Neuroscience lab in the Department of Cell Biology at Emory Univeristy studying everything from locomotor circuitry to neuroinflammation following PNI

Emory University
Joined April 2022
Huge congratulations for another successful semester of research and poster presentations by our lab's undergraduates. Desi Ukmar and Veronica Sanchez (Sr), Rodrigo Garcia (Jr), Briella Lucadamo (Soph), and their mentors @ZoeHaleyJ @PottorfTana Elizabeth Lane. @emorycollege
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We are thrilled to (re)introduce our recent graduate, Dr. Olivia Mistretta! 🥳 Although she will be missed, she is destined for a great career as a scientific writer and aspiring MSL. Congratulations Dr. Mistretta!! @neurophd_emory @EmoryMedicine @EmoryUniversity
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New paper drop from our graduate student Andrew Worthy on spinal cord V1 interneurons shaping motor output. @laneygradschool @neurophd_emory @EmoryMedicine
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Former Postdocs Ryan & Paula and current @neurophd_emory student @willieneuro share their work on how GABA/glycine neurotransmission on regenerating motoneurons facilitates axon growth and muscle reinnervation. @laneygradschool @EmoryUniversity
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This past week, senior graduate student @PottorfTana was awarded the prestigious @NIH Outstanding Scholar in Neuroscience Award! 🥳🥳🥳 #OSNAP #OSNAP2024 @NINDSfunding @NIH_NINDS @ncats_nih_gov @EmoryUniversity @EmoryMedicine @laneygradschool
Beautiful weather to visit Bethesda, talk science, and be a recipient of the 2024 Outstanding Scholar in Neuroscience Award Program #OSNAP #osnap2024 @NIH_NINDS @NIH @ncats_nih_gov
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Are you an Emory User with a gorgeous microscopy image? Please consider entering the ICI-Core Day Image Competition. Grand prize is $200. Images are due by 11/8 cores.emory.edu/ici/news/202…
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Our highly collaborative Department of Cell Biology is recruiting for a tenure-track faculty position! Come leave an impact on this world with us!
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Senior graduate student @PottorfTana representing the neuroimmune side of the Alvarez lab at @PNSociety1 in Montreal!
Very proud to have brought a sprinkle of the spinal cord to @PNSociety1 #PNS2024
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We may be at the PNS meeting but there are lots of implications from PNI in the CNS! Interested? Come check out my work for a flash talk today at 10:45am or a poster Monday at 2:15 (poster # P350) #PNS2024
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Big congratulations to our senior graduate student @PottorfTana recently being awarded the 2024 @NIH #OSNAP. We look forward to sending her to Bethesda in November to share our neuroimmune work and meet with NIH program officials🥳 @EmoryMedicine @neurophd_emory @laneygradschool
Absolutely thrilled to share I have been selected as an award recipient for the @NIH #OSNAP 2024 cohort. Looking forward to meeting all my fellow recipients and sharing some of my data on microglia-motoneuron dynamics in November! 🎉 Big thanks to the A lab for continued support.
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Inhibitory interneurons, such as Foxp2-V1, are crucial for motor development and are affected at early stages of pathology in motor neurodegenerative diseases like ALS. Here, graduate student @aeworthy presents a comprehensive examination of V1 subtypes. elifesciences.org/reviewed-p…
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@aeworthy is a 1st-year neuroscience PhD pre-candidate who recently joined our lab to perform his dissertation through @neurophd_emory @laneygradschool @EmoryMedicine @EmoryUniversity Before grad school, Andrew received his BS from @emorycollege and was a research specialist.
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One of our senior undergrads, Celia Bianco, defended and received Highest Honors for her thesis on the age-dependent involvement of C1Q after peripheral nerve injury in mice. We wish Celia the best with her future endeavors @emorycollege @Emory_NBB #opentowork
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The Alvarez lab is very proud of our graduate student @willieneuro for his presentation on tools for high res EMG's at the Sensorimotor Circuits for Limb Control meeting @OISTedu this past March, and additional presentation @EmoryUniversity @emoryDSAC GDBBS Research Symposium.
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We are very proud to share one of our senior graduate students' work in developing a novel way to study locomotor development in mice. It is Olivia's hope that "this technique will bring new insights to neurodevelopmental disorders, movement disorders, and so much more."
➡Olivia C. Mistretta et al. present novel methods to study neonatal air-stepping in newborn mice in this newly published research. 🖱 ow.ly/nbpx50QLIjF @LabLerit #AirStepping #neonates #kinematics #RhythmicLocomotion
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We are excited to share the following publication which was a joint effort with the Cope lab @GeorgiaTech Herein, we elucidate the differing effects on spinal cord plasticity and inflammation between crush and cut peripheral nerve injuries. 🧵 cell.com/cell-reports/pdfExt…
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Figures 4-5: We see increased peripheral immune cell infiltration into the spinal cord in the cut compared to the crush. This corresponds to differing microglia CCL2 (a pro-inflammatory chemokine) expression. 6/n 🧵
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Figure 6-7: If ccl2 is ablated from microglia, the sensory afferent -> motoneuron synapses (quantified via VGlut1) are preserved, muscles are still reinnervated, however, the stretch reflex remains lost. Further, ccl2 ablation does not alter amount of peripheral infiltration.
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