Cambridge, MA
Joined October 2017
Eshaan Iyer retweeted
Check out the @BagotLab latest publication in @NatureNeuro featuring @esiyer and me! Here, we identify sex specific roles for nucleus accumbens afferents from the ventral hippocampus and medial prefrontal cortex in encoding aversive information. 1/12 nature.com/articles/s41593-0…
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There’s a lot known about mPFC-NAc and reward. Given that inputs from the vHip converge with mPFC inputs in NAc, we wanted to understand how these two circuits might be working together to support reward processing
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This work hi-lites the often overlooked role of redundancy in neural circuit control of behavior. Redundant encoding allows for simple integration of multiple circuits. Specificity in how each circuit is engaged supports granular encoding (amplifying impact of unexpected reward)
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Ultimately we need to move beyond thinking about individual neural circuits in isolation and towards understanding how neural circuits function in relation to each other
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Excited to share a new preprint from the lab! Here we unpack the apparent redundancy in how mPFC and vHip inputs to the NAc shell integrate reward. We identify a novel motif of reward integration that is common to both inputs but used differently biorxiv.org/content/10.1101/…
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