Norman & Cecilia Yip Professor in #BioinorganicChemistry. Research on #Metallobiology, #Metallomics, #AntimicrobialResistance (AMR), Antiviral Agents (#SARS)
Hong Kong
Joined April 2012
- Tweets295
- Following646
- Followers1K
- Likes1.7K
Pinned Tweet
At last, metallodrug ranitidine bismuth citrate as a novel antiviral agent for treating COVID-19 infection. The work was just published in Nature Microbiology! A real collaboration with biologists and clinicians. Medicinal inorganic chemistry is important (I like it).
"CAR-T Meets CyTOF: High-throughput Cytokine profiling offers new insights for predicting CRS risk". Please read our paper in @ChemicalScience which was featured in the front Cover (doi.org/10.1039/d6sc03656b)! Well done Keyuan👍
3
13
371
Very delighted to read our recent perspective of "bismuth's new applications against antimicrobial resistance and coronaviruses" in the first issue of Acc Chem Res (@ACSPublications) and to be featured in the front cover (#MyACSCover): pubs.acs.org/doi/pdf/10.1021…
Heartfelt congratulation to Peter Sadler for "2025 Blaise Pascal Medal in Chemistry", for his pioneering contributions to bioinorganic chemistry (@SBIC) & his lifelong dedication to advancing metals in medicine👍!
It is truly an overdue recognition to bioinorganic chemistry.
What a fantastic Cover Art (for the fight against antimicrobial resistance (AMR) in @J_A_C_S , #MyACSCover! Thanks Mr. Li Zhang and Dr. Chenyuan Wang for designing the cover image! Please download the paper (open access) for details at pubs.acs.org/toc/jacsat/147/…
Dear junior scientists on biological inorganic chemistry @SBICofficial we provide a platform for you to show your breakthrough work👍! You can not afford to miss the chance
SBIC Early Career Researcher Mini-Symposium
Empowering the Next Generation of Biological Inorganic Chemists
How to Apply
Selected speakers will be chosen from their submitted ICBIC-21 abstracts.
icbic21.org/abstracts
Abstract Submission Deadline: 27th April, 2025
Pleased to share our Perspective in @J_A_C_S entitled "Metal-based approaches for the fight against antimicrobial resistance (AMR)": pubs.acs.org/doi/full/10.102…
Our new arsenal against AntiMicrobial Resistance published in @NatureMicrobiol: Bismuth-based drugs/compd effectively sensitize Pseudomonas aeruginosa to multiple antibiotics by disrupting iron Ourhostasis. Bismuth chemistry is amusing! @OscarKuipers1 @rubencebrian @hku_science
Happy to see our collaborative work with Xinming Yang on "Clinically used drug arsenic trioxide (As2O3) targets XIAP & overcomes apoptosis resistance in an organoid-based preclinical cancer model". The paper is featured in the cover of @ChemicalScience (2024, 15, 8311).
Feel honored to receive this Innovator Award, and thank all members in the group and collaborators in medical school @hkumed !
@HKU_Chemistry's Prof Sun Hongzhe (@chemhsun) received the #HKU Innovator Award 2023 for his impactful innovations! Prof Sun & his team created a cocktail therapy to suppress the replication of the SARS-CoV-2 virus, attracting attention from the media & pharmaceutical companies.
If you missed @HKUniversity for your first degree, you can not afford to miss the Master degree (and Ph.D). Welcome to join @HKU_Chemistry!
Check out @HKU_Chemistry's new Master of Science Programme - 1.5 years of intensive training that will elevate your career prospect empowered by Chemical Technologies!
#Education #HKU #Chemistry
Hongzhe Sun at HKU retweeted
Nsp14/nsp10 complex is an authentic target of bismuth-based allosteric inhibitors against pan-SARS-CoV-2 infection. #ACSInfectiousDiseases
go.acs.org/6T6
You are sincerely invited to attend the symposium on Nov. 3-5, 2023 at @HKUniversity @hku_science
The following conference is just around the corner! ukhksymposium.hku.hk/
Free registration, submit your abstracts asap!
Rapid emergence of @AMR pathogens highlights the urgent need to develop novel @AntibioticsThe. We proposed a dual Trojan Horse strategy, i.e. metallo-sideromycin (e.g. Bi(III)) for coping with AMR. It works beautifully. Please read the @NatureComms paper (nature.com/articles/s41467-0…)
Dalton Horizon Prize (2023): "Bismuth cure for COVID-19". We are extremely delighted to be recognised by RSC @DaltonTrans. It is a reward of persistence on our original and cutting-edge research with potential to improve human health. @SBICofficial @HKU_Chemistry @Metallomics
At last, protein targets of Cr(III) in cells were uncovered by an integrative metallo-proteomics approach (@NatureComms )! Mitochondrial ATP synthase as a direct target of Cr(III) to ameliorate hyperglycaemia stress. Please read details at nature.com/articles/s41467-0…
Happy to see our latest work in @JBIC_Journal on the use of gold(I) drugs as a colistin adjuvant in the fight against infections by @ANTI_SUPERBUGS using MCR‑1 producing bacteria as an example!
From our own Associate Editor @chemhsun: Fighting colistin resistance by combination therapy with Au drugs, after pre-activation by thiols. Exciting in more than one way, and with evident clinical application!
rdcu.be/c4zHy
Beautiful work on prediction of metal-binding sites in proteomes using machine learning (ML) by Chu' group at PKU (@ChuWangPKU)
Happy new year 2023! Glad to share our recent paper at Nature Chemical Biology @nchembio on predicting metal-binding sites in proteomes using machine learning. You can read it at rdcu.be/c2DI1
4
765
Do you want to do your graduate study (Ph.D/ M.Phil) in the University of Hong Kong (and in the beautiful city of Hong Kong)? Please apply for it. The deadline is Dec. 1, 2022 (ONE week left).
🔔🔔🔔LAST CALL! Main Round Application for HKU PhD and MPhil Admission 2023-24 will close on Dec 1, 2022. Successful candidates can enjoy prestigious scholarship packages to support research postgraduate studies. Apply now!
Details 👉 gradsch.hku.hk
We urgently need your help to support "Inorganic Chemical Biology" and "Bioinorganic Chemistry".
We're excited to announce an upcoming themed collection on the Chemical Biology of Metals! Find out more, and how to submit your work, on our blog: blogs.rsc.org/cb/cbmet23-cal…
ALT A banner depicting the Guest Editors of the "Chemical Biology of Metals" collection, with a deadline of 6 March 2023 and a link to rsc.li/rsc-chembio
Our feature article entitled "Metal-based strategies for the fight against COVID-19", published in @ChemCommun (58, 7466). Hope 'Metals-in-Medicine' can play a role to end the pandemic. pubs.rsc.org/en/content/arti…
