🇦🇺🇨🇦Lab Head @MonashBDI @VicHeartInst|Director @atheroaussie| Atherosclerosis,Obesity,macrophage inflammation| #macrophage_yogi|#positive_mentor| my opinion
Melbourne, Victoria, Australia
Joined January 2014
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👇🏽Research @NatMetabolism rdcu.be/b7N6d
An inflammatory gene, RIPK1, increases obesity risk.
Our follow-up intervention study @IMBatUQ also shows promise...watch this space for more updates! 👍🏽
#obesity #genetics #RIPK1 #inflammation
@UQ_News @HeartInstitute
A Queensland scientist is leading a world study that uncovered an inflammatory gene responsible for obesity. Blocking the gene could stop weight loss in its tracks, helping millions of Australians. 7NEWS.com.au @BrittanyCLane #7NEWS
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
Macrophages can engulf targets whole (phagocytosis) or nibble them in small fragments (trogocytosis), a decision controlled by cortical tension in the targets (high tension favors former, low latter)
nature.com/articles/s41556-0…
nature.com/articles/s41556-0…
@NatureCellBio @UCBerkeley
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
What if the future of treating heart disease could be a 'one-and-done' therapy?
A first in human gene-editing study, led by @ProfSNicholls, showed a reduction in LDL by up to 50% and triglycerides by 55% - with a single infusion.
🎥 Watch @AHAScience tv: lnkd.in/g5h2Pv3w
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
🚨 Our new publication in Nature Communications!
Macrophage WDFY3 protects against autoimmunity by boosting efferocytosis and dampening T cell activation.
🛡️ A safeguard for immune homeostasis.
nature.com/articles/s41467-0…
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
Abstract submission is open for our annual scientific meeting!
Submit via: app.oxfordabstracts.com/stag…
Great writing tips for students #positive_mentor
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
Reminder that our obsession with journal names as a lazy proxy for "impact" is new.
Here are the key papers that led to the GLP-1 Lasker Award for Svetlana Mojsov:
Mojsov et al JBC 261:11880 1986
Mojsov et al JCI 79:616 1987
Mojsov et al JBC 265:8001 1990
Journal of Biological Chemistry
Journal of Clinical Investigation
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
In 1928, Alexander Fleming discovered the mould he was working with produced a substance that could kill many common bacteria. He called this new, exciting substance "mould juice". Only after a couple of months did he name it penicillin.
#WorldAntibioticAwarenessWeek
ALT An image of mould grown in a plastic petri dish. The mould is a cream with a grey-green tinge to it and forms in slightly oval shapes.
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
Victorian Heart Institute and Hospital Director @ProfSNicholls is leading world-first trials for genetic high cholesterol, expanding potentially life-saving treatments for those at risk of heart attack and stroke, presented at @American_Heart.
Read: bit.ly/3Zf4IyK
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
Day 2 at @BDI_MDOP #MDO2024 and we have @denujak from @MonashVHI presenting her work on the therapeutic knockdown of the RIPK1 pathway to reduce diet-induced obesity and improve insulin sensitivity 🤩👏🏼
True purpose - ‘what’s next? What can I do?”
Demoted four times and threatened with deportation, 2023 medicine laureate Katalin Karikó's journey in science was difficult but she persevered: "You have to channel all your energy into seeking out 'What's next? What can I do?'"
Listen to her interview: bit.ly/3FcYzbp
ALT A photo copy of a rectangular employee card. On the left is a black and white photo of Katalin Karikó. To the right of the photo is handwritten information in Hungarian.
Well done @emma_solly!! Very well deserved! An excellent talk! 👏🏽👏🏽👏🏽Must be a proud supervisor @jotan80 ❤️
The ECR Rising Star Award Winner at the #AASASM24 was Dr Emma Solly. Congratulations on a fantastic contribution and exciting data. Thanks to CSL for sponsoring our Rising Stars.🌟
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
Our Director & CEO, Prof Elizabeth Hartland AM is among an impressive group of health & medical leaders named Fellows of the Australian Academy of Health & Medical Sciences. Congratulations @ProfHartland! 🥳
#AAHMSFellow @AAHMS_health
Read more here: bit.ly/3YiCuRZ
#AAHMSFellow @Hudson_Research CEO @ProfHartland Professor Elizabeth Hartland's internationally recognised research informs fundamental knowledge of host-pathogen interactions and the development of anti-infective and immune-enhancing therapies that target the infection process.
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
Huge congratulations to our Scientific Head, Prof James Whisstock, on his election as an #AAHMS Fellow for his contributions to the field of #immunology & beyond!
Prof James Whisstock’s discoveries include elucidating the mechanism of function of perforin-like proteins and using his discoveries to develop new immunotherapeutics. #AAHMSFellow @Monash_FMNHS
#proudPI. My Postdoc presented some exciting work within 3 mths of starting! Very exciting times. Congrats Narmadaa at being an AAS ECR Finalist @MonashVHI @MonashBDI
Denuja Karunakaran, PhD 👩🏽🔬🔬🧬🫀 retweeted
Fantastic talk on TRAIL by Dr Sian Cartland from @KavurmaMary’s group! There’s still so much we don’t know. Also, congratulations to Dr Cartland who’s a new Group Leader @HRIAust 👏🏽👏🏽👏🏽
PhD student Han Xu delivered a great flask talk on RIPK1 in macrophages and regulation of inflammation. @denujak
And it’s official! @atheroaussie annual scientific meeting has launched! A warm welcome by our current President @Judy_deHaan29! 50 years of celebrations has begun @atheroaussie
