David Shaywitz (@DShaywitz) header
David Shaywitz (@DShaywitz) profile picture

Physician-scientist | Chief Medical Scientist, Lore : Agency + health | Advisor: Biopharma R&D + health technology | HMS DBMI | AEI

Boston
Joined October 2011
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“I've lost close family members to cancer that didn't yet have treatments available, the hardest part for them wasn't affording it. A lack of innovation is access problem we often overlook because it isn't as salient-but it is a far larger barrier than price.” - @C_Garthwaite
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Something’s def in SF air… 1. On IPO roadshow, Anthropic ceo anticipates AI-mediated cures for AD, cancer, etc in next 10y 2. VC a16z (an investor) described Counsel Health acquisition by Oura as -> “high-quality, abundant, personalized, & proactive pt care” @matthewherper
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Setting an unattainable objective. I wish it would come true, but curing all these diseases in the next 10 years is impossible. And I'm very optimistic about the impact of AI for improving health.
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In short, Oura acquisition of Counsel strikes me, sadly, as another win for algorithm-driven decomposition of health & for worshipping at alter of numeric optimization, another setback for relational health & care concerned w understanding & aligning w individual’s values
Vision of @CounselHealth, as I wrote for @timmermanreport in Feb... Presumably in acquiring Counsel, @ouraring mgmt also evidently believes that future of medicine belongs to the machines.... (I had thoughts in recent @WSJ op-ed, just before IPO pulled wsj.com/opinion/when-ai-tell…)
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Vision of @CounselHealth, as I wrote for @timmermanreport in Feb... Presumably in acquiring Counsel, @ouraring mgmt also evidently believes that future of medicine belongs to the machines.... (I had thoughts in recent @WSJ op-ed, just before IPO pulled wsj.com/opinion/when-ai-tell…)
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Just finished listening to absolutely captivating bk abt society, culture, networks, science, traits, & humanity, discussed not only w remarkable erudition (as you'd expect) but also w curiosity & deeply-felt empathy; just loved it; kudos, @NAChristakis! audible.com/pd/Blueprint-Aud…
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Replying to @davidshor
@davidshor For decades I’ve heard discussion of how Israel might balance being Jewish state & democracy if/as demographics shift. I’ve started to wonder more recently abt impact (as you’ve highlighted) of differential birth rates in v religious v more secular Jews. @SethAMandel
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2/Setting the stage: everyone wants to know how AI will play out in their domain, and no one actually knows (confident predictions aside); we're likely at "frenzy" stage in Carlota Perez's model of tech revolutions...
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... is what every single person in New England watching this afternoon's devastating game is thinking...
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Wow 🤩 - look at the lines outside of the Jewish owned eateries being boycotted today by the “Free Palestine” crowd in Philadelphia! Am Israel Chai.
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Actually disagree, @bijans -certainly not fan of clickbaity headline. Data suggest having genetic markers improves POS 2-3x. Given 9/10 drugs entering clin dev fail, you can improve odds AND still fail (in fact - based on maths - you prob will). @JackScannell13 @matthewherper
The humbling woodchipper of biology - good piece by @matthewherper
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Here's a slide I made for a talk on AI in R&D a few weeks ago (design executed by ChatGPT) on causal bio. I also touched on these trials recently in @WSJ oped-> wsj.com/opinion/when-ai-tell…. And also discussed in @timmermanreport timmermanreport.com/2026/08/…
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Replying to @jflier
Harvard Medical School panel: “panelists scorned the idea that obesity is a serious medical problem and framed efforts to treat it as examples of racism and oppression. According to panelist Da’Shaun L. Harrison, the weight-loss drug GLP-1 is “a fascistic tool to eradicate fatness” wsj.com/opinion/free-express…
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1/3 Latest ep of @NEJM_AI Grand Rounds, feat @mnedoszytko @AbridgeHQ just so good. Fav quote: "You need to live the health care system in order to understand it, because nothing in theory translates into that work." podcasts.apple.com/us/podcas… @AndrewLBeam @arjunmanrai @zakkohane
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2/3 I also really appreciated this @mnedoszytko quote, capturing amazing healthtech innovation environment in US where everyone is building, and failure "just part of process of learning" (vs career catastrophe as seems to be case elsewhere).
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Excellent lede from @GlobeChadFinn re: @TomBrady as broadcaster: “Fans of 30 other NFL franchises can be excused if they didn’t foresee Tom Brady getting better in the broadcast booth.” Here in New Engl, we’re delighted not surprised. bostonglobe.com/2026/11/07/s… @NFLonFOX @Patriots
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