that spacer deletions are likely not modulated by Cas proteins.
It is crucial to use reconstructed arrays to see these deletion patterns, as the position of spacers shifts toward the trailer end over time. I will post more details about our reconstruction tool SpacerPlacer later. But you can find the tool here: buff.ly/40QdDId
Franz Baumdicker retweeted
🎉 tskit 0.6.0 is released! 🎉
Thanks to our wonderful contributors, this is a bumper release. Read all about it at:
tskit.dev/news/20241106-tski…
Franz Baumdicker retweeted
This @PslQlife Winter School is gonna be A M A Z I N G ! Come to Paris and let's chat about Polygenic Adaptation, Quantitative Genetics, and Pop Gen!
“Polygenic Adaptation from Quantitative Genetics to Population Genomics”
👉🏼 Deadline: January 8, 2025
👉🏼 Detailed description and application
edu.bio.ens.psl.eu/spip.php?…
@NedaBarghi @FrancoisMallard @KatrinaMcGuiga3 @Lufpa @EvolOdonata @jsztepanacz @pdevillemereuil @henriqueteoton2
Franz Baumdicker retweeted
🧬🧬 𝙉𝙚𝙬 𝙋𝙧𝙚𝙥𝙧𝙞𝙣𝙩!!🧬🧬 Latest collab with the amazing Ming Li & Yue Feng labs!
How do phages bypass multi-layered defenses in bacteria? Spoiler: with equally complex anti-defenses!! 🧵👇 biorxiv.org/content/10.1101/…
