MD-PhD, researcher in ADHD, Psychiatry resident @PittPsychiatry

Joined February 2020
Douglas Leffa retweeted
Looking forward to the Pascoal team’s presentations at this Saturday’s #AIC pre-conference! @NeuroimagingPIA @ISTAART @alzassociation Check out our line-up: – at Philadelphia, PA
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Douglas Leffa retweeted
Congratulations to @BellaverBruna for receiving the Publication of the Year Award from the Biofluid Based Biomarkers @ISTAART Professional Interest Area at PIA day, for her recent paper in Nature Medicine! #AAIC24 – at Philadelphia, PA
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Very proud to share this one! Here we showed transcriptomic similarities and differences between three AD animal models and EOAD and LOAD. Thank you all to collaborators involved @giovannacollar @erzimmer @mvlourenco @aslfricardo @TharickAPascoal @pedrorosaneto
🚨ONLINE NOW! In our new article led by @BellaverBruna and #DeBastiani published in @iScience_CP, we took advantage of comparative medicine tools to investigate molecular core similarities and differences among AD mouse models and EOAD and LOAD individuals tinyurl.com/3fj8b8tb
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Amazing work by the great @jpfsouza33 !
Out now in Neurobiology of Aging! In this new article, we demonstrated that vascular risk burden & AD pathophysiology jointly accelerate neurodegeneration and cognitive decline in CU individuals @erzimmer @ufrgsnoticias @ppgbioq @CAPES_Oficial @TharickAPascoal @LabPascoal
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Please join us in welcoming new faculty members Bruna Bellaver, PhD (Research Assistant Professor of Psychiatry), and Pamela Lukasewicz Ferreira, PhD (Research Assistant Professor of Psychiatry)! bit.ly/3SeYaNE
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Research from Pitt's School of Medicine may hold the key to understanding Alzheimer's progression. Read more about this groundbreaking study. pittmag.pitt.edu/news/advanc…
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A link between #ADHD and #Alzheimers disease has been suspected for some time, and now two separate #research studies have shown a #connection. Find out more ➡️ bit.ly/3KrQnHD.
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What an amazing experience at #AAIC23! Thanks a lot for the @alzassociation @ISTAART for the opportunity to share our work from @LabPascoal 🇺🇸 & @zimmerneurolab 🇧🇷. Already excited to see you all again in Philly #AAIC24 🧠
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Amazing @jpfsouza33 !
Congrats to our PhD student @jpfsouza33 for receiving the Prof. Gilberto Schwartsmann Award for publishing the best paper in 2022-23 (rdcu.be/dhOJk) among the medical students at @ufrgsnoticias! Huge team effort led by João together with @LabPascoal & @zimmerneurolab 👏
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Any program would be lucky to have you!
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Douglas Leffa retweeted
We are happy that @dtleffa's work linking ADHD with Alzheimer's is being featured in numerous TV broadcasts across the country, reaching millions of Americans wgem.com/2023/07/24/brain-co…
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Douglas Leffa retweeted
We thank the @alzassociation and are very proud of our postdocs @gbnegrini and @SarahAbbas52 awarded with the AA Research and Clinical fellowships, respectively. They will address important gaps in tau PET harmonization and the use of inflammation biomarkers in trials. Congrats!!
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Douglas Leffa retweeted
What a fantastic talk by @guilhermepovala at #AIC23, where he discussed the impact of microglial activation on brain atrophy in preclinical AD. #AAIC2023 @alzassociation @ISTAART
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Douglas Leffa retweeted
During the coffe break don’t miss the opportunity to check the beautiful poster of @FrancieliRohden where she evaluated the association between astrocyte reactivity and synaptic distinction!! #AAIC2023 @alzassociation
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Douglas Leffa retweeted
Fantastic presentation by @dtleffa where she showed that the individuals with ADHD and cognitive impairment may have a more severe disease phenotype. #AAIC2023
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Amazing work by @BellaverBruna !!
Replying to @LabPascoal
By assessing more than 1,000 CU participants, we observed that plasma p-tau181 increases as a function of Aβ only in individuals that present positive astrocyte reactivity biomarker signature (Ast+). The presence of both A+/Ast+ showed a large magnitude of effect on p-tau levels.
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Amazing work from @jpfsouza33 ! You will shape the Alzheimer’s field, my friend!
Our latest work is out in @ScienceAdvances🚨! Using multiple PET radiotracers, we found clinical evidence that APOEε4 contributes to microglial activation in early Braak regions, which is further associated with AD progression 🧠. Link: science.org/doi/10.1126/scia…
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Douglas Leffa retweeted
This morning @BellaverBruna presented her results on how kidney function impacts plasma p-tau levels, mainly in cognitively unimpaired individuals. If you missed it, her presentation is also available on-demand! @adpdnet #ADPD2023 #adpd23
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Douglas Leffa retweeted
@BellaverBruna work "BLOOD-BRAIN BARRIER PERMEABILITY IMPACTS THE PERFORMANCE OF PLASMA AMYLOID-B" can be found in the poster hall by the number 329.#ADPD2023 @adpdnet
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