MD | Building something new in Bio | ai science / acc | now @shipfr8 | prev LBF, Harvard, the residency, Telos Circle

Boston, MA
Joined December 2021
Constantin retweeted
Pop-Corn: Predicting Perturbation Phenotype Effects Across Single-Cell and Spatial Contexts biorxiv.org/content/10.64898…
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The hardest part of building data centres in the US right now is finding enough electricians, plumbers and welders. Germany has trained these at scale for decades through its apprenticeship system. Underrated European advantage, if we ever decide to build.
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Complete List of Mind Uploading Literature Thanks to the people who helped me yesterday find a few missing works on mind uploading. As promised, here's the complete list of mind uploading works I found, ordered chronologically. Please let me know if I missed anything! 1929 Bernal: The World, the Flesh and the Devil: An Enquiry into the Future of the Three Enemies of the Rational Soul 1955 Pohl: The Tunnel Under the World 1971 Fredericksen: I Have a Pipedream... And You’d Better Believe It! (second instalment), with Backtalk from Readers 1978 Dennett: Where Am I? 1979 Dyson: Time without end: Physics and biology in an open universe 1979 Moravec: Today’s Computers, Intelligent Machines and Our Future 1980 Searle: Minds, Brains, and Programs 1980 Pylyshyn: The “Causal Power” of Machines 1981 Hofstadter & Dennett: The Mind’s I: Fantasies and Reflections on Self and Soul 1981 Vinge: True Names 1982 Rucker: Software 1982 Savitt: Searle’s Demon and the Brain Simulator 1984 Parfit: Reasons and Persons 1985 Cuda: Against Neural Chauvinism 1986 talk/1987 print Moravec: Dualism through Reductionism 1988 Moravec: Mind Children: The Future of Robot and Human Intelligence 1989 Merkle: Large Scale Analysis of Neural Structures 1990 Donaldson: Metamorphosis: An Alternative to Uploading 1992 Moravec: Pigs in Cyberspace 1993 Merkle: Uploading: Transferring Consciousness from Brain to Computer [2013: Uploading] 1994 Tipler: The Physics of Immortality: Modern Cosmology, God and the Resurrection of the Dead 1994 Egan: Permutation City 1994 archived Strout: Uploading by the Moravec Procedure 1994 Merkle: The Molecular Repair of the Brain 1994 Hanson: If Uploads Come First: The Crack of a Future Dawn 1995 Chalmers: Absent Qualia, Fading Qualia, Dancing Qualia 1995 Leitl: Neurosuspension and Uploading by 1995; 2006 version Strout: Mind Uploading Home Page 1996? Malickas: Gradual Uploading as a Cognition of Mind 1996 archived Strout: Get Involved [Mind Uploading Research Group] 1996 Freitas Jr.: The Future of Computers 1998 van Heuveln et al.: Let's Dance! The Equivocation in Chalmers' Dancing Qualia Argument 1999 Moravec: Robot: Mere Machine to Transcendent Mind 1999 Hayles: How We Became Posthuman: Virtual Bodies in Cybernetics, Literature, and Informatics 1999 Kurzweil: The Age of Spiritual Machines: When Computers Exceed Human Intelligence 2000 archived Sandberg: Uploading [Aleph archive/index] 2000 Bell & Gray: Digital Immortality [related article: 2001] 2002 Goertzel: Liberating Minds from Brains 2002 Hayworth: Single Brain Physical Slice Library Proposal: Creating a Complete Human Neural Connectivity Database via Sparse, Automatically-Directed Ultramicroscopic Imaging Using an Automated Retrieval Brain Slice Storage System 2003 Bostrom: Ethical Issues in Advanced Artificial Intelligence 2004/2005 McCabe: Universe creation on a computer 2004 Piccinini: Functionalism, computationalism, and mental states 2004 Hanson: The Next Really Big Enormous Thing 2005 Dix: The Brain and the Web: A Quick Backup in Case of Accidents 2005 Kurzweil: The Singularity Is Near: When Humans Transcend Biology 2007 Astakhov: Continuum of consciousness: Mind uploading and resurrection of human consciousness. Is there a place for physics, neuroscience and computers? 2008 Sandberg & Bostrom: Whole Brain Emulation: A Roadmap 2008 Hanson: Economics of the Singularity 2008 Hanson: The Economics of Brain Emulations 2008 Astakhov: Mind Uploading and Resurrection of Human Consciousness. Place for Science? 2010 Chalmers: The Singularity: A Philosophical Analysis [2014: Uploading: A Philosophical Analysis] 2010 Piccinini: The Mind as Neural Software? Understanding Functionalism, Computationalism, and Computational Functionalism 2010 Branwen: How Complex Are Individual Differences? 2010 Hayworth: Killed by Bad Philosophy: Why Brain Preservation Followed by Mind Uploading Is a Cure for Death 2011 Shores: Misbehaving Machines: The Emulated Brains of Transhumanist Dreams 2011 Piccinini & Craver: Integrating psychology and neuroscience: Functional analyses as mechanism sketches 2011 Walker: Personal Identity and Uploading [2014: Uploading and Personal Identity] 2011 Levy: Searle’s Wager 2011 Agar: Ray Kurzweil and Uploading: Just Say No! 2012 Sandberg: How many persons can there be: brain reconstruction and big numbers 2012 Goertzel: When Should Two Minds Be Considered Versions of One Another? 2012/2013 Barrett: Multiple Realizability, Identity Theory, and the Gradual Reorganization Principle 2012 site; 2015 version Dalrymple: NemaLoad 2012 Chalmers: The Singularity: A Reply to Commentators 2012 Deca: Available Tools for Whole Brain Emulation 2012 Corabi & Schneider: The Metaphysics of Uploading [2014: If You Upload, Will You Survive?] 2012 Sotala & Valpola: Coalescing Minds: Brain Uploading-Related Group Mind Scenarios 2012 Rothblatt: The Terasem Mind Uploading Experiment 2012 Heidari: Brain, Time, Consciousness and Mind Uploading 2012 Koene: Embracing Competitive Balance: The Case for Substrate-Independent Minds and Whole Brain Emulation 2012 Koene: Experimental Research in Whole Brain Emulation: The Need for Innovative in Vivo Measurement Techniques 2012 Koene: Fundamentals of Whole Brain Emulation: State, Transition and Update Representations by 2012 Koene: The History of SIM, Whole Brain Emulation and Mind Uploading 2012 Bamford: A Framework for Approaches to Transfer of a Mind’s Substrate 2012 Choe et al.: Time, Consciousness, and Mind Uploading 2013 Sandberg: Feasibility of Whole Brain Emulation 2013 Eth et al.: The Prospects of Whole Brain Emulation within the next Half-Century 2013 Alstott: Will We Hit a Wall? Forecasting Bottlenecks to Whole Brain Emulation Development 2013 Eckersley & Sandberg: Is Brain Emulation Dangerous? 2013 Koene: Uploading to Substrate-Independent Minds 2013 Koene & Deca: Editorial: Whole Brain Emulation seeks to Implement a Mind and its General Intelligence through System Identification 2013 Geraci: Mind Uploading 2013 Bainbridge: Personality Capture and Emulation 2014 Sandberg: Being Nice to Software Animals and Babies 2014 Sandberg: Ethics of brain emulations 2014 Sandberg: Monte Carlo Model of Brain Emulation Development 2014 Szigeti et al.: OpenWorm: an open-science approach to modeling Caenorhabditis elegans 2014 Strout: Practical Implications of Mind Uploading 2014 Goonan: The Future of Identity: Implications, Challenges, and Complications of Human/Machine Consciousness 2014 Wiley: A Taxonomy and Metaphysics of Mind-Uploading 2014 Muehlhauser: Randal Koene on whole brain emulation 2014 Rothblatt: Virtually Human: The Promise and the Peril of Digital Immortality 2014 Pigliucci: Mind Uploading: A Philosophical Counter‐Analysis 2014 More: The Enhanced Carnality of Post-Biological Life 2014/2015 Cerullo: Uploading and Branching Identity 2014 Wellington: Whole Brain Emulation: Invasive vs. Non‐Invasive Methods 2014 Vita-More: Design of Life Expansion and the Human Mind 2014 Agar: On the Prudential Irrationality of Mind Uploading 2014 N. Olson: The Values and Directions of Uploaded Minds 2014 Koene: Feasible Mind Uploading 2014 Loosemore: Qualia Surfing 2014 Hanson: What Will It Be Like To Be an Emulation? 2014 Blackford & Broderick: Intelligence Unbound: The Future of Uploaded and Machine Minds 2014/2021 edition Horie & Kaneko: Imitated Mind Uploading by Using Electroencephalography 2014 Aaronson: Could a Quantum Computer Have Subjective Experience? 2015 Mercer: Whole Brain Emulation Requires Enhanced Theology, and a “Handmaiden” 2015/2016/2018 Wiley & Koene: The Fallacy of Favouring Gradual Replacement Mind Uploading Over Scan-and-Copy 2015/2016 Hayworth: Mind Uploading: An Argument for the Scientific and Technical Plausibility of Preserving Thoughts Indefinitely 2015 Shanahan: Whole Brain Emulation 2016 Sandberg: Energetics of the brain and AI 2016 Sotiropoulou et al.: Medical image processing using brain emulation 2016 Linssen & Lemmens: Embodiment in Whole-Brain Emulation and its Implications for Death Anxiety 2016 Cerullo: The Ethics of Exponential Life Extension through Brain Preservation 2016 Kassan: Uploading Your Mind Does Not Compute 2016 Kuhn: Virtual Immortality: Why the Mind-Body Problem Is Still a Problem 2016 Hanson: The Age of Em: Work, Love, and Life when Robots Rule the Earth 2017 Panin: Philosophy of Mind Uploading. Subjectivism vs. Objectivism 2017 Mercer: A Theological Assessment of Whole Brain Emulation: On the Path to Superintelligence 2017 E. T. Olson: The Central Dogma of Transhumanism 2017 Japanese/2022 English Watanabe: 脳の意識 機械の意識: 脳神経科学の挑戦 [Brain Consciousness, Machine Consciousness] / From Biological to Artificial Consciousness: Neuroscientific Insights and Progress 2017/2023 Johnson: Against functionalism: why I think the Foundational Research Institute should rethink its approach 2017 Serruya: Connecting the Brain to Itself through an Emulation 2017 Häggström: Aspects of Mind Uploading 2018 Sarma et al.: OpenWorm: overview and recent advances in integrative biological simulation of Caenorhabditis elegans 2018 Laakasuo et al.: What makes people approve or condemn mind upload technology? Untangling the effects of sexual disgust, purity and science fiction familiarity 2018/2019 Getsemi: New research shall be initiated in regard with the effects of mood alternation during neurological shutdown 2019 E. T. Olson: The Metaphysics of Artificial Intelligence 2019 Stiefel & Brooks: Why is There No Successful Whole Brain Simulation (Yet)? 2019 Gaitán: Heaven on Earth: The Mind Uploading Project as Secular Eschatology 2019 Collins: The case for emulating insect brains using anatomical “wiring diagrams” equipped with biophysical models of neuronal activity 2019 de Brito Fernandes: From Birth to the Grave in the New Age: The Challenges of Whole Brain Emulation in the Portuguese Legal Concepts of Personhood and Death 2019 Yampolskiy: Personal Universes: A Solution to the Multi-Agent Value Alignment Problem 2019 Schneider: Artificial You: AI and the Future of Your Mind 2019 Lorrimar: Mind Uploading and Embodied Cognition: A Theological Response 2019 Huang et al.: A Single-Cell Level and Connectome-Derived Computational Model of the Drosophila Brain 2020 Bandyopadhyay: Uploading Consciousness: The Evolution of Conscious Machines of the Future 2020/2021 Shulman & Bostrom: Sharing the World with Digital Minds 2020 Piccinini: Neurocognitive Mechanisms: Explaining Biological Cognition 2020 Carlsmith: How much computational power does it take to match the human brain? 2020 Szpyt: Copyright Challenges Concerning the Development of Mind Uploading 2020/2021 Laakasuo et al.: The dark path to eternal life: Machiavellianism predicts approval of mind upload technology 2020 Ostiz Blanco: ¿Es realmente accesorio el cuerpo? Cuestiones por resolver acerca del mind uploading 2020/2021 Häggström: Aspects of Mind Uploading 2020 Cave: AI: Artificial Immortality and Narratives of Mind Uploading 2021 Leis: Immortality Through Mind Uploading and Resurrection 2021/2022 Maimon & Hemmo: Does Neuroplasticity Support the Hypothesis of Multiple Realizability? 2021 Zlatović: Until Death Do Us Part and They Upload Us Into Clones: An Analysis of Film Narratives About Mind Uploading and the Myth of Immortality 2021 Mercer & Trothen: Mind Uploading: Cyber Beings and Digital Immortality 2021 Mercer & Trothen: Religion and the Technological Future: An Introduction to Biohacking, Artificial Intelligence, and Transhumanism 2021 D. Wang et al.: Mapping the BCPNN Learning Rule to a Memristor Model 2021 Eichener & Peuckmann: Mind uploading als Seele 4.0? Trauerkultur in Zeiten der Digitalisierung 2021 Piccinini: The Myth of Mind Uploading 2021 Liu et al.: A Tantalum Disulfide Charge-Density-Wave Stochastic Artificial Neuron for Emulating Neural Statistical Properties 2021 Goldwater: Uploads, Faxes, and You: Can Personal Identity Be Transmitted? 2021 Scheffer & Meinertzhagen: A connectome is not enough: what is still needed to understand the brain of Drosophila? 2021 Conway: Faculty Opinions recommendation of The dark path to eternal life: machiavellianism predicts approval of mind upload technology 2021 Warby: A Critical Enquiry into the Metaphysics for Mind Uploading 2021 Clowes & Gärtner: Slow Continuous Mind Uploading 2021 Schmitz: TechnoBrainBodies-in-Cultures: An Intersectional Case 2021 Sorgner: Transhumanism Without Mind Uploading and Immortality 2022 McKenzie: The brain is all you need 2022 Puzio: Über-Menschen. Philosophische Auseinandersetzung mit der Anthropologie des Transhumanismus 2022 Chomanski: Sims and Vulnerability: On the Ethics of Creating Emulated Minds 2022 Gankhuu: Ethics of Mind Uploading: Personal Identity 2022 Mandelbaum: Everything and More: The Prospects of Whole Brain Emulation 2022 E. T. Olson: The Metaphysics of Transhumanism 2022 Gasser: Personale Identität, Verkörperung und Personentransfers: Eine identitätstheoretische Skizze 2022 Gasser: Transfer meines Ichs? Identitätstheoretische Überlegungen zu Mind Uploading und digitaler Existenz 2022 Landgrebe & Smith: Unsterblichkeit 2.0 2022 Higuchi et al.: High performance, large-scale multi-compartment Hodgkin-Huxley simulation of Drosophila’s whole-brain neural circuit model 2022 Sikau: Rehearsing Posthumanism 2022 Jansen: Ich und mein digitales Selbst 2022 Jansen & Klein: Seele digital: Ewiges Leben im Computer? 2022 Jansen & Klein: Seele digital: Mind Uploading, virtuelles Bewusstsein und Auferstehungshoffnung 2022 Knaup: Mind Uploading? Eine philosophische Kritik 2022 Mühling: Das iKalb, Relationalität und der ausgedehnte Leib: Theologische Perspektiven auf Post- und Transhumanismus 2022/2023 Laakasuo et al.: Would you exchange your soul for immortality? – Existential meaning and afterlife beliefs predict mind upload approval 2022 Becker: Von der ewigen Seele zum unendlichen Geist: Jenseitsverlust und technischer Fortschritt 2022/2023?; 2026 revision Liaqat: South Asian Transhumanist Posthuman Ontologies: The Relationship between Vehicle Art and Mind Uploading in Uzma Aslam Khan’s Trespassing [2026: Vehicle Art and Mind Uploading: Transhumanist Posthuman Ontologies in Uzma Aslam Khan’s Trespassing] 2022 Klein: Digitale Neugeburt als ein Anderer? Vom Geist-Körper-Dualismus zum Subjekt als Kulturprodukt 2022 Grinschgl et al.: Human enhancement and personality: A new approach towards investigating their relationship 2022 Rathi: Approaches to Artificial General Intelligence: An Analysis 2022 Ингельдеев & Яковлева: Elena Rykova's “101% mind uploading”: On the Materialism, Theatre and Sonic Resonance 2023/2024 Diéguez & García-Barranquero: The Singularity, Superintelligent Machines, and Mind Uploading: The Technological Future? 2023 Weber: Could you move from your biological body to a computer? An expert explains ‘mind uploading’ 2023 Lyreskog et al.: Merging Minds: The Conceptual and Ethical Impacts of Emerging Technologies for Collective Minds 2023 Haspel et al.: The time is ripe to reverse engineer an entire nervous system: simulating behavior from neural interactions 2023 Branwen: Modular Brain AUNNs for Uploads 2023 Liu et al.: Artificial Neuronal Devices Based on Emerging Materials: Neuronal Dynamics and Applications 2023 Pauketat et al.: Public Opinion on AI Safety: AIMS 2023 Supplement 2023 Wissinger & E. B. Wang: Mind Uploading in Artificial Intelligence 2023 Wiley: Nondestructive Mind Uploading and the Stream of Consciousness 2023; 2022 issue Sikau: Rehearsing Upload 2023 Collins: Feasibility of Mapping the Human Brain with Expansion X-Ray Microscopy 2023 Echarte Alonso: Exploring moral perception and mind uploading in Kazuo Ishiguro's ‘Klara and the Sun': ethical-aesthetic perspectives on identity attribution in artificial intelligence 2023 Watanabe: AI consciousness and neuroscientifically plausible “seamless” mind-uploading 2023 Rouleau & Levin: The Multiple Realizability of Sentience in Living Systems and Beyond 2023 Henke: Puzio, Anna: Über-Menschen. Philosophische Auseinandersetzung mit der Anthropologie des Transhumanismus. / Jansen, Ludger, und Rebekka A. Klein (Hrsg.): Seele digital. Mind Uploading, virtuelles Bewusstsein und Auferstehungshoffnung 2023 R. Krzanowski & J. Krzanowski: Does whole brain emulation entail the emulation of mental disorders? 2023 Gäb: Should You Upload Your Mind? 2023 Raimondi: Mind Uploading 2023/2024 Alter et al.: Mind Uploading 2024 Rosenthal: Whole Brain Emulation 2024 Brenner: Personal Ontology and Life after Death, Part 2: Mind Uploading 2024 Thornton et al.: Our Futures in Mind Uploading: Public Perceptions and Narratives 2024/2025/2026 Seth: Conscious artificial intelligence and biological naturalism 2024/2025 Zeleznikow-Johnston et al.: What are memories made of? A survey of neuroscientists on the structural basis of long-term memory 2024 E. J. P. Fisher & E. Fisher: Fresh thinking about Neo-genetic and Social Perspectives of Mind Upload capabilities beyond the Biological Human Body 2024/2025 Findlay et al.: Dissociating Artificial Intelligence from Artificial Consciousness 2024 Kleiner: Consciousness qua Mortal Computation 2024 Kleiner & Ludwig: The case for neurons: a no-go theorem for consciousness on a chip 2024 Igarashi: Future projections for mammalian whole-brain simulations based on technological trends in related fields 2024 L. Li et al.: Oxygen vacancies modulated VO2 for neurons and Spiking Neural Network construction 2024 Inbaraj & Ravikumar: Encountering Disability through Mind Uploading: A Transhumanist Reading of Richard A. Morgan's Altered Carbon 2024 Breul: Seele digital. Mind Uploading, virtuelles Bewusstsein und Auferstehungshoffnung, hg. v. Ludger Jansen / Rebekka A. Klein 2024 Zhao et al.: An integrative data-driven model simulating C. elegans brain, body and environment interactions 2024/2026 Johnson: A Paradigm for AI Consciousness 2024 Alexandre e Castro: What Neurohacking Can Tell Us About the Mind: Cybercrime, Mind Upload and the Artificial Extended Mind 2024/2025 Lin et al.: Achieving neuronal dynamics with spike encoding and spatial-temporal summation in vanadium-based threshold switching memristor for asynchronous signal integration 2024 Shiu et al.: A Drosophila computational brain model reveals sensorimotor processing 2024 Weir: The Personal Identity Dilemma for Transhumanism 2024 Kumar et al.: Merging biological and artificial consciousness: A neuroscience perspective of whole brain emulation 2024 Miziev et al.: Comparative analysis of energy transfer mechanisms for neural implants 2024 Magerstädt: Upload, Cyber-Spirituality and the Quest for Immortality in Contemporary Science-Fiction Film and Television 2024 Bohrmann: Ludger Jansen/Rebekka A. Klein (Hg.): Seele digital. Mind uploading, virtuelles Bewusstsein und Auferstehungshoffnung 2024 Smetana: Mind Uploading: Philosophical Horizons of Digital Existence 2024 Lu et al.: Simulation and assimilation of the digital human brain 2024 Zhan: I am no abstract object: a novel challenge to mind uploading 2025 Ali: The Unified Quantum-Consciousness Framework Integrating EQST-GP Physics with Veronica X Pro Architecture for Conscious AI 2025/2026 German et al.: Functional recovery of the adult murine hippocampus after cryopreservation by vitrification [2025: Functional recovery of adult brain tissue arrested in time during cryopreservation by vitrification] 2025 McKenzie et al.: Practitioner forecasts of technological progress in biostasis 2025 Žalec: The Plausibility of Mind Uploading 2025/2026 Milinkovic & Aru: On biological and artificial consciousness: A case for biological computationalism 2025 Kaunda & Lee: ‘Through Valley of the Shadow of Death’: Death In-Between and Betwixt “Life After Life” in Mind Uploading Immortality 2025 Linssen & Koene: Functional Tests Guide Complex “Fidelity” Tradeoffs in Whole-Brain Emulation 2025 Weber: Selective Optimism about Mind-Uploading 2025 Weber: The multiplicity objection against uploading optimism 2025 Burger et al.: Death is an Engineering Challenge 2025/2026 Kleiner: Defining biological naturalism 2025 Vallverdú & Rius: NeuroQ: Quantum-Inspired Brain Emulation [correction: 2025] 2025 Sato & Ota: Is it Rational to Choose Mind-uploading?: An Overview of Recent Philosophical Discussions 2025 Watanabe: Creating Conscious Machines: The Missed Nobel Prize of Shun’ichi Amari and Future Challenges 2025 Johnson: [Computational introspection, qualia self-report and substrate transfer] 2025 Wójcik: Fenomenalna natura świadomości jako granica uploadowania umysłu w świetle neurokognitywistyki 2025 Pasupuleti: AI-Enhanced Neuroengineering: Brain Uploading, Memory Transfer, and the Future of Consciousness 2025/2026 Block: Can only meat machines be conscious? 2025 Zanichelli et al.: State of Brain Emulation Report 2025 2025 Koene: From Structure to Self: Philosophy of Mind as the Key to Brain Emulation 2025 Runge: The ontological and moral status of whole brain emulations in neo-Aristotelian naturalism 2025 Kuriyama et al.: Microscopic-Level Mouse Whole Cortex Simulation Composed of 9 Million Biophysical Neurons and 26 Billion Synapses on the Supercomputer Fugaku 2025 Gal-Or: LKM Collective, Mind Uploading & Cloud AI 2025 Pawlak & Howard: Neuromorphic algorithms for brain implants: a review 2025 Xie: A multiscale brain emulation-based artificial intelligence framework for dynamic environments 2025 Xia & J. Li: Mind uploading and its metaphysical foundations: from role functionalism to realizer functionalism 2026 Lerchner: The Abstraction Fallacy: Why AI Can Simulate But Not Instantiate Consciousness 2026 Godbole: Personal Identity and Mind Uploading: A Cartesian Analysis 2026 Percy: Can analogue minds live forever? Introducing the ‘Step-Structure Principle’ as a testable limit on the Church Turing thesis for brain emulation 2026/2027; release unconfirmed Percy: Machine Consciousness and Mind Uploading 2026 Comerci: If the code hurts: on pain and virtual brains 2026 Fahy et al.: Ultrastructural and Histological Cryopreservation of Mammalian Brains by Vitrification 2026 Piccinini: The neurobiophysical substrate of consciousness 2026 H. Wang: Mind Uploading from the Perspective of Mortal Computation 2026 Pearson: Consensual Mind-Cloning by Sparse Self-Capture 2026 Freeman: From Worm to Human: Scaling Brain Emulation 2026 Reser: Why Whole-Brain Emulation Must Reproduce Iterative Mental Continuity 2026 Brinz: From simulating to duplicating the brain 2026 Pryor: Can (and should) consciousness be uploaded to a machine? 2026 Mishra: The Dimensionality Gap: Three Scaling Barriers to AGI on Von Neumann Architectures, and a Path Forward Through Neuromorphic-Photonic Substrates 2026 Dravid: Gradual Neural Integration: A Path to Consciousness Continuity and Potential Immortality 2026 Johnson: Compilable Wishes 2026 Bennett: A Mind Cannot Be Smeared Across Time 2026 Bennett: Spacetime Bounds on Consciousness 2026 Gao: Asymmetrical replacement and the limits of functionalism: a reverse thought experiment 2026 Kanai & Ma: Canonical Functionalism: Defining Functional Structure without Observer-Relative Semantic Maps 2026 Kanai & Ma: Intrinsic Computational Functionalism and Simulated Consciousness 2026 Raime & Misron: Beyond Human Potential: Integrating Mind Uploading and AI for Enhanced Productivity in Malaysia's Workforce 2026 Ma & Kanai: Intrinsic Computational Functionalism: From Observer-Relative Maps to Observer-Independent Structures 2026 Saranga: Whole Brain Emulation (WBE): Engineering the Mind, Breaking the Bottlenecks, and Not Accidentally Inventing Digital Slavery 2026 Y. Wang: Colleague Skill: an attempt at distillation and mind uploading
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Daniel is brillant, if you’re interested in mind uploading, partial brain replacement, synconetics, brain in a jar tech or philosophy, he’s the person.
Help Needed: Missing Mind Uploading Works I'm trying to build as comprehensive a collection of mind uploading literature as I can: papers, books, chapters, essays, blog posts, and (if necessary) relevant fiction. I've found most of what is on my list, but I'm still looking for the works below. Can anyone point me towards open-access versions, author manuscripts, library holdings or other legitimate sources? If you're an author or have a copy you're permitted to share, I'd love to hear from you. PDFs are ideal, including readable scans I can OCR, but EPUBs and other formats are welcome too! I'm missing 30 works, and I have only partial copies of seven, marked with an asterisk (*) BOOKS & EDITED COLLECTIONS: – Hofstadter & Dennett (1981), The Mind’s I: Fantasies and Reflections on Self and Soul* – Jansen & Klein, eds. (2022), Seele digital: Mind Uploading, virtuelles Bewusstsein und Auferstehungshoffnung* JOURNAL PAPERS & COMMENTARIES: – Astakhov (2008), Mind Uploading and Resurrection of Human Consciousness. Place for Science? – Heidari (2012), Brain, Time, Consciousness and Mind Uploading – Zlatović (2021), Until Death Do Us Part and They Upload Us Into Clones: An Analysis of Film Narratives About Mind Uploading and the Myth of Immortality – Eichener & Peuckmann (2021), Mind uploading als Seele 4.0? Trauerkultur in Zeiten der Digitalisierung – Liaqat (2022; also a later chapter version), South Asian Transhumanist Posthuman Ontologies: The Relationship between Vehicle Art and Mind Uploading in Uzma Aslam Khan’s Trespassing – Kumar et al. (2024), Merging biological and artificial consciousness: A neuroscience perspective of whole brain emulation* – Piccinini (2026), The neurobiophysical substrate of consciousness – Gao (2026), Asymmetrical replacement and the limits of functionalism: a reverse thought experiment – Wang (2026), Colleague Skill: an attempt at distillation and mind uploading BOOK CHAPTERS & ENCYCLOPAEDIA ENTRIES: – Geraci (2013), Mind Uploading – Szpyt (2020), Copyright Challenges Concerning the Development of Mind Uploading – Mercer & Trothen (2021), Mind Uploading: Cyber Beings and Digital Immortality – Sorgner (2021), Transhumanism Without Mind Uploading and Immortality – Jansen (2022), Ich und mein digitales Selbst* – Knaup (2022), Mind Uploading? Eine philosophische Kritik – Mühling (2022), Das iKalb, Relationalität und der ausgedehnte Leib: Theologische Perspektiven auf Post- und Transhumanismus – Klein (2022), Digitale Neugeburt als ein Anderer? Vom Geist-Körper-Dualismus zum Subjekt als Kulturprodukt – Wissinger & Wang (2023), Mind Uploading in Artificial Intelligence* – Alter, Howell & Kind (2023), Mind Uploading – Rosenthal (2024), Whole Brain Emulation – Inbaraj & Ravikumar (2024), Encountering Disability through Mind Uploading: A Transhumanist Reading of Richard A. Morgan’s Altered Carbon – Castro (2024), What Neurohacking Can Tell Us About the Mind: Cybercrime, Mind Upload and the Artificial Extended Mind – Gal-Or (2025), LKM Collective, Mind Uploading & Cloud AI – Percy (2026), Machine Consciousness and Mind Uploading – Raime & Misron (2026), Beyond Human Potential: Integrating Mind Uploading and AI for Enhanced Productivity in Malaysia’s Workforce → Access to the complete Seele digital collection would also cover the Jansen, Mühling and Klein chapters listed above. PREPRINTS & WORKING PAPERS: – Panin (2017), Philosophy of Mind Uploading. Subjectivism vs. Objectivism – Fernandes (2019), From Birth to the Grave in the New Age: The Challenges of Whole Brain Emulation in the Portuguese Legal Concepts of Personhood and Death – Ali (2025), The Unified Quantum-Consciousness Framework Integrating EQST-GP Physics with Veronica X Pro Architecture for Conscious AI – Pearson (2026), Consensual Mind-Cloning by Sparse Self-Capture MAGAZINE ARTICLES & ESSAYS: – Freitas (1996), The Future of Computers* – Kassan (2016), Uploading Your Mind Does Not Compute THESIS: – Gankhuu (2022), Ethics of Mind Uploading: Personal Identity CONFERENCE MATERIAL: – Sikau (2022), Rehearsing Posthumanism* (seeking an accompanying manuscript or transcript, if one exists) BOOK REVIEWS: – Henke (2023), review of Anna Puzio’s Über-Menschen and Jansen & Klein’s Seele digital – Bohrmann (2024), review of Jansen & Klein’s Seele digital Any leads would be much appreciated. And if you know of relevant work I've overlooked, please send it my way!!!
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Brainless clones are the future and the fewest have it on their radar.
Crazy, unexpected science news today: the brain is actually 2 colocated but independent organs that develop from 2 totally separate progenitor cells in early development. Big implications for some research areas (eg ALS) & for creating ethical brainless clones for transplant.
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LongevityBench is a genuinely useful contribution. But the headline result needs a caveat: fine-tuned 1–3B models vs. frontier models evaluated zero-shot with thinking disabled. That's not a fair fight. I'd love to see the same tasks with reasoning on and few-shot examples. Bet the bitter lesson applies here too. liquid.ai/blog/longevitybenc…
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The future of academic research papers
Thrilled that #paper2agent is published in @nature today! Scientific knowledge is traditionally stored in passive papers. Paper2Agent transforms papers into virtual authors that answer questions, apply its methods and collaborate w/ other paper agents to make new discoveries 🧵
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Say hello to Longevity AI models
In a new article published today on the cover of @CellCellPress, we obtained Liquid Foundation Model instances that establish state-of-the-art performance on biological longevity tasks, outperforming the best frontier models such as Gemini-3.1-Pro, GPT-5, and Claude Opus. In partnership with @InSilicoMeds, we built and released: > A comprehensive eval suite of 17 biological longevity tasks (i.e., LongevityBench), to assess whether a general-purpose language model can interpret aging data spanning clinical records, DNA methylation, transcriptomics, plasma proteomics, and genetic evidence. > LFM2-1.2B-Longevity and LFM2-2.6B-Longevity: two compact models specialized for interpreting structured aging data across these tasks. These results are important! 🧵
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Constantin retweeted
We just welcomed 35 exceptional founders and researchers into our home, and are now watching the future being built under our own roof. Closed-loop autonomous laboratories, dexterous robotics for unstructured environments, synthetic limb extensions for amputees, plasma guns to shoot down drones, and more. Cohort 2.f
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There will be no AI slowdown
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People keep misunderstanding this. I CONTRIBUTED to Bostrom’s Superintelligence book and he thanks me by name in the foreword. I was thinking about AI safety long before 2014.
Elon Musk posted this back in 2014 after reading Nick Bostrom’s Superintelligence: “Worth reading Superintelligence by Bostrom. We need to be super careful with AI. Potentially more dangerous than nukes” That was more than 12 years ago....long before the current AI boom The book explores what happens when machine intelligence surpasses human intelligence, the existential risks that follow and the enormous challenge of keeping superintelligence aligned with humanity Elon was sounding the alarm on this years before AI safety became mainstream....when most people barely understood what superintelligence even meant Today we now have a clear understanding that AI will become the most powerful technology humanity has ever created Making sure it remains aligned with humanity matters more than anything else
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Constantin retweeted
Replying to @beffjezos
I’ve already been to Berghain twice, but declined the third time when they had rainbow peace messaging in giant letters on their wall, which was lame
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Constantin retweeted
Replying to @kevinnbass
Dario is right that there should be some oversight. Peer review of AI by competitors is the right way to start this off.
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Constantin retweeted
Yes, this result cost millions of dollars. But remember that when @OpenAI announced o3 it cost ~$500,000 to score 87.5% on ARC-AGI 1. Today, Astra scores higher for ~$20. In 2025 it took us and GDM an enormous amount of compute to achieve IMO gold. For the 2026 IMO, anyone with a $20/month ChatGPT subscription could do it. Massively scaling test-time compute gives us a glimpse of the future. I believe that a year from now everyone will have an AI at their fingertips capable of solving problems of this caliber.
We’re sharing a solution to the Navier-Stokes Millennium Prize Problem, one of the deepest problems at the frontier of mathematics. The proof was produced by a group of agents, using an OpenAI next-generation model significantly more capable than GPT-6 Astra. The problem concerns whether the description of smooth three-dimensional fluid motion modeled by the Navier-Stokes equations can break down. It has remained unresolved for roughly 90 years.
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Constantin retweeted
I resigned from Anthropic today. I spent the last three years doing pretraining research at both OpenAI and Anthropic. Neither company is acting responsibly. They are racing straight to self-improving superintelligence and gambling with our lives. More thoughts below.
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Joining @shipfr8 was not on my bingo card this year…
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Constantin retweeted
Biggest myths I’ve come across in AI × bio: “There isn’t enough data” Biology already has vast datasets. The real challenge is identifying the questions that matter and getting the data needed to answer them. “Our historical dataset is our moat.” Historical datasets lose value as models absorb public knowledge; the real moat is generating high-quality answers to new questions on demand.
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