Prof of Surgical Oncology @UofGlasgow & @grisurgery. Precision Medicine & Artificial Intelligence for #PancreaticCancer @precisionpanc @Pancaim_H2020 @IcgcArgo
Glasgow, Scotland
Joined September 2016
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Huge body of work on morphospatial features of #PancreaticCancer #TME and #CAF from pixel to patient level. Please take a look at preprint!
Prof David K. Chang retweeted
#AACR26 Late breaking abstract
Daraxonrasib plus chemotherapy (CT) as first-line (1L) treatment for patients (Pts) with metastatic #PancreaticCancer (mPDAC)
aacrjournals.org/cancerres/a…
@CentralParkWMD @DrShubhamPant
@RevMedicines
Prof David K. Chang retweeted
#AACR26 late breaking abstract on early data from 1st line Daraxonrasib monotherapy in #PancreaticCancer
>90% disease control rate
aacrjournals.org/cancerres/a…
@EileenMOReilly @GarridoLagunaMD @DrShubhamPant
@RevMedicines
Prof David K. Chang retweeted
🚨🚨🚨
RASOLUTE-302 Ph3 is POSITIVE
"Daraxonrasib demonstrated a median OS of 13.2 months versus 6.7 months for chemotherapy, with a hazard ratio of 0.40 (p < 0.0001)".... WOW!
AMAZING news for patients with #PancreaticCancer
The RAS Revolution is ON!!
ir.revmed.com/news-releases/…
Prof David K. Chang retweeted
New preprint from @dkfchang @UofGCancerSci:
Morpho-spatial profiling of cancer-associated fibroblasts reveals architectural subtypes of #PancreaticCancer
biorxiv.org/content/10.64898…
Morphology 🤝 Biology
Super proud of work done by @adam__bryce and the team!
Excited to share our preprint!
Morphospatial profiling of cancer-associated fibroblasts reveals architectural subtypes of pancreatic ductal adenocarcinoma
doi.org/10.64898/2026.02.06.…
Key takeaways 🧵⬇️
@dkfchang @stephan_dreyer @fiekefroeling @LeQuesneLab @UofGCancerSci @CRUK_SI
Prof David K. Chang retweeted
🚨Registration is now open for the Cancer Research UK Pancreatic Cancer Conference 2026!🚨
Join me and my conference co-chairs @Aiims1742 @SaurLab for the inaugural meeting in London, UK, from 7-9 July 2026, hosted by @CR_UK. 💜
Find out more: cruk.ink/47nQbDL
📢Registration is now open for the @CR_UK #PancreaticCancer Conference in London 7th-9th July 2026! Co-organised by our Co-lead @BiffiGiulia, this event is designed to unite researchers and industry experts to accelerate progress in pancreatic cancer research💜. 👉Link in comment
Well done Adam!!! Excellent work!!!
Inspiring meeting and great opportunity to share our work in Boston! #AACRPan25 @AACR @CRUK_SI @UofGMVLS
Prof David K. Chang retweeted
Inspiring meeting and great opportunity to share our work in Boston! #AACRPan25 @AACR @CRUK_SI @UofGMVLS
Prof David K. Chang retweeted
Dr. @dkfchang and colleagues provide in vitro evidence of a novel therapeutic strategy to overcome acquired resistance to PARP inhibitor and platinum in #PDAC, using sequential exposure to ceralasertib and olaparib.
💡 Learn more: go.nature.com/3Zdg06k
Prof David K. Chang retweeted
I’m delighted to have been elected @RoyalSocEd President from April 2025. I’m grateful to the Fellows of the RSE for their support. Looking forward to working with you in the coming years, and further extending our collaborations in Scotland, the U.K. and at international level.
📢 Anton Muscatelli (@UofGVC) has been elected as RSE President 🎉 Sir Anton will take over the role at the RSE on 1 April. Since 2009, he's served as Principal and Vice Chancellor @UofGlasgow – earlier this year he announced his retirement from the role in autumn 2025.
Prof David K. Chang retweeted
😀I was wondering when this would come out - this is so exciting‼️
🤔I know some may say this is a rare population, and it is
👉🏼BUT a ~40% response in >=2nd line #PancreaticCancer is still very, very clinically meaningful👏🏼
🙏🏼AND - we HAVE TO remember to test for this🧬🧬🧬🧬🧬🧬
Prof David K. Chang retweeted
Please listen to the debate and make sure you know the symptoms of #pancreaticcancer. It might save your life.
👏 to all who advocate and research earlier detection and treatment methods.
@nigeljamieson
@precisionpanc
@dkfchang
@LabSpatialNBJ
@lgoodbu
scottishparliament.tv/meetin…
Prof David K. Chang retweeted
This Giving Day, we're proudly supporting cancer research at UofG ❤️
Hear from Prof Chris Halsey, who shares what impact philanthropic support can have for @UofGCancerSci, providing world-class treatment for patients & representing Glasgow as a leader in cancer research in the UK & globally 🌍
glasgow.givingday.co.uk #GlasgowGives @UofG_Alumni
Can’t agree more ❤️
First person profile of @EileenMOReilly @MSKCancerCenter in @JournalCancer
An exceptional and caring oncologist, and a colleague all of us in the #PancreaticCancer research community are lucky to have.
acsjournals.onlinelibrary.wi…
@GABOUALFA
tic work Russell, Hollie and the team!
International Oesophagogastric TNT Group presentation today by @MissHClements at #ESMO24
N=140 pts from 🇬🇧🇺🇸🇨🇦🇺🇦🇱🇹
Total Neoadjuvant FLOT( 8 cycles) can be delivered safety & shows encouraging survival outcomes despite the advanced stage of the patient cohort
@myESMO
Prof David K. Chang retweeted
Shoutout to @Aiims1742 during @JulieFleshman’s remarks at @PanCAN Scientific Summit. One of our very first grantees who’s now an amazing mentor and leader in the field 💜
Prof David K. Chang retweeted
New paper in @Gut_BMJ from @FredrikThege & colleagues @MDAndersonNews, just in time for #AACRPan24:
Metabolic reprogramming by mutant GNAS creates an actionable dependency in intraductal papillary mucinous neoplasms of the pancreas
gut.bmj.com/content/early/20…