Dafil

💥 When "uncertain" becomes "causal" We called PPP1R9A a VUS — accurate for the evidence then. Now: CRISPR neurons grew larger dendrites but fired poorly. More structure, less function. That's what moves a variant. genomearc.com/blog-show/MzY6… #RareDisease #Genomics

Search Somatic variant AMP tiers, with global access for 27 tumor type : variant.genomearc.com/

A VUS with no second case stays a VUS. 🧬Search your variant free against Horizon's rare disease databases to find matching patients elsewhere. We have millions of currated variants to share. variant.genomearc.com/ #rarediseases #VUS #genome #diagnosis #genetics

Watch all Horizon case series: youtube.com/playlist?list=PL…

Struggling with tricky variants in rare neurodevelopmental disorders? We unpacked 3 real cases in Horizon Series: 🧬 TCF4 – broader phenotypes 🧬KCNH1 - G6PD focal epilepsy 🧬KMT2D – Kabuki syndrome Long-read genomics delivering answers. #raredisease #Genomics #VUS #Gene

Global Access, for everyone, predicting variant effect for rare disease (ACMG) and cancer (AMP). Type you germline or somatic variant for interpretation: variant.genomearc.com/ #raredisease #cancer #tumor #VUS #longread #genomics #genome #ACMG #AMP #somatic

NF1 deletion increases tumor risk. Horizon variant server returns multi-layer insights for geneticists: 🧬pathogenicity, 💊clinical trial drug insight, 🏥 three additional NF1 deletion samples Search your CNV/SV: variant.genomearc.com/ #NF1 #rarediseases #cancer #tumor #CNV

TF4 Gene variants and neurodevelopmental disorders. Part of GenomeArc's clinical genetics case series. 👉 Registration link in the comments. 📍 Watch (May 25, 2026) the case series on TCF4-related disorders:lnkd.in/gWfv97RB #raredisease #TCF4

Amazing! Since its launch one month ago, 50 genomic institutes are using Horizon ACMG/AMP variant classification server with free global access. Search your rare disease or tumor variant: variant.genomearc.com/ #raredisease #cancer #tumor #ACMG #AMP #variant #VUS

💡 This snapshot from the Horizon multimodal platform shows: -Germline ACMG Pathogenicity -Somatic AMP Tiers -Pharmacogenomic Insights -Case Insights Search your variant, free global access: variant.genomearc.com/

PTEN is a notorious pleiotropic gene; viewing both somatic and germline pathogenicity on a single page makes it easy to visualize disease associations across both cancer and rare diseases. Integrating ACMG and AMP for each variant. #cancer #somatic #rarediseases #PTEN

To resolve VUS variants, Horizon Variant Knowledgebase​ provides global open access to additional insights with identical variants. Search your VUS (SNV, Indel, SVs) to gain more insights: variant.genomearc.com/ #VUS #rarediseases #Genome #Gene

Search any variant to learn about their ACMG or AMP pathogenicity for #raredisease or #cancer This is free to use, and includes SNV, indels, and SVs, with non-coding annotations as well. Horizon variant search server: variant.genomearc.com/ #rarediseases #cancer #genome #VUS

Search your somatic variants to learn AMP Tier classification, drug insights and from additional tumors: -AMP Tier classification -FDA-approved drug insights -Additional supporting tumor data 🚀 Search Your Somatic Variant: lnkd.in/dDc-WtM3 #cancer #tumor #somatic