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The entirety of science is built upon illegally downloaded scientific papers. I know this is true, because I read about it in an illegally downloaded paper. I made a step-by-step video guide to ensure that you don't accidentally download these papers:
youtu.be/heAOriNCEGQ
Myostatin Inhibitors (MI) remove the body's "brake pedal" on muscle growth. This is why a Belgian Blue cow has more muscle than you, despite never lifting a weight.
Now, grey-market labs are selling Apitegromab to biohackers for £18k/vial. I'll stick to the gym.
Sleep and diet have a huge impact on body composition.
I always drink protein shakes near gym time to suppress hunger.
And I use a mandibular advancement device (MAD) to eliminate obstructive sleep apnea and suppress hunger.
Genetic variants in Ezetimibe's target (NPC1L1) show an 82% reduction in all-cause dementia per 1 mmol/L lower non-HDL-C in a 2025 Mendelian randomization study.
Ezetimibe is generic ($6/month) so we would need a charitable rich person to fund a RCT.
alz-journals.onlinelibrary.w…
The way SI is going, in 10 years, getting a PhD will be like receiving an award for being the smartest caveman.
The FDA has approved the first continuous ketone monitor, the Libre Duo 10 Day.
It continuously tracks both glucose + BHB.
I've spoken a few companies in stealth and I think we are going to be continuously tracking a lot of things in the near future.
jamanetwork.com/journals/jam…
Regardless of the results of this study, I'm pretty bullish we will have multiple anti-aging compounds in the future.
I used to think time was an inelastic commodity, but maybe not ...
technologyreview.com/2026/10…
In a world of dating apps, looksmaxxing is here to stay.
The HHS needs to fund Clavicular to host MDs who will actually break down risk/reward ratios and say things like "Infertility is for chopped uncs and meth is not S-tier, fam."
Students pretend to do the homework.
Professors pretend to grade it.
It’s basically AI testing itself.
Idea: cap federal aid to the average tuition price of the inflation-adjusted cost of college tuition in 1971.
Then rebuild universities from first principles.
A couple years ago AI struggled with algebra.
It's now solving Millennium Prize Problems.
Commodity intelligence will trend towards $0 and frontier intelligence will tackle some of our hardest problems.
In the past, I was frustrated at expensive options for chemistry drawings.
ReShiki is a new desktop chemical editor that's free and open source.
I input the SMILES string for beta-carotene and exported to SVG and it worked well.
reshiki.com/
I was talking to an endocrinologist friend from the Russian part of the world and she told me they have degrees in biohacking/peptides.
I guess it makes sense considering a lot of peptides were researched there and are prescribed or OTC.
US reminder: you don’t need to talk to a doctor to get labs.
Pay cash at Goodlabs (CBC $4, CMP $5, lipids $8, T $15)
or donate blood and get a panel for $0.
goodlabs.com
Completely healthy children are heightmaxxing in Korea.
HGH prescriptions have exploded because parents don’t want their kids to get moggeed on the playground.
Looksmaxxing your child is one way to ensure your DNA is propagated.
pubmed.ncbi.nlm.nih.gov/4201…
Facebook became popular because only people with university emails could get access.
People go to the nightclub where there is a line.
Seems like great marketing.
Today we’re opening applications for the Life Sciences Verification Program.
Through the LSVP, life science professionals can use our models—including, for the first time, Mythos—with a new set of safeguards designed to enable the full range of biology-related work. We designed these new safeguards to provide a better experience for biologists and more protection from risk of misuse.
The program is launching in beta for teams of all kinds—from academic labs to startups, pharma companies, and more. We will continue to improve the program and expand access to individual Pro and Max plans over time.
Learn more about these access grants and apply: anthropic.com/news/life-scie…
Moderna/Merck’s personalized mRNA neoantigen vaccine (intismeran) is cool.
But have you heard about Coley’s toxins?
I learned we have been doing cancer immunotherapy for 130 years.
Unmarried men ↑
Alcohol ↓
Two hypothesis:
1) Marriage is a drinking problem
2) Sobriety is a dating problem





























