@chrisahern
 Midwest, USA
ahernlab.com
Joined January 2009
  • Tweets242
  • Following221
  • Followers321
2Media
Chris Ahern retweeted
Leah@LeahEDSCN2A12 Oct 2022
A club none of us ever wanted to join yet here we are. Fighting hard every day for a better future. #cureSCN2A
FamilieSCN2A@FamilieSCN2A12 Oct 2022
#SCN2A #CureSCN2A #7thBirthday
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This #preprint by @GraceGalles, @chrisahern and colleagues at @OregonState, @UofIllinois and @uiowa has recently been reviewed by @BiophysicsColab You can read the report here: sciety.org/articles/activity… biorxiv.org/content/10.1101/…

Tuning aromatic contributions by site-specific encoding of fluorinated phenylalanine residues in...

The aromatic side-chains of phenylalanine, tyrosine, and tryptophan interact with their environments via both hydrophobic and electrostatic interactions. Determining the extent to which these...

sciety.org
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Yet another company focused on #tRNA therapies launched yesterday: hC Bioscience, with $24 million and Craig Mello on the SAB. It is a good time to revisit the deep dive I wrote on this emerging tRNA technology back in Sept. cen.acs.org/pharmaceuticals/…

tRNA therapies could help restore proteins lost in translation

A new class of therapies based on transfer RNA could treat forms of cystic fibrosis, muscular dystrophy, genetic epilepsies, and more

cen.acs.org
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Ryan Hibbs, Associate Professor at UTSW and @ucsdbms @UCSDPharm alumnus, is presenting the Chemistry and Biochemistry seminar this Friday 👇
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Fantastic news - major congrats to Leah and the SCN2A Foundation
Leah@LeahEDSCN2A3 Nov 2021
This is an incredible opportunity for us to advance our mission! We are incredibly grateful to @ChanZuckerberg #cureSCN2A
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Chris Ahern retweeted
Leah@LeahEDSCN2A13 Oct 2021
7.5 years ago I started the very first #SCN2A support group. We have grown to almost 1,000 families from around the globe! Happy 6th birthday @FamilieSCN2A!
FamilieSCN2A@FamilieSCN2A13 Oct 2021
"On the eve of the Foundation's 6th birthday I reflect back on the day I started the Facebook support group. I knew was that there had to be other parents out there dealing with this diagnosis and I wanted to talk to them.” @LeahEDSCN2A #SCN2A
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Happy birthday to #LaskerLaureate Bertil Hille! Hille was recognized for his work on #ionchannels, which govern the electrical potential of membranes, generating nerve impulses and controlling muscle contraction, cardiac rhythm, and hormone secretion. ow.ly/SPfX30lRPuy
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#BiPOfficialRollout | #IntegrativePhysiology #BlackinPhysiology #BiPHomecoming2021 #BiPWeek2021 @phdgprotein86
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For another perspective on C-type inactivation. Check out this JGP paper from @BenoitRoux6 and @eperozo_ rupress.org/jgp/article/150/…
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Wow! Another structure of C-type inactivated state of Shaker type channel. Congrats to Francis Valiyaveetil and the team!
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Xenon Pharmaceuticals Announces Positive Topline Results from Phase 2b ‘X-TOLE’ Clinical Trial of XEN1101 for the Treatment of Focal Epilepsy ow.ly/nGGI50GlgOv
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Slow inactivation is renewed! Great to see these open/inactivated structures along with the Shaker W434F from @kenton_swartz biorxiv.org/content/10.1101/… @indolenitrogen

Structure of the Shaker Kv channel and mechanism of slow C-type inactivation

Voltage-activated potassium (Kv) channels open upon membrane depolarization and proceed to spontaneously inactivate. Inactivation controls neuronal firing rates and serves as a form of short-term...

biorxiv.org
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Chris Ahern retweeted
Leah@LeahEDSCN2A20 Sep 2021
Such promising work! @TevardB @chrisahern
Heidi Grabenstatter@PatientIntv20 Sep 2021
How @TevardB is using suppressor tRNA therapies to blow through the "stop signs" in instances of premature stop codons to enable appropriate translation of proteins. cen.acs.org/pharmaceuticals/…

tRNA therapies could help restore proteins lost in translation

A new class of therapies based on transfer RNA could treat forms of cystic fibrosis, muscular dystrophy, genetic epilepsies, and more

cen.acs.org
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Want to learn more about Voltage-Gated Sodium Channels #ionchannels? Join us on Sept. 28, 2021, with the inaugural seminar by Dr. Nieng Yan @NiengYan "Close a voltage-gated sodium channel by a door wedge" - more info on sodiumchannelseminars.org/ co-organized @LampertLabRWTH & us.
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Exciting times for @KelleyLabs!
Weinberg College at Northwestern@WeinbergCollege23 Aug 2021
Shana Kelley, a pioneer in translational bioanalytical research, and Ted Sargent, a renowned researcher in nanotechnology, join Northwestern. @WeinbergCollege @NUChemistry @NorthwesternEng @IINanoNU @NorthwesternU Learn more: wcas.nu/3zeyCnc
Left to right: Professor Shana Kelley and Professor Ted Sargent

ALT Left to right: Professor Shana Kelley and Professor Ted Sargent

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Hyde Park is glowing 🌆 📷 @brettbeyer
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Join us Sept. 30 for next webinar presented by Dr. Ishmail Abdus-Saboor, Asst Prof at @Columbia. He'll discuss findings from efforts to uncover a behavioral map of sensory-vs-motivational pain in mice. #drugdiscovery #translationalresearch #painresearch attendee.gotowebinar.com/reg…
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On behalf of twitter-less Dr. Dave MacLean: the MacLean Lab at @urochestermed is looking for a postdoctoral candidate! Attached is a letter with more info. TL;DR talented scientists with backgrounds in genetic code expansion, ephys and/or fluorescence techniques should apply!
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