Pinned Tweet
I’m excited to share our latest study led by
@GiuliaPasquesi out today in @CellPressNews , uncovering a new way transposons have been repurposed for human interferon signaling! Read on for a thread on cryptic splice variants, decoy receptors, and viruses (1/N) 👇🧵
Edward Chuong retweeted
Start the new year with a new publication! Led by the talented postdoc @YoseopYoon !
RBBP6 anchors pre-mRNA 3′ end processing to nuclear speckles for efficient gene expression: Molecular Cell cell.com/molecular-cell/full…
Edward Chuong retweeted
Our new paper defining the role of H3K36 methylation in regulating cell fate and plasticity is available online: rdcu.be/d5AEc
Thanks to @ar_swearingen and our entire team for their tireless work and to the editors at @NatureCellBio for the opportunity!
Edward Chuong retweeted
Check out our latest pre-print: we show that the LINE-1 retrotransposon is a potent source of chromosomal rearrangements and instability in addition to insertional mutagenesis using shotgun and long-read WGS.
@KathleenHBurns @JenniferAKarlow
biorxiv.org/content/10.1101/…
All credit for this discovery goes to amazing postdoc
@GiuliaPasquesi , who noticed the isoform in her 2020 Lockdown SideProject (tm) and drove this project start to finish. It was an honor to be a part of it. Look out for her--she's on the job market! 😉
See also a highly complementary deep dive into exonization in the same issue of Cell by @YagoArribas cell.com/cell/fulltext/S0092…
Delighted to share our study out today in @ScienceAdvances, led by Atma Ivancevic @jumpin_genes on endogenous retroviruses functioning as MAPK-regulated enhancers in colorectal cancer!
Big thanks to collaborators @LilyNNguyen @earth2olive @bitlerlabucd and @NIGMS and @AmericanCancer for supporting this work!