Addy Deshpande (perspectivist_) (@draditya12) header
Addy Deshpande (perspectivist_) (@draditya12) profile picture

Computational biologist. Wannabe photographer. Baseball and Science. Yankees fan. NYC. All opinions are mine alone.

New York, USA
Joined November 2010
Photo by Addy Deshpande (perspectivist_) (@draditya12)Photo by Addy Deshpande (perspectivist_) (@draditya12)Photo by Addy Deshpande (perspectivist_) (@draditya12)Photo by Addy Deshpande (perspectivist_) (@draditya12)Photo by Addy Deshpande (perspectivist_) (@draditya12)
Addy Deshpande (perspectivist_) retweeted
Preprint on "Finding easy regions for short-read variant calling from pangenome data": arxiv.org/abs/2507.03718
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Addy Deshpande (perspectivist_) retweeted
🚀 Exciting to see our work @sloankettering on bringing WGS to pediatric cancer patients featured on the @Newsweek cover! With @carisls & @TempusAI now launching commercial WGS for myeloid leukemias, the future is clear: WGS for every cancer patient is coming. 🧬
Whole #genomesequencing, a process which is used widely to improve treatments of difficult-to-diagnose diseases as well as for genetic screening of newborns, has given hope to patients with certain rare #cancers. In a feature for @Newsweek, MSK scientists and doctors, including @PapaemmanuilLab, a computational oncologist at MSK, reveal how genes are mapping cures for cancer. "For many cancer types, outcomes have completely changed," Dr. Papaemmanuil says. "We have seen tumor types that were incurable now be cured without even giving them chemotherapy." Read more here: bit.ly/4hJiiRB bit.ly/4hJiiRB
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Addy Deshpande (perspectivist_) retweeted
All Rise for the August AL Player of the Month 👨‍⚖️ Congratulations, @TheJudge44 👏
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Its all going down hill (I know I could have made a Gil pun but refuse to! Yankees are in trouble!)
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Addy Deshpande (perspectivist_) retweeted
Judge having a decent year
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Addy Deshpande (perspectivist_) retweeted
A 406 ft out with the game on the line is nuts
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Addy Deshpande (perspectivist_) retweeted
New @medrxivpreprint, "Unearthed Novel Molecular #Phenotypes & Potential Therapeutic Targets in Esophagogastric #Adenocarcinoma," by @WCMCPathology's @AWindonMD, @MajdAssaad, @emh9016, @asbonerw, @PPJessurun, Drs. Justin Mclee, Juan Miguel Mosquera, et al. medrxiv.org/content/10.1101/…
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Addy Deshpande (perspectivist_) retweeted
The Yankees whole infield is question marks
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Addy Deshpande (perspectivist_) retweeted
lol who did this
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Addy Deshpande (perspectivist_) retweeted
A major problem with cell-free tumor DNA to detect cancer (Liquid biopsy) is its very low quantity. Today @NatureMedicine use of #AI to overcome that issue with impressive results for radical signal-to-noise enrichment nature.com/articles/s41591-0… free access rdcu.be/dKNOx
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Addy Deshpande (perspectivist_) retweeted
MRD-EDGE is out today in @NatureMedicine! Thrilled to see this in print when the future for #ctdna in plasma whole genome sequencing is brighter than ever.
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Addy Deshpande (perspectivist_) retweeted
New paper! New lovely write up! Same love of colored pens….
An artificial intelligence-powered method for detecting tumor DNA in blood has shown unprecedented sensitivity in predicting cancer recurrence, says a team led by Dr. Dan Landau (@landau_lab) and researchers at @nygenome and @MSKCancerCenter. bit.ly/45pXCJ3
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Amazing to see a real world application of our algorithm, dryclean, in MRD-EDGE.🙌🏽. Congratulations @landau_lab, @adamjwidman and team! Shoutout to @skimomiks
Replying to @landau_lab
With @skimomiks help, we also improved our signal de-noising in CNV tumor-informed cfDNA detection, and added a critical new module based on subtle BAF skews, delivering ultra-sensitive detection with as little as 200Mb of aneuploidy.
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Addy Deshpande (perspectivist_) retweeted
Sweep, Sweep, Victory. Presented by @Delta #DeltaCleanSweep
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Addy Deshpande (perspectivist_) retweeted
Congrats to @MatLegut & the entire @OverT_Bio team! Grateful for the opportunity to translate discoveries from our lab @nygenome & @nyuniversity into therapies for cancer patients. Thrilled to be a part of this amazing team — onward and upward! 🚀
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Addy Deshpande (perspectivist_) retweeted
Best advice I ever got: think like a VC when looking for tech job. It led me to joining Rippling ($11B+) before its Series A. It changed my life, so I built a free tool to help others. We expect that each company listed on Prospect will grow at least 2X over the next 4 years:

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Addy Deshpande (perspectivist_) retweeted
Our most complex biologic system—immunity—is reviewed in 3 new @CellCellPress papers, open-access Adaptive cell.com/cell/fulltext/S0092… Innate cell.com/cell/fulltext/S0092… New insights cell.com/cell/fulltext/S0092… @RMedzhitov
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