#neurosurgeon and neuroscientist at the U of Minnesota working to translate #neuromodulation into therapies for #neurologic #pain and #psychiatric diseases
Minneapolis, MN
Joined November 2008
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David Darrow, MD retweeted
Join us TODAY at 4:00 PM ET for our latest webinar: "What’s the Latest? Advances in the Field of Neuromodulation" presented by Rushna Ali, MD, Nicholas Boulis, MD, David Darrow, MD, and Mike Staudt, MD.
The video will be available on our website and our YouTube channel.
Can we measure the “dose” of trigeminal balloon compression? In 41 TN patients, higher post-op serum NSE predicted less recurrence. pretty wild
@NeurosurgeryCNS @unicatt
doi:10.1227/neu.0000000000003724
Cingulotomy asks: not only “Does it hurt less?” but “Does pain control the person less?” At 8 years, 72% reported less pain, 55% stopped narcotics, and 67% improved family life. Historical data but is there a role? @NeurosurgeryCNS doi.org/10.1097/00006123-199…
Help us shape the future of neuromodulation for SCI. We're hiring a postdoc at Hennepin Healthcare/HHRI to work on epidural stimulation in chronic motor-complete SCI. Human SCI research experience is preferred.
Lab: restorativeneurotraumalab.or…
Apply: hhri.applicantpro.com/jobs/4…
Radar reflector localization for peripheral nerve surgery: 21/21 successful intraoperative localizations/retrievals, with no device-related complications. Clever adaptation for difficult anatomy.
@NeurosurgeryCNS
doi:10.1227/ons.0000000000002200
All 14 patients improved after cordotomy but 4 developed new contralateral pain. Pre-op temporal summation predicted who was at risk. A small, compelling case for physiologic phenotyping before irreversible pain surgery. @AssafBerger @NeurosurgeryCNS doi.org/10.1227/NEU.00000000…
Magown, Ko & Burchiel found that 32% of TN1 patients had no neurovascular compression. Yoshida et al now report asymmetric CSF flow and 78.6% BNI I/II after arachnoid dissection. Could “noncompressive” TN still be mechanical + vulnerable? @NeurosurgeryCNS doi.org/10.1227/neu.00000000…
The earlier paper that defined this clinical subgroup: “The Spectrum of Trigeminal Neuralgia Without Neurovascular Compression.” @OHSUBrain doi.org/10.1093/neuros/nyz04…
Some mail you never forget opening.
Thank you @NIH @NIH_NINDS + the HEAL Initiative for funding SENAP, a trial for central neuropathic pain: pain generated by the brain itself after stroke, MS, or spinal cord injury.
We finally know where it lives. Now we get to go there. 🧠
A privilege to build this with an amazing team @AlexHermanMDPhD (co-PI) and @TNetoff Michael Park Andrew Grande @DrDamienFair Ziad Nahas — psychiatry, engineering, neurosurgery, and neuroimaging on one problem.
Pain prevention after amputation may need to start when the nerve is cut. In 32 tumor amputations, RPNI was linked to less 12-week pain (25% vs 68.8%) and no phantom limb pain (0% vs 43.8%). Lin et al. @PKU1898 @NeurosurgeryCNS doi.org/10.1227/ons.00000000…
🤖 Made with AI
Negative SCS trials/explants were associated with higher 10-year mortality; ongoing SCS was not. Could a trial test pain diagnosis and responsiveness before later procedures...even fusion? Luikku et al. @nissen_mette @MFraunberg @NeurosurgeryCNS doi.org/10.1227/neu.00000000…
After the recent navigation paper, a classic from @NeurosurgeryCNS: in 1,216 TN patients, pain-free survival after a single RF rhizotomy was 57.7% at 5 years. The long tail of this curve is striking. doi.org/10.1097/00006123-200… #TrigeminalNeuralgia
David Darrow, MD retweeted
Join us next Wednesday at 4:00 PM as we continue the 2025 video series with “Neuroimaging for Trigeminal Neuralgia” presented by Kellen Mulford, PhD and Can Ozutemiz, MD
The video will premiere on the FPA’s YouTube Channel and on our website at: facepain.org/tag/webinars/
As a #NANS2027 Abstract Co-Chair, I hope you will submit work that expands how we think about the field: a new device, target, waveform, biomarker, mechanism, noninvasive therapy, unexpected result, patient-centered outcome, or better model of care.
Trainees/early-career investigators: don’t self-select out because your work feels early or hard to classify. If it is rigorous and taught us something, it belongs.
Due Aug 17, 1 PM CT. @NANS_ION
Details:
neuromodulation.org/abstract…
Submit:
abstractscorecard.com/cfp/su…
Accessing the foramen ovale can be the hardest part of TN rhizotomy. In 61 procedures, EM navigation cut fluoroscopy from 7.0 to 1.3 min, with no detected difference in pain outcomes. Great work @OmidShrk @rshervin @NeurosurgeryCNS doi.org/10.1227/ons.00000000…