@CKellendonk

Neuroscientist, Psychiatry, Columbia University, New York. Likes family, birds, music and wine & food.

 New York, NY
kellendonklab.org
Joined February 2019
  • Tweets50
  • Following154
  • Followers577
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Christoph Kellendonk retweeted
Katie Langin@k_langin16 Dec 2023
An NIH advisory group announced today that they're recommending the agency boost its minimum #postdoc salary to $70,000, up from the current $56,484. Many postdocs feel "underpaid and overworked," a co-chair said. My latest for @ScienceInsider: science.org/content/article/…

NIH advisory group recommends $14,000 boost in postdoc pay

Researchers shouldn’t be in postdoc positions for more than 5 years, the group also suggests

science.org
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Research Assistant (Columbia University, NYSPI - New York) We are looking for a Research Assistant to join our lab at Columbia University and the New York kellendonklab.org/ Experience with the handling of rodents is preferred. If interested e-mail: ck491@cumc.columbia.edu
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Great manuscript with relevance for schizophrenia.
Torfi Sigurdsson@TorfiSigurdsson15 Nov 2023
New paper from the lab! We show how a deficit in attenuating self-generated sounds observed in schizophrenia patients is caused by a major genetic risk factor for the disease, and examine the underlying mechanisms: nature.com/articles/s41467-0…

Altered corollary discharge signaling in the auditory cortex of a mouse model of schizophrenia...

Nature Communications - Schizophrenia patients are impaired in attenuating responses to self-generated sensory input. Here, the authors reveal the same sensory deficit and reduced corollary...

nature.com
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Great summary, Marie. It was a pleasure to collaborate with you and everybody else.
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Christoph Kellendonk retweeted
Cecilia Flores@cfloreslab7 Jul 2023
How does an experience in adolescence produce vulnerability in some individuals, but the very same experience can have no effect on others? I am super excited to share our new study doi.org/10.1038/s41467-023-3… 1/6

Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice

Nature Communications - Adolescent drug use augments psychiatric risk. Here the authors show that abused drugs dysregulate adolescent Netrin-1/DCC signaling, triggering ectopic long-distance...

nature.com
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Christoph Kellendonk retweeted
C. Savio Chan@csaviochan19 Jun 2023
The external pallidum in the basal ganglia plays roles in both motor and non-motor functions. The literature is rapidly evolving but confusing. A critical review is needed—check this out! Hope you’ll find this helpful! rdcu.be/deSSQ nature.com/articles/s41593-0…
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Christoph Kellendonk retweeted
Vikaas Sohal@sohallab26 Apr 2023
How does prefrontal cortex switch from maintaining to updating behavioral strategies & what are the origins + functions of gamma synchrony? Our new paper led by @kathleencho reveals surprising answers to these long-standing questions! A thread… nature.com/articles/s41586-0…

Long-range inhibition synchronizes and updates prefrontal task activity

Nature - Rule-shift behavioural experiments in mice demonstrate that callosal projections of parvalbumin-expressing neurons switch prefrontal circuits from maintenance mode to rule-learning mode by...

nature.com
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We are looking for a lab manager at NYSPI/Columbia Psychiatry in New York City: indeed.com/viewjob?jk=cae56a…
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Sarah Canetta's paper on the importance of adolescent PV activity for adult PFC function is out. Great collaboration with Sarah and @dr_alexharris : elifesciences.org/articles/8…

Mature parvalbumin interneuron function in prefrontal cortex requires activity during a postnatal...

Prefrontal PV interneuron activity during development is necessary for prefrontal circuit maturation, supporting adult prefrontal network function and cognitive flexibility.

elifesciences.org
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Join us Thursday, October 6th! Discovery and Disease - The Evolution of Molecular Pharmacology pharmacology.cuimc.columbia.…

Discovery and Disease - The Evolution of Molecular Pharmacology

Save the Date Discovery and Disease - The Evolution of Molecular Pharmacology A celebration of the 50-year career of Michael R. Rosen, M.D.

pharmacology.cuimc.columbia.edu
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Christoph Kellendonk retweeted
Lindsay Hayes@Lindsay_4c28 Sep 2022
It’s here! nature.com/articles/s41586-0…
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We are looking for a Post Doc to join our lab at Columbia University to study thalamo-cortical/striatal circuitry in the context of schizophrenia: kellendonklab.org/ Experience in vivo physiology/imaging preferred. Please e-mail: ck491@cumc.columbia.edu. Please retweet.
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Kelly Martyniuk's manuscript on dopaminergic regulation of striatal acetylcholine levels during behavior is out elifesciences.org/articles/7…
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Beautiful Paper from Abigail Kalmbach, Peter Balsam & Eleanor Simpson on dopamine encoding of real time reward availability. nature.com/articles/s41467-0…

Dopamine encodes real-time reward availability and transitions between reward availability states...

Nature Communications - Dopamine in the ventral striatum conveys a complex reward-associated signal. This study demonstrates how dopamine reflects sustained reward availability, and rapidly signals...

nature.com
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Check out our new lab web page. kellendonklab.org
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Christoph Kellendonk retweeted
Nature Neuroscience
@NatureNeuro19 May 2022
Inhibiting the mediodorsal and midline #thalamus in adolescent mice leads to lastingly decreased excitatory drive onto PFC neurons and PFC-dependent cognitive deficits during adulthood New from @CKellendonk, @dr_alexharris, @ljbenoit and colleagues nature.com/articles/s41593-0…
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Christoph Kellendonk retweeted
Jonathan A Javitch@JavitchLab27 Apr 2022
Another amazing collaboration with @TheBlanchardLab! Thanks to them and all of our other fantastic collaborators without whom this work would not have been possible.
Wesley B. Asher@WesleyBAsher27 Apr 2022
Our paper “GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision” is out today! We use single-molecule FRET imaging and other biophysical approaches to explore the structural dynamics of β-arrestin1 activation upon binding GPCRs. (1/6)
Schematic of β-arrestin binding to an agonist-activated GPCR in the plasma membrane.

ALT Schematic of β-arrestin binding to an agonist-activated GPCR in the plasma membrane.

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Join our labs at Columbia University/NYSPI in NYC as Lab Manager. columbiapsychiatry.org/profi… columbiapsychiatry.org/resea… Responsibilities: oversight lab operations, supply purchasing, inventory management. Contact: ck491@cumc.columbia.edu or jaj2@cumc.columbia.edu Please retweet.
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Christoph Kellendonk retweeted
Ali Salahpour@SalahpourAli25 Apr 2022
It is with much sadness that we learned about the passing of our mentor, Marc Caron. Deepest condolences to his family. A 2009 picture where we had a go-away party at his house. Always generous, always gracious. He touched and influenced many lives and will be dearly missed.
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We look for a Post Doc to join our lab at Columbia University/New York to study thalamo-cortical interactions: columbiapsychiatry.org/resea… pubmed.ncbi.nlm.nih.gov/?ter… Experience in mouse slice or in vivo physiology preferred. Please e-mail: ck491@cumc.columbia.edu. Please retweet.
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