Cardiologist @UCLAHealth, Asst Prof @dgsomucla. Husband of PICU doc & dad of 2. Scientist, NIH-funded: HIV, COVID, TB affect 🫀. global/local/equity
Los Angeles, CA
Joined July 2016
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Matt Durstenfeld, MD MAS retweeted
In the COMBO-HF-X pilot trial @ZSFGCare, we found that a customizable heart failure polypill was feasible & improved adherence to quadruple therapy
@JACCJournals
@UCSF
@StanfordCVI
@durstenfeld @HsuePriscilla @JonathanDavisHF
@kardiologykazi
@EliseRiley_
@ATSandhu
@paheidenreich
Matt Durstenfeld, MD MAS retweeted
Authors show the PREVENT algorithm from the American Heart Association does not adequately predict #cardiovasculardisease risk in a large multicentre cohort of PWH in the USA & may lead to failure to prescribe statins to PWH unless guidelines change.
🔗 ow.ly/U7iG50X8kez
Matt Durstenfeld, MD MAS retweeted
Heart failure is a major contributor to the global burden of cardiovascular disease. It affects more than 55 million people 🫀
A new Lancet Series calls for a reframe—heart failure as preventable chronic disease.
Read this, a linked Editorial, & more 👉 hubs.ly/Q03J4ZtS0
ALT The Lancet, Sept 9 2025 issue. The cover quote: "Heart failure is not inevitable and there are compelling arguments for refocusing attention to prevention Doing so offers substantial potential to reduce the global burden of cardiovascular disease."
Matt Durstenfeld, MD MAS retweeted
📢 Largest study to date of HFimpEF—out in JACC!
🫀 Among >28K new HFrEF patients, 1 in 3 improved to HFimpEF within 12 months
⚠️ Risk remains:
• HF events ↓
• Mortality ↓
• GDMT use declined
🔍 Continuing GDMT is critical.
@ankeetbhatt @ATSandhu
jacc.org/doi/10.1016/j.jacc.…
Matt Durstenfeld, MD MAS retweeted
For people with #HIV, new @AHAScience PREVENT equations predict lower 10 year heart risk than the PCE so fewer will be prescribed statins if widely adopted w/o changing guidelines: validation is needed in this high-risk group! @durstenfeld
Read in #JGIM: buff.ly/h5q3pHd
New pub @JournalGIM : for people w #HIV new @AHAScience PREVENT equations predict ⬇️risk of 🫀events than older pooled cohort equations (which underestimate risk), would result in fewer statin prescriptions if adopted. Urgently need calibration study 4 PWH link.springer.com/article/10…
Matt Durstenfeld, MD MAS retweeted
UCSF scientists had a hypothesis: What if lingering bits of the coronavirus were causing debilitating long COVID symptoms? trib.al/o74dXkb
Matt Durstenfeld, MD MAS retweeted
Contribute to the Long COVID and Post-Acute Infection Syndromes discussion! Submit abstracts and scholarships by May 13, 11:59 PM MST. Hear @MichaelPelusoMD and top experts in infectious disease and immunology. Act now: hubs.la/Q03llG180! #KSLongCOVID26 #LongCOVID
This is terrible: NIH to end billions of dollars in foreign research grants nature.com/articles/d41586-0…
Matt Durstenfeld, MD MAS retweeted
To counter pill-burden, a major barrier to HF GDMT adherence, polypills are being investigated. In this #ACCSimPub the authors developed polypill prototypes & manufacturing pathways w/pharmacy partners. Clinical trials are underway to study this strategy.🔗bit.ly/4hQDbty
Matt Durstenfeld, MD MAS retweeted
"no one has died" because of feeding USAID to the woodchipper, Elon claimed. In this devastating piece the NYT went out and learned some of their names and stories:
❗️New paper: does a cardiologist clinic visit prevent cardiovascular events for people w #HIV without known 🫀disease?
see what our team found in the @NIMHD funded PATHWAYS study here: ahajournals.org/doi/full/10.… @hivcardiodoc @DCRINews @UCSFCardiology
Matt Durstenfeld, MD MAS retweeted
Yes, the US government has been subsidizing science. That is not a weakness of our system. It is one of our greatest strengths. Turning our back on NIH and the institutions who do science for the sake of science, not profit, debases us all.
Matt Durstenfeld, MD MAS retweeted
NIH just made a drastic change to indirect cost rates, reducing the rate to 15%, a significant cut from the 60%+ some institutions charge. This will have a devastating effect on the nation’s medical research infrastructure. @ResearchAmerica @AAMC @YaleMed grants.nih.gov/grants/guide/…
Matt Durstenfeld, MD MAS retweeted
James N. Kirkpatrick, MD, FACC, a leader in echocardiography, a gifted mentor and teacher, and a pioneer in the field of medical ethics, passed away unexpectedly on Jan. 1. Read more about his life and contributions to cardiology with reflections from ACC leaders: bit.ly/4h72jMF
Matt Durstenfeld, MD MAS retweeted
It is with immense sadness that we announce a dedicated ASE and #ASEFoundation champion, James Kirkpatrick, passed away yesterday. He was a highly respected colleague & mentor. His devotion to his patients & the #EchoFirst field will be greatly missed. bit.ly/49Z9rsd
❗️New Paper: HIV‐Associated Heart Failure: Phenotypes and Clinical Outcomes in a Safety‐Net Setting: #HIV associated w⬆️risk of 🪦 among people with #HF 🫀ahajournals.org/doi/10.1161/… @JAHA_AHA @AHAScience @UCSFCardiology @ZSFGCare
Matt Durstenfeld, MD MAS retweeted
Key stakeholders perceive a HFrEF polypill to be a highly acceptable, feasible, and appropriate strategy to improve care of HFrEF patients @WashUCardiology @WUDeptMedicine @durstenfeld @colettedejong #AHAJournals
ahajrnls.org/4hZpKbZ
Matt Durstenfeld, MD MAS retweeted
Our mechanistic review of #LongCovid - published in @CellCellPress - hopefully will be helpful coming out of the very inspiring RECOVER-Treating Long COVID meeting this week.
Excited for the progress we will make together in the next year!
sciencedirect.com/science/ar…