
CEO of SIRNAOMIC LTD (@02257hk) Serial biotech CEO & RNAi leader | Practical founder playbooks | Build business without sacrificing family & fun
Hong Kong
Joined April 2009
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Fai Poon retweeted
Sirnaomics (2257.HK): FDA endorses a 4-arm Phase 2b design.
Safety & immunogenicity standards confirmed
ALL Phase 3 preclinical safety complete
Pediatric waiver granted
3 assets, COX2 + TGF-beta: oncology, aesthetics, MSK.
#BiotechInvesting #RNA #sirnaomics
this is an old innitiative that i started. but will again soon
LEPURE BIOTECH’s BUS Initiative: Empowering Local Communities with Essential Biologics usawire.com/lepure-biotechs-…
30s video used up all my @doubaoAi credit. and now i have to use @WorkBuddy_AI
obviously, men initiate the act of pregnancy, and women allow it. Statistically speaking.
the style is call dulect. ask @ZoolanderMovie
Think twice before judging people based on their appearance
Readers added context they thought people might want to know
The video is AI-generated, not authentic footage. Steering wheel turns without matching wheel movement, a common AI physics artifact with no verified real-world source.
x.com/koehlersimon/s…
popsci.com/diy/how-to-spo…
mashable.com/article/how-to…
this is kind of big. now we have a good shuttle for BBB
Congrats to Denali for their FDA Approval of AVLAYAH!
Fun bit of biotech history. The bi-specific shuttle technology used in Avlayah came from F-star, a European biotech we helped seed in 2006 (thx Regina Hodits). They were advancing a bi-specific mAb format for a range of uses. Image below is from their 2006 pitch to us.
F-star did a collaboration with Denali to use their "Fcab" technology for BBB shuttles in 2016, when the now 10-year old biotech was figuring out what programs to advance internally vs in collaboration nature.com/articles/d43747-0…
In 2018, seeing momentum in their BBB programs, Denali acquired the subsidiary housing the BBB technology, called F-star Gamma. fiercebiotech.com/biotech/de…
With the approval of Avlayah, F-star's original technology thesis finally made it to market for one of the many postulated uses... 20 years later... Atlas Fund VII, a 2005 vintage fund, will be getting a small but fun milestone payment for approval...
Biotech is a long game, played by teams across the ecosystem collaborating in different ways over decades. Huge kudos to Ryan Watts, @rtnarch, and the team at Denali for their persistence in pushing Avlayah forward to patients.
hahaha.. this make my grad school so lame
A PhD student kisses the scary professor on purpose so her friend can have the other guy. Then they have to keep kissing on purpose.
The Love Hypothesis (2026)
BookTok fake-dating in a lab coat. Lili Reinhart plays Olive like she’s about to drop a beaker. Tom Bateman plays Adam like the hallway already belongs to him. The hypothesis is not subtle.
thank u for medical.advancement
In 1991, Patricia Stallings was sentenced to life in prison for allegedly poisoning her infant son with antifreeze.
But while she was behind bars, she gave birth to another baby. He was immediately placed in foster care—and weeks later, he became seriously ill with symptoms almost identical to those that had killed his older brother.
There was just one problem: Patricia had never been in contact with him.
Doctors eventually discovered the real cause: methylmalonic acidemia, a rare inherited metabolic disorder that can produce chemical findings resembling ethylene glycol, the main ingredient in antifreeze.
Scientists reexamined her first son’s blood and found that the original laboratory results had been misinterpreted. The evidence that had helped convict Patricia was wrong.
She was released in 1991, and prosecutors dropped the case after concluding that her son had not been poisoned.
A mother lost her child, her freedom, and nearly two years of her life—because a rare disease looked like murder.






















