University of Michigan • Led by Dr. Nico Bohnen • To better understand cognitive function & mobility changes in neurodegenerative disorders & normal aging
Ann Arbor, MI
Joined February 2022
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Check out Jeff's newest critical review of ketogenic interventions in neurodegeneration with significant implications for current & future clinical neurology practice: frontiersin.org/articles/10.…
Fay Pongmala from our lab as a new paper out:
pubmed.ncbi.nlm.nih.gov/3656…
Clinical assessment of self-efficacy is highly relevant to understand and treat PIGD motor features in Parkinson disease.
Check out our new paper in Brain Communications showing for the first time evidence of discordance between anterior vs posterior brain cholinergic vs blood flow dependence. Special kudos to Steve!
academic.oup.com/braincomms/…
Our colleague Dr. Fay Pongmala has a new paper out how trunk flexion in people with Parkinson may negatively affect gait, in particular gait speed and step length. Check it out: sciencedirect.com/science/ar…
Our former PHD student Sygrid van der Zee has a new paper out from our lab showing that cholinergic integrity of a centrocingulate neural network is a robust predictor of cognitive impairment in people with PD. Check it out: frontiersin.org/articles/10.…
Prabesh Kanel has a new paper out on cholinergic losses in PSP compared to Parkinson. Check it out:
pubmed.ncbi.nlm.nih.gov/3622… Differential PD vs PSP cholinergic vulnerability well extends beyond the tectum
Our new perspective paper on noninvasive cholinergic targets in Parkinson is out: pubmed.ncbi.nlm.nih.gov/3620… There may also be cholinergic targets in the gut-brain axis.
Check out our new paper at movementdisorders.onlinelibr…
This study provides new evidence that increased vestibular burden during multisensory postural control processing may be specific for freezing of gait rather than falls in Parkinson.
Our new study shows that efficacy of vestibular processing during sensory conflict while standing is a determinant of abnormal balance in Parkinson's disease with lesser contributions of visual and somatosensory functions: sciencedirect.com/science/ar…
Our new paper is out in JNT pubmed.ncbi.nlm.nih.gov/3575…
Cholinergic neural network correlates of #vestibular sensory conflict testing in people with #Parkinson including small brain nuclei, in particular the medial geniculate, that are important for freezing, falls and imbalance.
Join University of Michigan Udall Center's Virtual Community Research Symposium on Friday June 24th from 1-4PM EST to hear more about Parkinson disease and relevant research being conducted! Use link michmed.org/Bzdjz to register. See you there!
Functional Neuroimaging, Cognitive & Mobility Lab retweeted
Our Functional Neuroimaging, Cognitive and Mobility Lab @fNiCoMoLab would like to congratulate Dan McEachin who was recognized as a 2021 Citizen Scientist Champion Honoree.
globalalzplatform.org/awards…
@GAP_Foundation
youtube.com/watch?v=QklTZAgX…
Check out UM Department of Radiology's long time research volunteer Dan McEachin, who is the 2021 Scientist Champion Elevated Honoree from the Global Alzheimer's Platform Foundation. Congratulations Dan and thank you for your advocacy!
youtube.com/watch?v=QklTZAgX…
Functional Neuroimaging, Cognitive & Mobility Lab retweeted
Recent work using 18F-FEOBV PET with our colleagues in @umichmedicine #neurology reveals a specific topographic pattern of regional vulnerability of cholinergic nerve terminals across multiple cholinergic systems in normal aging. Out now in #AgingBrain: sciencedirect.com/science/ar…
Dr. Kanel’s recent work in #AgingBrain showing a specific topographic pattern of regional vulnerability of cholinergic nerve terminals across multiple cholinergic systems that accompany aging:
sciencedirect.com/science/ar…
Functional Neuroimaging, Cognitive & Mobility Lab retweeted
Our latest work with colleagues in @umichmedicine #Neurology investigating the dopamine agonist modulation of [18F]FEOBV #PETImaging in #ParkinsonsDisease is out now in @Mol_Pharm. Read it here: pubs.acs.org/doi/10.1021/acs…
Dr. Bohnen’s latest review paper examining cholinergic changes in Parkinson’s disease
In their Review, Professor Nicolaas Bohnen and colleagues provide an update on cholinergic systems and changes in Parkinson's disease and isolated REM sleep behaviour disorder, a Parkinson's disease prodrome.
thelancet.com/journals/laneu…
