@eric_fischeri
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Eric Fischer retweeted
If you attend one scientific meeting next year, do not miss the joint Keystone Targeted Protein Degradation and Proximity Therapeutics, January 21-24, 2024. Promises to be a fireworks display of disease biology, chemical solutions and rising investigational agents. Bring your ideas, laptop and snowboard, to the Keystone Resort. Abstract deadline is October 26. See you there!
Targeted Protein Degradation
keysym.us/KSProteinDeg24
Proximity Based Therapeutics
keysym.us/KSProximityTx24
Eric Fischer retweeted
We present the structure of BIRC6, an essential Inhibitor of Apoptosis protein (IAP) and hybrid E2/E3 enzyme. IAPs bind & inhibit caspases, and this inhibitory action is relieved by binding of Smac.
biorxiv.org/cgi/content/shor…
Eric Fischer retweeted
So grateful to receive generous support from @DamonRunyon both during my postdoc and when I start my independent group❤️ Can’t wait to continue my research in engineering new proteins to study cancer biology @HMS_BCMP @DFCI_ChemBio. Lab officially opens in less than one month!!!
We're excited to announce six new recipients of the Damon Runyon-Dale F. Frey Award for Breakthrough Scientists, recognizing Fellows whose work has the potential to transform the way we prevent, diagnose and treat cancer. Learn more about their work here: bit.ly/34h71r3
Eric Fischer retweeted
If you missed my talk earlier, we are doing a community call for degraders (glues/bifunctionals) to expand mapping of the degradable proteome.
You send us degrader, we return global proteomics data (for free).
If interested, please follow the link to the submission form attached
Eric Fischer retweeted
We solved the structure of HUWE1. Looks familiar..
Preprint here: biorxiv.org/content/10.1101/…
Eric Fischer retweeted
Thank you to @fischerlab1 and @df_hcc for hosting me today in their #ConnectScience series. It is inspiring to see how scientific communication continues despite this awful pandemic.
Eric Fischer retweeted
Excited about this event - our speakers include @mbogyo, @katecarroll_lab, @CherylArrowsmi1, @alessiociulli, @DevlinLab, @AnnaGreka, @giuliosf, @kaelin_lab, @jennifercpetter, @hargrovelab, @drcmwoo! We built time for panel discussion and posters! Join us!!!#TranslationalChemBio20
We are co-organizing a virtual conference on #TranslationalChemBio20 with @DFCI_ChemBio and @NatRevDrugDisc. Please join us on October 5-6 to learn how recent advancements in chemical biology have impacted cancer research and therapies. You can register at go.nature.com/33HNRZb
Eric Fischer retweeted
As an immunologist, I’m fortunate to have known Tony Fauci for 40 years and have the highest regard for his skill, knowledge, judgment, commitment and character. We need his leadership, and his clear-eyed assessments and advice about the COVID-19 pandemic. Lives depend on it.
Eric Fischer retweeted
The kinase inhibitor CR8 is a molecular glue degrader that selectively depletes cyclin K. CDK12 acts as a glue-induced substrate receptor. We are very excited to share our new story in collaboration with the Ebert lab @biomiko @zkozicka @gpetzold2 go.nature.com/2AALQS5 @nature
Eric Fischer retweeted
(Free) registration is now open for the 5th New England cryo-EM symposium at @harvardmed on April 27! cellbio.med.harvard.edu/5th-…
Eric Fischer retweeted
if you've been wanting to run Rosetta via a Jupyter notebook, install using Conda, or run your design/prediction jobs using cloud compute, check out our newest tools article in Protein Science:
doi.org/10.1002/pro.3721
Eric Fischer retweeted
Did you have your morning DCAF15 already? With E7820/indisulam/tasisulam #tpd #proteindegradation T. Faust @HojongYoon @kdonovan1008 @fischerlab1
Eric Fischer retweeted
DFCI Center for Protein Degradation is looking for PhD level scientists with backgrounds in:
-Immune oncology
-Animal models
-Cellular and Biochemical assays
-Rosetta Modeling
For more information: cpd.dana-farber.org/join-us.…
Eric Fischer retweeted
@TheMarkFdn announces the #EmergingLeaderAwards, 8 grants to promising early career scientists for projects aimed at addressing substantially unmet needs in cancer risk prediction, prevention, detection, & treatment bit.ly/2QodiEK #ConceptsToCures
Eric Fischer retweeted
Dana-Farber (@DFCI_ChemBio, @fischerlab1) and Deerfield Management to create a Center for Protein Degradation, which will interrogate and advance a large portfolio of advanced protein degrader targets while creating a next-gen protein degrader platform: ms.spr.ly/6017rC0PX
Eric Fischer retweeted
Wondering how we deliver the search results at useKit.com/ ? Read the blog about our search implementation - bit.ly/nRO7Tm
Eric Fischer retweeted
E-Mail sent out to our testing users to try out the new useKit features and giving feedback. Thanks to all our testers. ^NR
20 Minuten Online - «Google Wave wollte zu viel auf einmal» - Webpage 20min.ch/digital/webpage/sto…