Here to talk about shit that doesn't matter
916 // Sactown
Joined March 2009
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All diseases will be cured.
If you're blackpilling about the future, you're just not paying attention.
this might be my last normal tweet before biotech goes vertical
i'm not a whistleblower. I don't work at Lilly, Novo or any of the big labs
but there is a massive shift happening in human biology right now.
it's sitting in press releases and almost nobody reads them
the last 6 months alone:
- a once-daily pill roughly doubled median survival in metastatic pancreatic cancer (13.2 vs 6.6 months)
- a one-time gene editing infusion cut hereditary angioedema attacks 87%, and 62% of patients stayed attack-free and off all other prevention for 6 months
- a one-time gene edit for cholesterol dropped LDL up to 62%, and it held for over a year
- a personalized mrna vaccine beat keytruda alone in a 1,137 patient melanoma phase 3
- retatrutide hit ~28% weight loss in a phase 3
- an ai-designed drug entered phase 3
- a pill that regrows hair passed its second phase 3
- an immunotherapy that could let some rectal cancer patients skip surgery, chemo and radiation just got fda approved
- a man lived 271 days off dialysis on a pig kidney
- human cells were caught passing chromosome-sized chunks of DNA to their neighbors, and it changes how the neighbors behave
we are on the verge of an era where the human body is a software problem and the update cycle gets shorter everyday
stick around, it's going to get weird
bio/acc
This is actually why futures contracts were created in the first place, for farmers to be able to hedge against crop prices in years of drought or economic instability.
Seems the perfect way for people to use prediction markets that are all built on futures contracts.
An LA hospitality group runs 25 bars, many of them right by Dodger Stadium. Every extra playoff game means packed bars. An early exit means lost revenue they were counting on.
So they hedged it. They put $60,000 on Kalshi on the Dodgers *not* making the World Series.
The Dodgers lost the NLCS to the Brewers. The position returned nearly 2x, helping cover the playoff business that *never* came.
A Columbia law professor told Fortune it works like “a form of bespoke insurance.”
Read the full story here: fortune.com/2026/10/19/predi…
The market wants to pump so hard right now that it's actually insane. I don't think people are bullish enough
Clear example an Overton Window shift.
I spend a lot of time listening to people who seem schitzo. Spend enough time listening to schitzos and you start to distinguish who is schitzos vs just early to an Overton Window shift.
Stephen A. Smith publicly APOLOGIZES to Kyrie Irving after calling him "selfish" for refusing the COVID jab.
"Hindsight-wise, it didn’t make him stubborn or selfish. It made him BRAVE."
"I watched Dr. Fauci on Capitol Hill yesterday, and the person I thought about most was Kyrie Irving."
“Kyrie Irving stood out in my mind because of the heat that he was taking... He refused the vaccine. New York City's mandate made him ineligible for home games, and he linked his stance to people losing jobs over vaccine mandates."
“In my opinion, particularly hindsight-wise, it didn't make him stubborn or selfish. It made him brave. His willingness to stand up and say, ‘Nah, I'm not doing that.’
“It's just a time for reflection — to look at things differently.”
Kyrie gave up $11,400,000 in game checks during the 21-22 NBA season and a $100,000,000 extension with the Nets to be unvaccinated.
That cements his holdout as the largest financial sacrifice any athlete has ever made over an issue in history.
buttersutter retweeted
The birth years of Continental Congress members if the United States Declaration of Independence had been signed in 2026.
My freshman year roommate is posting shirtless AI photos of himself on facebook and people keep commenting on how good he looks
being a King's fan is wild because you can be 6-22 on the season and the arena still goes insane for a close game
whenever someone tells me they wear sunscreen everyday, this is the first thing I think about. You need to be spending more time in the sun to build up a tolerance.
