Translational oncology scientist passionate about improving cancer patients’ lives through improving access to clinical trials.
Nashville, TN
Joined August 2010
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Excited to share our preprint where we identified impaired mitochondrial metabolism as a driver of epithelial plasticity and primary tumor escape in metastasis. This was a big collaboration with lots of people from VUMC as well as the NCI!
Happy to share @enarner preprint on mitochondrial metabolism and kidney cancer metastasis--This ongoing project started with @KimrynRathmell using patient data to show inhibition of oxphos promotes EMT and primary tumor escape. Great work Emily!
biorxiv.org/content/10.1101/…
So excited to be at #AACR25 in Chicago and receive a scholar in training award from the Kidney Cancer Association (@kidneycan) and the Chris CJ Johnson foundation (@renalmedullary). I’m learning so much. If you see me around, please say hi! #SITAKIDNEY #DayintheLife @kaydaustin
Finished off the night at the scholar in training reception, where I networked with so many other amazing early-career investigators as well as @kidneycan @KidneyCancer and @kaydaustin!
Emily Baker, Ph.D. retweeted
We are excited to honor the incredible physician-scientist @KimrynRathmell with @AmericanCancer most important award. Her passion to combine science and care to improve patient outcomes with #kidneycancer is an inspiration to us all pressroom.cancer.org/2025Med…
Emily Baker, Ph.D. retweeted
#UTSW scientists have discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers along with a new druggable therapeutic target to block it. @brekkenlab @scisignal bit.ly/4ggudoJ
Emily Baker, Ph.D. retweeted
Studying the mechanisms of #EpithelialToMesenchymal transition, researchers investigated the kinase AKT and identified a pathway centered on TBK1 required for EMT and metastatic spread in pancreatic cancer in mice. @UTSWCancerBio @brekkenlab @enarner scim.ag/41KOxea
Emily Baker, Ph.D. retweeted
AXL-TBK1 driven AKT3 activation promotes metastasis | Science Signaling science.org/doi/10.1126/scis…
Long saga, but it is out. @enarner and a host of others pushed this through. Special thanks to Jim Lorens and his lab @UiB
It’s finally out!! It’s been 3 years since I graduated with my PhD from UTSW, but my last first-author paper from grad school and the culmination of my thesis work has finally been published in @scisignal!! science.org/doi/10.1126/scis…
We found that TBK1 activates the specific AKT isoform, AKT3, to drive stability of EMT transcription factors for subsequent EMT and metastasis!
Thanks to Rolf and everyone in the @brekkenlab for not giving up and pushing this out the door! Especially Dina and Jill! I’m extremely grateful to the whole crew and glad to see this out there!
Emily Baker, Ph.D. retweeted
Great to see this story out @jclinicalinvest by @Newcomblab
Sex differences and immunometabolism
jci.org/articles/view/177242…
Emily Baker, Ph.D. retweeted
For a PhD student, choosing a good lab is 10 times more important than choosing a particular topic to study
You’ve been staring at ATAC-seq results too long when the mountains start to remind you of chromatin accessibility peaks 🤦🏻♀️ #postdoc #atac #sciencetwitter
What Kelsey said! Congrats to the amazing @DarrenHeintzman! This project was a huge undertaking and it’s a privilege to be a part of it. Check out the latest paper from the @JeffRathmell lab to see how temperature influences immune cells!
Check out the latest drop from the @JeffRathmell lab by the extraordinary @DarrenHeintzman! This project was intellectually stimulating for all in the lab and fun to be a part of. See how temperature impacts T cell metabolism! science.org/doi/10.1126/scii…
🌡️🔥
Emily Baker, Ph.D. retweeted
Another Rathmell lab retreat in the books. Great to have @denis_mogilenko, Haake, Beckermann, @frank_m_mason and more join
Emily Baker, Ph.D. retweeted
Happy National Postdoc Appreciation Week! I want to personally thank our @theNCI postdocs and trainees for their dedication and innovation. Your work is pushing the boundaries of #CancerResearch and helping to shape a brighter future. I’m proud to work alongside you! #NPAW2024