@cflagospharma

Pharmaceutical Chemist, Molecular Craftsman, PhD

 Santiago-Chile
Joined March 2010
  • Tweets1.7K
  • Following1.9K
  • Followers575
66Media
Carlos F. Lagos retweeted
AFFI CHILE@AffiChileAug 3
📷 DECLARACIÓN PÚBLICA: La dispensación de medicamentos debe resguardar la seguridad de los pacientes y cumplir la normativa sanitaria. Frente a las gestiones que Mercado Libre estaría realizando ante autoridades chilenas, las organizaciones firmantes declaran:
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Desde Valdivia, investigadores e investigadoras descubrieron un mecanismo clave en las neuronas. El estudio, financiado principalmente por @anid_chile; vía Fondecyt, y publicado en Cell Metabolism; ayuda a entender cómo las neuronas se protegen del estrés oxidativo, un tipo de daño celular vinculado a enfermedades como el Alzheimer, el Parkinson y los accidentes cerebrovasculares. Este hallazgo abre nuevas líneas de investigación para comprender qué ocurre cuando estos mecanismos de protección fallan. 🔬
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🚨 BREAKING: IBM launches a free Python library that converts ANY document to data Introducing Docling. Here's what you need to know: 🧵
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📢 ¡Ya está disponible el Calendario de Convocatorias 2026 de ANID! Conoce y planifica la postulación a oportunidades de financiamiento para proyectos individuales y asociativos en investigación, tecnología, innovación y estudios de postgrado. Revisa las fechas clave en: anid.cl/calendario-concursos…
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Carlos F. Lagos retweeted
Boris Cherny
@bchernyJan 31
I'm Boris and I created Claude Code. I wanted to quickly share a few tips for using Claude Code, sourced directly from the Claude Code team. The way the team uses Claude is different than how I use it. Remember: there is no one right way to use Claude Code -- everyones' setup is different. You should experiment to see what works for you!
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Libgen, Sci-Hub, and Z-library had millions of pirated academic books and papers. So, they were shut down. We shouldn't use them anyway. We should help billion-dollar academic publishers get richer. Anyway, here's how to access these libraries: Don't do this!
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pubs.aip.org/aip/jcp/article…

apoCHARMM: High-performance molecular dynamics simulations on GPUs for advanced simulation methods

We present apoCHARMM, a high-performance molecular dynamics (MD) engine optimized for graphics processing unit (GPU) architectures, designed to accelerate the s

pubs.aip.org
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Carlos F. Lagos retweeted
Patrick Walters@wpwalters13 May 2025
New Practical Cheminformatics Post, "Useful RDKit Utils - A Mötley Collection of Helpful Routines" patwalters.github.io/Useful-…
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Carlos F. Lagos retweeted
BryanRoth
@zenbrainest7 May 2025
Wow, wow, wow!!! The structure of human sweetness cell.com/cell/fulltext/S0092…

The structure of human sweetness

A single taste receptor initiates our reactions to both sugars and artificial sweeteners, triggering a signaling process that drives our intense attraction to sweet foods. Single-particle cryo-EM...

cell.com
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For readers interested in siRNA therapies, here's a review nature.com/articles/s41573-0… rdcu.be/ef9IV
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Carlos F. Lagos retweeted
BryanRoth
@zenbrainest20 Mar 2025
Yuuge paper on #psychedelics The structural diversity of psychedelic drug actions revealed nature.com/articles/s41467-0…
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Carlos F. Lagos retweeted
CarlssonLab@CarlssonLab13 Mar 2025
Identifying ligands for therapeutic targets among billions of compounds is challenging! Can we search ultra-large chemical libraries more efficiently? Yes! Read about our docking/ML approach: nature.com/articles/s43588-0…

Rapid traversal of vast chemical space using machine learning-guided docking screens

Nature Computational Science - Combining conformal prediction machine learning with molecular docking, a method to efficiently screen multi-billion-scale libraries is developed, enabling the...

nature.com
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For readers interested in RNA-based medicines such as antisense oligonucleotides and siRNAs, here's a review discussing strategies to address challenges associated with their applicability, efficacy and safety profiles nature.com/articles/s41573-0… rdcu.be/eciEq
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Solo falta el 10%....muy muy cerca de la meta!!! Aun puedes ADQUIRIR TU ENTRADA PARA MAÑANA O HACER TU DONACIÓN crowdfunding.4id.science/ 🗓️ *Sábado 1 de marzo* ⏰ *Entre 12 y 20 horas* 📍 *Villa Rovereto, Laguna de Aculeo, Paine* Te esperamos!
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El último día de febrero se conmemora el día mundial de las #EnfermedadesRaras #PocoFrecuentes @rarediseaseday . En preparación para este día, compartiremos durante esta semana los resultados principales de nuestro trabajo de investigación colaborativa en el @ICIM_UDD et al.
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For readers interested in personalized therapeutics such as antisense oligonucleotides for ultra-rare diseases, this review from @irdirc discusses progress in the field and provides a roadmap for their development nature.com/articles/s41573-0… rdcu.be/ea4yG
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For readers interested in cancer immunotherapy, this Review in our February issue discusses opportunties and challenges in using vaccines for cancer prevention nature.com/articles/s41573-0… rdcu.be/eaNxo
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For readers interested in therapeutic strategies for Duchenne muscular dystrophy, here's a review nature.com/articles/s41573-0… rdcu.be/eaGft
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For readers interested in new epilepsy therapies in development, here's a comprehensive recent review nature.com/articles/s41573-0… rdcu.be/eaxv6
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Google just introduced an AI co-scientist. "To help uncover new, original knowledge and to formulate...novel research hypotheses...building upon prior evidence and aligned to scientist-provided research objectives and guidance." If it's half as good, it'll be revolutionary.
A screenshot of Google's AI co-scientist system design.

ALT A screenshot of Google's AI co-scientist system design.

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