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Pleased that the 2nd part of my PhD in now available as a preprint! Here, we investigated the epigenomic and transcriptomic changes occurring upon PRC2 depletion in AML cells. biorxiv.org/content/10.1101/…. A thread🧵1/17
Thanks to my supervisors for guiding this work @jbond2019 @colmr and to everyone involved for all the important and hard work put in @iamnotaprawn @TheodoraGrosu @ClaireFitzG18 Noura Maziak, Rebecca Ling, @andiroy, @vaquerizasjm. 16/17
Finally, thanks to @Researchirel @GenomicsCRT @MSCActions for funding this work! And thanks to @ucddublin @UCDMedicine @sysbioire for the support offered. 17/17
Cosmin Tudose retweeted
New data from our group!
Working with Kholodenko/Rukhlenko groups @sysbioire we used structure-based modelling to find novel non-expected AML drug combos, which we validated in vivo. Huge thanks to @IrishCancerSoc for funding Luke Jones @iamnotaprawn biorxiv.org/content/10.1101/…
Many thanks to my supervisors @jbond2019 and @colmr, to everyone in @sysbioire and to the @GenomicsCRT! :)
Congratulations to Cosmin Tudose on passing his viva yesterday! 🥂🎉
Cosmin is co-supervised by @colmr & @jbond2019 funded by @GenomicsCRT. Thesis title: "Defining molecular vulnerabilities in childhood leukaemia through biological network analysis".
Well done @cosmint_! #viva
Cosmin Tudose retweeted
Congrats to Gold Medal Runner Up @cosmint_ 👏 🎉 His study shows that Gene expression is a better predictor of cancer cell sensitivity to treatments than gene regulatory networks. 🔍 #conwayfest24 #CancerResearch #Genomics #CRISPR





