Studying how complex patterns form life @NorthwesternU |Developmental Systems Biology| Morphogenesis | RTK/ERK | Previously @iitdelhi | iGEM
Chicago, IL
Joined March 2018
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Past week was stunningly amazing🥳:
1. Our paper (I'm 2nd author) got accepted @Nature [much more to come]
2. Got 1st prize in poster presentation @uofcincy
3. Ended with my dance (bhangra) performance @CincyChildrens
@diljitdosanjh
Chandel Angad retweeted
Evidence suggests that transcriptionally similar cells can be functionally diverse
go.nature.com/3MOHJqp
Chandel Angad retweeted
Required reading for cell biologists to get a sense of basic statistical principles!
nature.com/articles/s41556-0…
Chandel Angad retweeted
Why would anyone want to be a scientist? There are the pleasures of:
1. Having the initial idea or insight,
2. Watching the idea develop into new experiments or a new model, and
3. Telling others.
Martin A. Schwartz also talks about this on the podcast: podcasts.apple.com/us/podcas…
Check out this amazing work from our lab . Many congratulations to Eslim!
Exciting new findings from our lab! ⏳🐟
In our latest @NatureComms paper, we show that DeltaD—not just DeltaC—drives Notch signaling in zebrafish, reshaping our understanding of segmentation clock dynamics! 🔬✨
Paper: rdcu.be/ec2Yz
Excited to present in the trainee series.
I’ll be presenting on ‘Oscillators and gradients in developmental biology’
📣Join us this Tuesday @ 9AM the Baldwin Auditorium for a Trainee Seminar, presented by @ChandelAngad , Predoctoral Fellow in the @OzbudakLab 🧬📚
Chandel Angad retweeted
📣Join us this Tuesday @ 9AM the Baldwin Auditorium for a Trainee Seminar, presented by @ChandelAngad , Predoctoral Fellow in the @OzbudakLab 🧬📚
Check out this amazing piece of work by our lab 👇
Congratulations to everyone especially to @didarsaparow for his first author work.
🌟 New Paper Alert! 🚨
How does a developing embryo know where to place somite boundaries? 🦴🐟
Our latest study authors.elsevier.com/a/1kATe… in @Dev_Cell reveals a missing piece of the puzzle involving ERK oscillations and the segmentation clock (nature.com/articles/s41586-0…)
(1/)
Chandel Angad retweeted
This week has been all about podcasts! It was a pleasure to reflect on my IIT Delhi experience, the early days of settling in, how consistency is key to growth, and my journey navigating the research environment beyond IITD. Hope you enjoy listening to it. youtube.com/watch?v=l_vyBT1j…
🚀 Excited to chat with Prof. @ankurg90 from @CUEngineering about how animals create stunning patterns and their research on ion flow in supercapacitors! We also explore his inspiring journey in science. Don't miss it! #Hindi #Science
👉 Watch here
youtube.com/watch?v=JxWeArbl…
In Part 1: We explore his groundbreaking research, discussing how Turing patterns create the beautiful patterns we see on animals. Additionally, we delve into his innovative theory on ion flow in capacitors.
In Part 2: We trace the journey of a scientist—Prof. Gupta shares his inspiring experiences from childhood, his journey as an IITian, through his PhD at MIT, and his postdoctoral research at Princeton.
#IIT #MIT #Princeton
Chandel Angad retweeted
🚨News alert !! Honored to be endowed with Robert Laughlin Rea Professor of Anatomy at Northwestern University!
Chandel Angad retweeted
📣Thrilled to announce the new postdoctoral & predoctoral departmental representatives: Bhuvan, Postdoctoral Fellow in the Gelfand lab and Chandel, Predoctoral Fellow in the Ozbudak lab!
@BuvanSR @volodya_gelfand @chandelangad @OzbudakLab
Chandel Angad retweeted
Preprints (cont.):
@EngertLab @MishaAhrens @alexbchen (Astroglial purinergic signaling/ Norepinephrine)
biorxiv.org/content/10.1101/…
@SeuntjensLab @CarolineZandeck (Killifish/ Telencephalon/ Growth/ Neural diversity) biorxiv.org/content/10.1101/…
@joachimgoedhart (EzReverse/ Color adjustment tool)
biorxiv.org/content/10.1101/…
Reviews & Perspectives:
#OlaLab @UniHeidelberg @LabSeyfried (Shear stress/ PI3K/ Vascular malformations)
jci.org/articles/view/172843
@CampasLab @a_boutillon (Physical mechanisms of morphogenesis)
journals.biologists.com/dev/…
@Sundar_Ram_07 (Developmental robustness/ Tissue morphogenesis)
portlandpress.com/biochemsoc…
@OzbudakLab @ChandelAngad @KemalKeseroglu (Oscillatory expression/ Embryogenesis)
journals.biologists.com/dev/…
Dr. Stephanie Telerman @Cambridge_Uni @ClaraMutschler (Glial plasticity)
cell.com/trends/cell-biology…
@AnnaMolofskyLab @CarolineScsGlia (Microglia/ Brain development)
sciencedirect.com/science/ar…
#YoderLab @NCState @AM_Connors (PFAS/ Immune function)
tandfonline.com/doi/full/10.…
@JessPlavicki @Dr_Miche_Fishe (Fertility research/ Reproducibility)
sciencedirect.com/science/ar…
#YamahiraLab @Riis_Ryukyu @petyuratto (Oryzias hubbsi/ Reproductive isolation)
link.springer.com/article/10…
Protocols & Methods:
@AnaMValentim @sarasijorge (Cortisol measurements/ ELISA kit validation) sciencedirect.com/science/ar…
Please give a special thanks to Maddie Ryan (@madeline__ryan) & Charli Corcoran (@CharliCorcoran) for putting this digest and many others together! If you would like to thank the @ZebrafishRock team for their time & effort, you can buy us a cup of coffee at the link below. Every little bit keeps us caffeinated and motivated! We appreciate your support 🙂
🙏 ko-fi.com/zebrafishrock
And don't forget to check out our website: linktr.ee/zebrafishrock!
Fin!
5 of 5
Hey, Curious minds! Ever wondered how stem cells magically transform into the right cells at the right time? Or how nature creates beautiful patterns like somites? Explore the fascinating world of oscillatory Hes/Her genes in our review! #Science #STEM
Oscillatory control of embryonic development
In this Review, Angad Singh Chandel, Kemal Keseroglu & @OzbudakLab explore the diverse functional roles played by the oscillatory expression of bHLH family transcription factor Hes/Her genes and their targets:
journals.biologists.com/dev/…
ALT Figure 1: Synchronized clock expression during somite formation and the ‘clock-dependent oscillatory gradient’ (COG) model
Then, we discuss the gatekeeping role of their oscillatory expression in neurogenesis, myogenesis and pancreas development. It ensures proper embryonic development by regulating proliferation-to-differentiation switch of stem cells and progenitor cells.
Congratulations @KemalKeseroglu and @OzbudakLab. It was so much fun exploring the role of the genetic oscillators in embryonic development. Thanks @jtchieu for discussions and providing valuable feedback and thanks to Ben Caputo and Brady Cline for critical reading and editing.