@drtomround

GP @BBB_health AcademicCL @NIHRresearch @KingsMedicine Assoc Editor @BJGPJournal @rcgp ;exTrustee @Barts_Charity https://xitter.cf/t.co/BWcZwjjGBy

 London
Joined October 2010
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841Media
Replying to @TomHCalver
Read your article - I’m an NHS GP - the point of your article should have been that increasing access DOES NOT equate to more capacity. With no new funding we can’t employ more Dr’s so no more appointments - rearranging deckchairs on the titanic springs to mind - not GP fault
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Paul Sax@PaulSaxMDOct 10
PowerPoint deadline season in academic medicine, w/ an inbox overflowing with "friendly reminders" to submit slides and other stuff weeks before my talks! Naturally, instead of finishing those slides, I wrote this to complain about it. Free link in replies. @NEJM
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NEJM
@NEJMOct 10
Original Article: Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis (NHS-Galleri trial) nej.md/4xRZN5L Editorial: A Step in the Search for the Elusive Holy Grail of Early Detection of Cancer nej.md/4cK3UIy #Oncology #Genetics
Bar chart comparing detection methods of two groups, Intervention Group (N=3637) and Control Group (N=3400). For the Intervention Group, clinically detected: 2464, MCED-detected: 937, NHS current screening program-detected: 236. For the Control Group, clinically detected: 3110, MCED-detected: 0, NHS current screening program-detected: 290. The colors represent each detection method: green for clinically detected, red for MCED-detected, and yellow for NHS detection.

ALT Bar chart comparing detection methods of two groups, Intervention Group (N=3637) and Control Group (N=3400). For the Intervention Group, clinically detected: 2464, MCED-detected: 937, NHS current screening program-detected: 236. For the Control Group, clinically detected: 3110, MCED-detected: 0, NHS current screening program-detected: 290. The colors represent each detection method: green for clinically detected, red for MCED-detected, and yellow for NHS detection.

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NEJM
@NEJMOct 9
This randomized trial examined whether adding a multicancer early-detection blood test to usual care reduces late-stage cancer diagnoses in adults 50 to 77 years of age. Research findings from the NHS-Galleri trial are summarized in a new Quick Take video. nej.md/4iZFheW
Illustration of a multi-cancer early-detection blood testing kit with a test tube filled with blood, alongside a magnified view of a cancer cell surrounded by other cells.

ALT Illustration of a multi-cancer early-detection blood testing kit with a test tube filled with blood, alongside a magnified view of a cancer cell surrounded by other cells.

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The BMJ
@bmj_latestSep 24
Compared with no use of hormone therapy, oral menopausal hormone therapy was associated with increased venous thromboembolic risk regardless of dosage & treatment duration, finds study. No increased thrombotic risks were observed with transdermal therapy bmj.com/content/394/bmj-2026…
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Great to be part of this trail blazing NHS Galleri RCT of multi cancer early detection (MCED) test . Reduction in late stage 4 at diagnosis and emergency presentations @NEJM qmul.ac.uk/news/latest-news/… @petersasieni @QMUL @QMUL_WIPH_CPDD @CharlesSwanton @richarddneal @kingsmedicine

Major NHS trial provides new evidence on multi-cancer blood test

Results from the world’s first randomised controlled trial of a multi-cancer early detection blood test have been published in two leading medical journals, providing important new evidence on...

qmul.ac.uk
NEJM
@NEJMSep 23
Original Article: Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis (NHS-Galleri trial) nej.md/4xRZN5L Editorial: A Step in the Search for the Elusive Holy Grail of Early Detection of Cancer nej.md/4cK3UIy #Oncology #Genetics
Panels A–D are graphs that show the risk of diagnosis of stage III or IV cancer among the 12 prespecified cancer types, of stage IV among the 12 prespecified cancer types; of stage III or IV among all routinely staged cancer types, and of stage IV among all routinely staged cancer types. Panels E and F are bar charts that show the distribution of cancers according to stage and trial group for the 12 prespecified cancer types (post hoc analysis) and for all routinely staged cancer types.

ALT Panels A–D are graphs that show the risk of diagnosis of stage III or IV cancer among the 12 prespecified cancer types, of stage IV among the 12 prespecified cancer types; of stage III or IV among all routinely staged cancer types, and of stage IV among all routinely staged cancer types. Panels E and F are bar charts that show the distribution of cancers according to stage and trial group for the 12 prespecified cancer types (post hoc analysis) and for all routinely staged cancer types.

Bar chart comparing detection methods of two groups, Intervention Group (N=3637) and Control Group (N=3400). For the Intervention Group, clinically detected: 2464, MCED-detected: 937, NHS current screening program-detected: 236. For the Control Group, clinically detected: 3110, MCED-detected: 0, NHS current screening program-detected: 290. The colors represent each detection method: green for clinically detected, red for MCED-detected, and yellow for NHS detection.

ALT Bar chart comparing detection methods of two groups, Intervention Group (N=3637) and Control Group (N=3400). For the Intervention Group, clinically detected: 2464, MCED-detected: 937, NHS current screening program-detected: 236. For the Control Group, clinically detected: 3110, MCED-detected: 0, NHS current screening program-detected: 290. The colors represent each detection method: green for clinically detected, red for MCED-detected, and yellow for NHS detection.

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Nature Medicine
@NatureMedicineSep 23
New studies provide evidence on performance, safety & implementation of the #Galleri multi-cancer early detection test, underscoring the next challenge: demonstrating population-level benefit. Catherine Marinac & colleagues @DanaFarber discuss the data: dlvr.it/TVcDl0

Some answers, more questions for multi-cancer early detection tests

Nature Medicine - The PATHFINDER 2 and NHS-Galleri studies provide complementary evidence on the clinical performance, safety and implementation of multi-cancer early detection, while underscoring...

nature.com
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GRAIL
@GrailBioSep 22
Detailed peer-reviewed results from the NHS-Galleri trial are now published in @NEJM and @NatureMedicine, providing clinical utility and performance data. These results reflect GRAIL’s commitment to setting a high bar for MCED evidence—rigorously demonstrating Galleri’s potential to reduce late-stage diagnoses and find more cancers earlier. #EarlyCancerDetection #CancerScreening #MCED Learn more: New England Journal of Medicine: bit.ly/3Vbd5f8 Nature Medicine: bit.ly/4y9il1j Rx Only. See Important Safety Information: bit.ly/411L6zk
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NEJM
@NEJMSep 22
In a trial of a blood-based multicancer early-detection test added to usual care, the incidence of stage III or IV cancer after three rounds of screening did not differ significantly from that with usual care alone. Full NHS-Galleri trial results: nej.md/4xRZN5L Editorial: A Step in the Search for the Elusive Holy Grail of Early Detection of Cancer nej.md/4cK3UIy
A bar chart from an Original Article published in the New England Journal of Medicine article titled "Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis." The chart shows the distribution of the route to cancer diagnosis according to trial group after three annual screening rounds. The trial name, NHS-Galleri, is in parentheses after the title. The NEJM identity sits at the bottom.

ALT A bar chart from an Original Article published in the New England Journal of Medicine article titled "Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis." The chart shows the distribution of the route to cancer diagnosis according to trial group after three annual screening rounds. The trial name, NHS-Galleri, is in parentheses after the title. The NEJM identity sits at the bottom.

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The BMJ
@bmj_latestSep 8
The Royal College of General Practitioners has published its first dedicated research strategy, setting out a three year roadmap for 2026-29. But patient engagement, early career exposure, and evolving digital environments are lacking prominence bmj.com/content/394/bmj-2026…

RCGP research roadmap: first steps to strengthen primary care research

Patient engagement, early career exposure, and evolving digital environments need more attention The Royal College of General Practitioners (RCGP) has published its first dedicated research strategy,...

bmj.com
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Queen Mary University of London@QMULAug 19
Air pollution stunts children’s lung growth. New Queen Mary research found that improvements in air quality after the introduction of London’s ULEZ are associated with accelerated lung growth in children. Read more: shorturl.at/Jx86o
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Sadiq Khan
@SadiqKhanAug 19
NEW: An independent study by @QMUL has found that after the ULEZ was introduced, children’s lungs grew faster in central London, and have now caught up with children outside of the capital. Incredible news 💚 theguardian.com/environment/…
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Dr Steve Taylor@DrSteveTaylorJul 15
I calculate that this is extremely risky @CareQualityComm @jamesmurray_ldn @SKinnock @CUH_NHS
@DrKatie.BSky.Social@doctor_katieJul 15
Surgery colleagues! Is this new? Is this a usual response to a Head & Neck 2WW referral?
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The BMJ
@bmj_latestJul 13
Plans to slash £16.7m in funding for clinical academics in universities will be “disastrous” for medical education, the doctors’ union has warned @TheBMA bmj.com/content/394/bmj-2026…

Medical academic funding: Cuts will be “disastrous,” BMA warns

Plans to slash £16.7m in funding for clinical academics in universities will be “disastrous” for medical education, the doctors’ union has warned. The BMA, alongside the British Dental Association,...

bmj.com
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Dr Steve Taylor@DrSteveTaylorJul 2
Most of us will face the reality of end-of-life care — yet our healthcare system treats palliative care as an after thought, funded mainly by charities. Why is something so essential still so undervalued and patchy across the UK? What must change? Full 👇🏻 youtu.be/22BzLBmPL_k?si=mdSI…
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ExplosiveEnema@ExplosiveEnema2Jun 20
Screening for prostate cancer does not save lives Glad he's feeling well, but this is terrible advice from @JeremyClarkson and will result in many men suffering both physically and psychologically If you're concerned, speak to your Doctor... But don't lie to them
The Farmer's Dog
@FamersDogJun 20
An update and a message from Jeremy. “Thank you so much for all the kind messages I've had but now, an announcement.”
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Professor Chris Whitty@CMO_EnglandJun 18
A new study shows HPV vaccination in England has led to the number of deaths from cervical cancer falling to zero in vaccinated women under 25. Please encourage all eligible children to get vaccinated. thelancet.com/journals/lance…
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Eric Topol
@EricTopolJun 15
Yet another study shows a 24% reduced risk of dementia after the Shingles vaccine. This one in over 500,000 participants with a recent skilled nursing facility stay, adding to 4 huge natural experiments in 4 countries (US, Canada, Wales, and Australia) acpjournals.org/doi/10.7326/… @AnnalsofIM
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@DrKatie.BSky.Social@doctor_katieJun 13
There are no words. The whole profession feels Dr Kumar’s grief. We all empathise with this outrageous request. What’s happened to mental health trusts? Where’s the oversight for these failings? It’s happening on a national scale. It’s a silent catastrophe. @CareQualityComm
Dr Sanjoy Kumar
@drsanjoykumarJun 11
Fed up. Just spent 14 weeks at @nottsinquiry didn’t miss a minute as this was all I could do in my daughter Grace’s name against all those who failed. Get to my desk and this is what I’m greeted with……
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ThesalariedGP@zaynhasnJun 11
Every single day GPs have to face BS like this. Secondary care isn’t living up to its end of hospital contracts. Its endemic. Scandal of workload dumps in plain site. “GP to initiate antipsychotic”, my god man. Bring back shame.
Dr Sanjoy Kumar
@drsanjoykumarJun 11
Fed up. Just spent 14 weeks at @nottsinquiry didn’t miss a minute as this was all I could do in my daughter Grace’s name against all those who failed. Get to my desk and this is what I’m greeted with……
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