@crprindle

Lead Scientist and Peptide Designer at Endevica Bio. Formerly Nuckolls and Venkataraman labs @Columbia. she/her/hers.

 Chicago, IL
Joined March 2022
  • Tweets66
  • Following365
  • Followers355
7Media
Claudia Prindle retweeted
Kalohexis, LLC@kalohexisMay 29
We are pleased to announce a publication in @NatureComms demonstrating #melanocortin system activation as a promising target for next-generation #obesity treatment. Learn more: bit.ly/4nXeH6E
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Claudia Prindle retweeted
Dr. Jillian Seiler@jillyseilerJun 1
Proud to share our new paper from @kalohexis in @NatureComms! We've long known MC4R is critical for energy balance, but MC3R's role has been less clear. Our study shows that balanced MC3R/MC4R agonism unlocks biology not captured by MC4R alone. doi.org/10.1038/s41467-026-7…

Dual activation of MC3R and MC4R drives weight loss and reduces food intake in male primates with...

Nature Communications - Melanocortin receptor agonists are an alternative to GLP-1s for weight loss. The study showed that activating MC3R & MC4R together demonstrated strong weight loss,...

nature.com
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Excited to share this new publication from Endevica Bio!
Frontiers - Endocrinology@FrontEndocrinolMar 12
New Research: The melanocortin receptors as targets for general obesity: contextualizing clinical failures and analyzing future perspectives frontiersin.org/articles/10.… #FrontiersIn #Endocrinology
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New Research: The melanocortin receptors as targets for general obesity: contextualizing clinical failures and analyzing future perspectives frontiersin.org/articles/10.… #FrontiersIn #Endocrinology
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Excited to share this new preprint from Endevica Bio!
bioRxiv Neuroscience@biorxiv_neursci29 Nov 2025
Dual Activation of MC3R and MC4R Drives Weight Loss and Reduces Food Intake in Obese Primates biorxiv.org/content/10.1101/… #biorxiv_neursci

Dual Activation of MC3R and MC4R Drives Weight Loss and Reduces Food Intake in Obese Primates

The melanocortin system plays a central role in regulating hunger and satiety, making it an attractive target for treating metabolic disease. However, the limited clinical success of selective...

biorxiv.org
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Dual Activation of MC3R and MC4R Drives Weight Loss and Reduces Food Intake in Obese Primates biorxiv.org/content/10.1101/… #biorxiv_neursci

Dual Activation of MC3R and MC4R Drives Weight Loss and Reduces Food Intake in Obese Primates

The melanocortin system plays a central role in regulating hunger and satiety, making it an attractive target for treating metabolic disease. However, the limited clinical success of selective...

biorxiv.org
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Had a great time attending #BIO2025 with the amazing Endevica team!
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If you have the time, check out the Formation of Metallocene Single-Molecule Junctions Via Metal–Metal Bonds | Nano Letters. One of the final works to come out of my PhD working with the dream team (@friendlee525 , @wanzhuoshi, and Shayan)! pubs.acs.org/doi/10.1021/acs…

Formation of Metallocene Single-Molecule Junctions Via Metal–Metal Bonds

Abstract. We study single-molecule junction formation of group VIII metallocenesferrocene, ruthenocene, and osmocenewith gold (Au)

pubs.acs.org
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Claudia Prindle retweeted
Woojung Lee@friendlee52515 Feb 2025
Our work on single-molecule devices with metal-metal bonds is out in @NanoLetters @ACSPublications! Thanks for the collaboration and support @crprindle @wanzhuoshi Shayan, Michael, Latha! Check out our paper: pubs.acs.org/doi/10.1021/acs…

Formation of Metallocene Single-Molecule Junctions Via Metal–Metal Bonds

Abstract. We study single-molecule junction formation of group VIII metallocenesferrocene, ruthenocene, and osmocenewith gold (Au)

pubs.acs.org
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157 years of science, 27 years of being an inspiration to a first-gen Polish-American chemist. Happy Birthday to Dr. Marie Skłodowska Curie!
Science Magazine
@ScienceMagazine7 Nov 2023
Happy 156th Birthday, Marie Skłodowska Curie! She was the first woman to receive a #NobelPrize and the first person to receive the honor twice. In 2017, @SciMagBooks toured the dynamics that established her as "the most iconic of all female scientists." scim.ag/4Jv

The making and remaking of Marie Curie

The famous physicist's legacy looms large 150 years after her birth

science.org
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Claudia Prindle retweeted
The Nobel Prize
@NobelPrize7 Nov 2024
Happy birthday to Marie Skłodowska Curie, who was born on this day in 1867. Marie Curie was the first person to be awarded the Nobel Prize twice, and is still the only individual to receive the prize in two different science categories. Find out more: bit.ly/2EQeIam
Black and white portrait of Marie Skłodowska Curie.

ALT Black and white portrait of Marie Skłodowska Curie.

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Claudia Prindle retweeted
Endpoints News
@endpts18 Oct 2024
David Baker has been pushing the limits of designing proteins for decades. endpts.com/nobel-winner-davi…

A conversation with Nobel Prize winner David Baker on the future of AI in protein design — and...

David Baker has been pushing the limits of designing proteins for decades. The computational biologist started developing software, called Rosetta, to study and design proteins in the 1990s. He’s now...

endpoints.news
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Claudia Prindle retweeted
The Nobel Prize
@NobelPrize9 Oct 2024
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
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Claudia Prindle retweeted
J. Am. Chem. Soc.@J_A_C_S12 Mar 2024
Spotlights on Recent JACS Publications | Journal of the American Chemical Society #JACSSpotlights pubs.acs.org/doi/10.1021/jac…

Spotlights on Recent JACS Publications

With electric vehicles and hybrids now comprising 16% of yearly light-duty vehicle sales in the United States, car manufacturers like Tesla are developing

pubs.acs.org
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I got an awesome birthday present from @J_A_C_S - our work was given a spotlight! Come learn about how we’re making steps toward nanoscale electronics: pubs.acs.org/doi/10.1021/jac… @wanzhuoshi @LiangLi9510

Spotlights on Recent JACS Publications

With electric vehicles and hybrids now comprising 16% of yearly light-duty vehicle sales in the United States, car manufacturers like Tesla are developing

pubs.acs.org
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Claudia Prindle retweeted
Woojung Lee@friendlee52516 Feb 2024
Our latest #research on the ferrocene-based single-molecule electronics has been published with @SpringerNature in @NatureComms ! Thanks for the collaboration and support @LiangLi9510 @mikeinkpen @ChemColumbia ! See article in: doi.org/10.1038/s41467-024-4…
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What did I get for Valentine’s Day? Our article online in the Journal of Chemical Education! Read how @norchanian and I use TikTok as a science communication tool, reaching millions of students across the globe. Send to your sweetie! pubs.acs.org/doi/10.1021/acs…

Short-Form Videos as an Emerging Social Media Tool for STEM Edutainment

Abstract. As social media platforms continue to grow in popularity, there is an increasing need for science outreach teams to bring STEM content to the vir

pubs.acs.org
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Claudia Prindle retweeted
J. Am. Chem. Soc.@J_A_C_S3 Feb 2024
Effective Gating in Single-Molecule Junctions through Fano Resonances | Journal of the American Chemical Society @Colulmbia @ChemColumbia #Gating #SingleMOlecule #Junctions #Fano #Resonances pubs.acs.org/doi/10.1021/jac…
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I’m so excited that our paper is finally online at @J_A_C_S! A huge shoutout to our amazing collaborators @BoWLaursen and @jesperdj10 at @UCPHnanoscience. This team has been awesome to work with - cheers and skål!
Liang Li@LiangLi951031 Jan 2024
Wanna know how to boost molecular conductance through Fano resonance? Check out our recent @J_A_C_S paper with the leading authors @crprindle and @wanzhuoshi, under the supervision of Colin and Latha. pubs.acs.org/doi/abs/10.1021…
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Claudia Prindle retweeted
J. Am. Chem. Soc.@J_A_C_S10 Aug 2023
Radical Single-Molecule Junctions | Journal of the American Chemical Society @LiangLi9510 @crprindle @wanzhuoshi @Columbia @ChemColumbia #Radical #SingleMolecule #Junctions #JACSPerspective pubs.acs.org/doi/10.1021/jac…

Radical Single-Molecule Junctions

Abstract. Radicals are unique molecular systems for applications in electronic devices due to their open-shell electronic structures. Radicals can function

pubs.acs.org
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