Clinical AI Architect and Pharmacologist. Internal Med, Geriatrics Physiatrist, Bioastronautics Researcher

Alicante, Spain
Joined November 2015
Dr. Marie Gabrielle Laguna Arismendi retweeted
CEO of Coinbase sends out catastrophic message this morning. 1. Laid off over 2,000 people. This message to laid off people was written using AI. 2. Code being pushed to prod is vibe coded. He admits that. That is absolutely terrifying.
This is an email I sent earlier today to all employees at Coinbase: Team, Today I’ve made the difficult decision to reduce the size of Coinbase by ~14%. I want to walk you through why we're doing this now, what it means for those affected, and how this positions us for the future. Why now Two forces are converging at the same time. We need to be front footed to respond to both. First, the market. Coinbase is well-capitalized, has diversified revenue streams, and is well-positioned to weather any storm. Crypto is also on the verge of the next wave of adoption, with stablecoins, prediction markets, tokenization, and more taking off. However, our business is still volatile from quarter to quarter. While we've managed through that cyclicality many times before and come out stronger on the other side, we’re currently in a down market and need to adjust our cost structure now so that we emerge from this period leaner, faster, and more efficient for our next phase of growth. Second, AI is changing how we work. Over the past year, I’ve watched engineers use AI to ship in days what used to take a team weeks. Non-technical teams are now shipping production code and many of our workflows are being automated. The pace of what's possible with a small, focused team has changed dramatically, and it's accelerating every day. All of this has led us to an inflection point, not just for Coinbase, but for every company. The biggest risk now is not taking action. We are adjusting early and deliberately to rebuild Coinbase to be lean, fast, and AI-native. We need to return to the speed and focus of our startup founding, with AI at our core. What this means To get there, we are not just reducing headcount and cutting costs, we’re fundamentally changing how we operate: rebuilding Coinbase as an intelligence, with humans around the edge aligning it. What does this mean in practice? - Fewer layers, faster decisions: We are flattening our org structure to 5 layers max below CEO/COO. Layers slow things down and create coordination tax. The future is small, high context teams that can move quickly. Leaders will own much more, with as many as 15+ direct reports. Fewer layers also means a leaner cost structure that is built to perform through all market cycles. - No pure managers: Every leader at Coinbase must also be a strong and active individual contributor. Managers should be like player-coaches, getting their hands dirty alongside their teams. - AI-native pods: We’ll be concentrating around AI-native talent who can manage fleets of agents to drive outsized impact. We’ll also be experimenting with reduced pod sizes, including “one person teams” with engineers, designers, and product managers all in one role. In short: AI is bringing a profound shift in how companies operate, and we’re reshaping Coinbase to lead in this new era. This is a new way of working, and we need to leverage AI across every facet of our jobs. To those who are affected I know there are real people behind these decisions — talented colleagues who have poured themselves into this company and our mission. To those of you who will be leaving: thank you. You’ve helped build Coinbase into what it is today, and I am sincerely grateful for everything you've done. All impacted team members will receive an email to their personal account in the next hour with more information, and an invitation to meet with an HRBP and a senior leader in your organization. Coinbase system access has been removed today. I know this feels sudden and harsh, but it is the only responsible choice given our duty to protect customer information. To those affected, we will be providing a comprehensive package to support you through this transition. US employees will receive a minimum of 16 weeks base pay (plus 2 weeks per year worked), their next equity vest, and 6 months of COBRA. Employees on a work visa will get extra transition support. Those outside of the US will receive similar support, based on local factors and subject to any consultation requirements. Coinbase prides itself on talent density. Our employees are among the most talented people in the world, and I have no doubt that your skills and experience will be highly sought after as you pursue your next chapters. How we move forward To the team that is staying, I know this is a difficult day. We’re saying goodbye to colleagues and friends you've been in the trenches with. But here’s what I want you to know as we move forward together: Over the past 13 years, we have weathered four crypto winters, gone public, and built the most trusted platform in our industry. We’ve made it this far by making hard decisions and by always staying focused on our mission. This time will be no different – nothing has changed about the long term outlook of our company or industry. And most importantly, our mission has never been more important for the world. Increasing economic freedom requires a new financial system, and we’re building it. The Coinbase that emerges from this will be more capable than ever to achieve our mission. Brian
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Dr. Marie Gabrielle Laguna Arismendi retweeted
This great blog, Understanding LLMs from Scratch in easy language. - medium.com/data-science/unde…
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Dr. Marie Gabrielle Laguna Arismendi retweeted
As an M.D. and cloud engineer with a post-grad in ComSci, my team and I have built a new kind of cybersecurity service combining AI-powered analysis with expert human verification to protect your business. Learn more at eurawest.com #Cybersecurity #AI #CloudComputing
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Dr. Marie Gabrielle Laguna Arismendi retweeted
The NIS2 Directive is raising the bar for cybersecurity in the EU. Discover 10 essential actions you need to take now to ensure compliance and avoid costly penalties.

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Dr. Marie Gabrielle Laguna Arismendi retweeted
Opinión impopular: Tu 'fórmula secreta' debería ser tu herramienta de marketing #1. Si tienes miedo de compartirla, no confías en su valor. #Transparencia #Negocios bit.ly/4fgwpO8
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Hot take: Your 'secret sauce' should be your #1 marketing tool. If you're afraid to share it, you're not confident in its value. #Transparency #Business bit.ly/4fgwpO8
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Just dropped my first newsletter with 3 common mistakes Costa Blanca businesses make. Are you guilty of Mistake #2 (having no lead capture system)? It's like having a shop with no cash register. Link in bio to subscribe. #LocalBusiness bit.ly/3JaqsGk
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Acabo de lanzar mi primer newsletter con 3 errores comunes que cometen los negocios de la Costa Blanca. ¿Eres culpable del Error #2 (no tener un sistema de captura de leads)? Es como tener una tienda sin caja registradora. Enlace en la bio para suscribirte. #NegocioLocal
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Dr. Marie Gabrielle Laguna Arismendi retweeted
My secret weapon isn't a secret. It's an architecture. Local strategy + global execution. It's how you deliver world-class results without world-class overhead. #BusinessModel #Scalability bit.ly/4l9sxzV
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Dr. Marie Gabrielle Laguna Arismendi retweeted
The old sales model is dead. Stop trying to close. Start trying to help. The most successful businesses add massive value before ever asking for the sale. #BusinessStrategy #Trust bit.ly/3JaqsGk
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Dr. Marie Gabrielle Laguna Arismendi retweeted
El viejo modelo de ventas ha muerto. Deja de intentar cerrar. Empieza a intentar ayudar. Los negocios más exitosos añaden un valor inmenso antes de pedir la venta. #EstrategiaDeNegocio #Confianza bit.ly/3JaqsGk
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Estás construyendo un negocio que pueda sobrevivirte? La prueba definitiva de un fundador es crear algo que perdure. #Legado #Negocios bit.ly/4lU8Wol
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Are you building a business that can survive you? The ultimate test of a founder is creating something that lasts. #Legacy #Business bit.ly/4lU8Wol
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Tus primeros clientes son tus mejores consultores. Escúchalos. #ClientePrimero bit.ly/4lVa7UJ
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Your first customers are your best consultants. Listen to them. #CustomerFirst bit.ly/4lVa7UJ
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Stop chasing followers. Start obsessing over your first 10 customers. They are your focus group, your marketing team, and your proof of concept. #CustomerFocus #Startups bit.ly/4lVa7UJ
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Deja de perseguir seguidores. Obsesiónate con tus primeros 10 clientes. Son tu focus group, tu equipo de marketing y tu prueba de concepto. #FocoEnElCliente #Startups"bit.ly/4lVa7UJ
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Dr. Marie Gabrielle Laguna Arismendi retweeted
¿Le tiene miedo el mundo startup a la palabra 'beneficio'? #Negocios bit.ly/45tPwRl
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Dr. Marie Gabrielle Laguna Arismendi retweeted
Is the startup world afraid of the word 'profit'? #Business bit.ly/45tPwRl
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Dr. Marie Gabrielle Laguna Arismendi retweeted
El beneficio no es codicia. Es el combustible para tu misión. Un negocio sin un camino hacia el beneficio es un hobby con fecha de caducidad. #Rentabilidad #Emprendedor bit.ly/45tPwRl
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