“We were previously blind, but now we see.”
For clinicians and patients, navigating leptomeningeal metastases (LM) diagnosis has historically been one of oncology’s steepest hurdles. Symptoms can masquerade as almost anything from persistent headaches and gait disturbances to double vision or auditory sensations. When relying solely on subjective history and qualitative imaging LM patients face the risk of their disease going undetected or misdiagnosed.
In our debut video of the CNS Cancer Clinical Perspectives series, Dr. Peter Forsyth shares insights into the qualitative limitations of standard imaging and clinical suspicion, biological complexity of the CSF compartment, and urgent necessity of precise molecular testing to inform clinical trials and targeted therapies.
As we look ahead to @NeuroOnc's #SNO2026 Annual Meeting next month, $CNSY is proud to champion these vital conversations alongside the launch of our next-generation CNSide® NGS capabilities.
Watch Dr. Forsyth’s perspective in the video below or on YouTube: bit.ly/4zZfXuJ
Follow $CNSY and @CNSideDx for upcoming episodes in the CNS Cancer Clinical Perspectives series.
$CNSY announced that a poster presentation of interim data from its ongoing ReSPECT-LMM multidose study of REYOBIQ™ will be presented at @NeuroOnc's 31st Annual Meeting and Education Day, taking place November 12–15, 2026, at the Pennsylvania Convention Center in Philadelphia.
The poster will report interim safety, dosimetry, CSF tumor cell enumeration, and individual treatment course data on the first ten patients from the multidose ReSPECT-LMM study.
Cerenome will also host a sponsored symposium at #SNO2026, featuring: Dr. Michael Youssef, Dr. Andrew Brenner, and Dr. Priya Kumthekar.
Learn more about the upcoming poster presentation and symposium here: bit.ly/4eXKxN9
RSVP for the symposium: bit.ly/4sp542C
@CNSideDx
$CNSY’s new CNSide® CSF Molecular Profile tests are officially available to U.S. clinicians!
@CNSideDx's Tumor Cell Enumeration (TCE) test gives clinicians a reliable way to detect and track tumor cells in the CSF, and now the expanded platform with CNSide® CSF Molecular Profile tests marks an evolution from detection to deep molecular actionability. CNSide now expands beyond cell enumeration to complementary, comprehensive DNA and RNA profiling from cerebrospinal fluid, covering primary CNS tumors, brain metastases, and hematologic cancers.
This marks a major step forward in delivering liquid biopsy precision to patients facing severe CNS malignancies.
Hear President and General Manager of CNSide, Russell Bradley, speak further to our effective approach and technology in the video below and read the full launch announcement here: bit.ly/3VTV6Kx
Last week, the CNSide team hit an extraordinary milestone: 10 patient kits received in one day! This incredible news combined with the launch of the NGS-based Molecular Profile tests is a testament to our dedicated lab team’s work.
🔗 bit.ly/3VNfrBe
@cerenome $CNSY
Starting October 12, physicians in the U.S. can order the following CNSide® CSF Molecular Profile tests:
- CNSide® CSF Molecular Profile - Solid Tumor (DNA & RNA)
- CNSide® CSF Molecular Profile - Hematologic Malignancies (DNA & RNA)
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Read the snapshot of the peer-reviewed study by Onoichenco et al. in Neuro-Oncology Advances: hubs.la/Q04yQQT20
#NeuroOncology #LeptomeningealDisease #LeptomeningealMetastases #CSF #LiquidBiopsy #CNSide #PrecisionOncology
CNSide® now holds contracted reimbursement coverage representing approximately 158 million covered lives nationwide.
Read more in our Press Release: hubs.la/Q04y0llz0
#CNSide #NeuroOncology #Diagnostics #PatientAccess #LeptomeningealMetastases #GetinsideCNSide
For patients with LM, tracking disease over time can be challenging. However, serial CSF monitoring may provide additional insight into disease burden and treatment response.
Read the snapshot of the case study by Pelletier et al. in Cureus: hubs.la/Q04xML-K0
This clinical data highlight is from a prospective UCSF study of patients with metastatic breast cancer and leptomeningeal metastases (LM) and shows why looking directly at the CSF matters.
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At our recent symposium at the SNO/ASCO CNS Mets Conference, leading experts in neuro-onc explored what that future could look like from CSF-based diagnostics & molecular profiling to AI, data analytics, & emerging therapies
Watch the full recording: hubs.la/Q04w_2K70
Join us at the 2026 SNO/ASCO CNS Metastases Conference for an important discussion on the evolving management of leptomeningeal metastases.
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Medical Mutual has signed a regional coverage agreement for the CNSide® CSF TCE assay, providing access to ~1.2 million covered lives across Ohio and Kentucky and increasing CNSide's total contracted coverage to approximately 127 million people.
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We're excited to share that CNSide is expanding its capabilities through a new collaboration with Genomic Testing Cooperative to integrate next-generation sequencing (NGS) into the CNSide® CSF assay platform.
About CNSide: cnside-dx.com/?utm=source_so…
#CNSide #NeuroOncology #CSF #NGS
$PSTV announces a collaboration to integrate @GenomicTesting Cooperative’s next-generation sequencing (NGS) technology into the @CNSideDx cerebrospinal fluid (CSF) assay platform.
The collaboration advances $PSTV's three-pillar CNS oncology strategy:
- Targeted radiotherapeutics led by REYOBIQ™ (rhenium Re186 obisbemeda)
- Precision diagnostics anchored by the CNSide CSF platform
- AI-enabled data analytics through the Company’s strategic partnership with Ephemeral Technologies
Full press release here: bit.ly/4vuCU6f
The latest NCCN Guidelines for CNS Cancers continue to recognize the importance of CSF analysis in the diagnosis and management of LM
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#NeuroOncology #LeptomeningealMetastases #CNSide #PrecisionDiagnostics #Oncology #ClinicalDiagnostics #CancerCare $PSTV
CNSide Diagnostics is exhibiting at Best of American Society of Clinical Oncology (@ASCO) in Dallas, Texas this weekend.
About CNSide: hubs.la/Q04nZnws0
The CNSide® CSF Tumor Cell Enumeration (TCE) CSF test is covered for approximately 126 million commercial lives, representing significant progress in expanding access for patients who may benefit from advanced CSF-based diagnostic testing.
Learn more: hubs.la/Q04ngW9-0
Coverage Update: CNSide® has expanded access by about 45.4 million covered lives through the recently secured Elevance Health agreement. This milestone increases CNSide’s total covered lives to approximately 126 million. $PSTV
CNSide Diagnostics has launched a new Patient Financial Services section on our website, designed to help patients and caregivers access information about coverage, reimbursement support, and financial assistance resources related to CNSide testing.
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Thank you to everyone who connected with us at Best of ASCO in Austin. Increasing awareness and education around #LeptomeningealMetastases (#LM) remains critically important, as LM continues to present significant diagnostic and treatment challenges for patients and clinicians.
.@CNSideDx's President and General Manager, Russell Bradley, exhibited at Best of @ASCO in Austin, TX this weekend, focused on raising awareness for Leptomeningeal Metastases (LM).
LM is a serious and often under-recognized complication of advanced cancer that occurs when cancer spreads to the membranes surrounding the brain and spinal cord, underscoring the need for greater awareness and education within the oncology community.
At the meeting, he highlighted how the CNSide® platform is helping advance the diagnosis and management of LM through innovative cerebrospinal fluid (CSF) analysis designed to support more informed clinical decision-making.
Learn more about CNSide: cnsidedx.com
CAP has awarded accreditation to CNSide Diagnostics based on the results of a recent live inspection as part of the CAP’s Accreditation Programs.
Press Release: hubs.la/Q04k0-jR0
About our lab: hubs.la/Q04k0-kM0
#CAPAccreditated #CNSCancer #GetInsideCNSide

























