Edward Schenck MD (@edschenck) header
Edward Schenck MD (@edschenck) profile picture

Edward Schenck MD

@edschenck

Clinical translational researcher interested in necroinflammatory cell death in sepsis, acute lung injury, research methods and epistemology in medicine

 Manhattan, NY
vivo.weill.cornell.edu/display/cwid-ejs9005
Joined April 2012
  • Tweets5.1K
  • Following709
  • Followers990
Edward Schenck MD retweeted
Intensive Care Medicine (@yourICM) profile picture
Intensive Care Medicine@yourICM16 Jun 2023
#ARDS @ESICM guidelines 🫁 definition 🫁 phenotyping 🫁 #HFNO 🫁 CPAP/NIV 🫁 low tidal volume MV 🫁 PEEP & recruitment maneuvers 🫁 prone positioning 🫁 neuromuscular blocking agents 🫁 extracorporeal life support #ECMO #ECLS #ECCO2r #FOAMcc on @yourICM 🖇️ bit.ly/43J1OCe
Image from Intensive Care Medicine (@yourICM)
12
350
27
763
294,296
Edward Schenck MD retweeted
Adam Rodman (@AdamRodmanMD) profile picture
Adam Rodman@AdamRodmanMD16 Jun 2023
Can GPT-4 solve really hard medical cases and come up with a good list of differential diagnoses? @zahirkanjee @byrondcrowe and my study is out in @JAMA_current , and the short answer is, “Yes.” But what does this all mean? 🧵⬇️ xitter.cf/JAMA_current/status/16…
JAMA (@JAMA_current) profile pictureJAMA
@JAMA_current15 Jun 2023
In this study, a generative artificial intelligence (AI) model provided the correct diagnosis in its differential in 64% of challenging cases and as its top diagnosis in 39%. ja.ma/3X5M6i9
17
69
15
222
196,994
Edward Schenck MD retweeted
Frank Harrell (@f2harrell) profile picture
Frank Harrell
@f2harrell14 Jun 2023
Replying to @arthur_alb1
Typically you'd consider death as worse than other outcomes.
3
2
16
3,840
Edward Schenck MD retweeted
Paul Young (@DogICUma) profile picture
Paul Young@DogICUma14 Jun 2023
The @PATCHTrial, led by @RussellGruen, a study of pre-hospital TXA for severe trauma in adults at high risk of acute traumatic coagulopathy treated in advanced trauma systems, has been published today in @NEJM. #CCR23 Here’s a summary of what we did... nejm.org/doi/full/10.1056/NE…

Prehospital Tranexamic Acid for Severe Trauma | NEJM

Whether prehospital administration of tranexamic acid increases the likelihood of survival with a favorable functional outcome among patients with major trauma and suspected trauma-induced coagulop...

nejm.org
6
144
16
328
137,060
Edward Schenck MD retweeted
Paul Young (@DogICUma) profile picture
Paul Young@DogICUma14 Jun 2023
So, based on all of that, you tell me, should we implement (or continue to use) pre-hospital TXA in advanced trauma systems for adults at risk of acute traumatic coagulopathy?
66%Yes
17%No
17%Don't know
779 votes • Final results
3
3
2
9
17,572
This is the critical point.
Paul Young (@DogICUma) profile picturePaul Young@DogICUma14 Jun 2023
Replying to @DogICUma
Third, although no-one wants to survive with a bad outcome, but it is important to remember that many people who survive in a dependent state are glad to be alive.
1
338
Have to read in detail. One of the more important things for us to consider is adequacy of the adequate functional outcome endpoints…
Critical Care Reviews (@CritCareReviews) profile pictureCritical Care Reviews@CritCareReviews14 Jun 2023
Replying to @PATCHTrial
@PATCHTrial #PATCHtrial #CCR23 @karimbrohi Delighted to play an active role in contributing to the dissemination of high quality clinical research thanks to @NEJM for collaboration for simultaneous publication
Image from Critical Care Reviews (@CritCareReviews)
1
596
There is likely some truth to this statement, but keep in mind the term "small differences". This is not a call for nihilism regarding resuscitation.
Josh Farkas MD 💊 (@PulmCrit) profile pictureJosh Farkas MD 💊
@PulmCrit9 Jun 2023
hemodynamic tinkering in septic shock won’t affect mortality. IMHO if you get source control & antibiotics right, small differences in hemodynamics won’t super matter.
1
1
2
478
Let me do one for critical care. Adjusting for severity of illness, the in-hospital course has no effect on the post icu recovery (restricted to survivors).
Richard McElreath 🐈‍⬛ (@rlmcelreath) profile pictureRichard McElreath 🐈‍⬛@rlmcelreath2 Jun 2023
Love the crisis of interpretation these slides have caused. Great example to expose how confusing statistical "adjustment" can be. Adjusting for being tired, people who sleep more hours are no more aware than those who sleep less.
4
649
Recommend reading for people interested in the history of medicine as it intersects with technology disease and society. It’s really good.
Tina Chen (@tchen383) profile pictureTina Chen@tchen38325 May 2023
Book reading of “The Autumn Ghost” by @wunschcritcare at the @TheCornerBooks1. #Origin story of modern #CriticalCare.
Image from Tina Chen (@tchen383)
5
717
Isn't there a town somewhere that has something to do with this?? Lake Wobegon... yeah that's it.
Bojan Tunguz (@tunguz) profile pictureBojan Tunguz
@tunguz18 May 2023
Concerning
Image from Bojan Tunguz (@tunguz)
1
6
2,264
Who's reading The Autumn Ghost? Dr.Hannah Wunsch's suspenseful account of the polio epidemic and its impact on the evolution of critical care will keep you glued to the pages. Available at Amazon, Barnes & Noble, and independent bookstores @SOCCA_CritCare @ASALifeline @SCCM
Image from SCCM Anesthesiology Section (@SCCM_Anesth)
2
17
34
3,372
I have a really hard time thinking about how to balance societal implications RE: ai (meaning llm) are intellectual property theft at scale and the potential benefit of democratizing expertise
315
One of the more interesting things about generative ai in medicine is that it’s fluency will likely abrogate the need for structured icd10 style documentation… one can dream
2
2
722
Edward Schenck MD retweeted
Hannah Wunsch (@wunschcritcare) profile picture
Hannah Wunsch@wunschcritcare9 May 2023
Publication day for The Autumn Ghost! Thanks to @greystone @Inkwellmgmt and so many fellow writers for all the support An important story from medical history #polio #ICU #mechvent #ironlung #vaccineswork #disabilityinclusion Links to order hannahwunsch.com/index.html
Image from Hannah Wunsch (@wunschcritcare)
11
27
8
89
36,728
Important point for all things digital medicine. Are we measuring important things for humans? Even if we can, should we?
Richard McElreath 🐈‍⬛ (@rlmcelreath) profile pictureRichard McElreath 🐈‍⬛@rlmcelreath4 May 2023
In stats consultations lately, common problem across domains has been that scientists want to start with what they have measured (or can download) instead of what they would ideally want to measure. Gotta back them up and get them to science before stats. Hard.
68
This is an excellent point. These (Clinical AI) should be held to similar standards as medications. Let's hear it for blinding and randomization!
David Ouyang, MD (@David_Ouyang) profile pictureDavid Ouyang, MD
@David_Ouyang3 May 2023
Tremendous anchoring effect with AI, even the best radiologists were wrong >50% when AI gave the wrong suggestion. Very much suggests blinding and randomization necessary to truly evaluate these systems.
5
12
3,377
"the potential harms feel so profound, and all the positive applications basically have to do with increased efficiency. Efficiency isn’t higher on the list of things to pursue than human flourishing. So what is the “why” for you? nytimes.com/interactive/2023…
1
323
This issue is smile and curiosity on a page.
Science Magazine (@ScienceMagazine) profile pictureScience Magazine
@ScienceMagazine27 Apr 2023
The @ZoonomiaProject’s sequencing of more than 240 mammal genomes is paving new roads for understanding mammalian diversity and evolution and ourselves. Learn more in a new special issue of Science: scim.ag/2oO #Zoonomia
Image from Science Magazine (@ScienceMagazine)
372
Load more