@brianmacgrory

Neurologist, Duke University School of Medicine @Duke_Neurology; @DCRINews; @UCDMedicine

 Durham, NC
Joined August 2013
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mayomagazine.mayoclinic.org/…

The Eyes Have It: Retinal Imaging Shows Promise for Transforming Care

Mayo Clinic researcher Oana Dumitrascu, M.D., is using retinal imaging and artificial intelligence to identify early signs of stroke, cognitive decline and Alzheimer’s disease.

mayomagazine.mayoclinic.org
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Brian Mac Grory retweeted
Gregg Fonarow MD@gcfmdAug 19
Replying to @HFSA
Honored to receive the 2026 HFSA Lifetime Achievement Award Thank you to the mentors, colleagues, and fellows who shaped this work, and to the patients who inspired it Grateful to @HFSA and proud of how far our field has come #HFSA2026 @DOM_UCLA @UCLAHealth
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Gregg Fonarow MD@gcfmdJul 13
🩻 Faster door-to-puncture too (84.4 vs 92.8 min) One 5–10s bolus 💥 instead of a 60-min infusion = smoother ED + transfer workflow Time is brain 🧠⏳ Warach et al. JAMA Netw Open. 2026;9(7):e2623260 📄 
#Stroke #TNK #NeuroTwitter
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Gregg Fonarow MD@gcfmdJul 13
🚨🧠 NEW in @JAMANetworkOpen: Tenecteplase beats alteplase on clock ⏱️ 📊 133,228 stroke patients | 2,092 US hospitals 
💉 Door-to-needle: 47.0 vs 52.7 min (adj −3.13) ⚡ 
🚑 Door-in-door-out: 108.3 vs 114.1 min (adj −5.94) 
🎯 DTN ≤30 min: 29.9% vs 20.4% (aOR 1.34) ✅
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Thrilled to share our AHA/ASA Scientific Statement on left ventricular dysfunction, stroke risk, and therapeutic implications. It was a lifetime honor to chair our outstanding writing group. Hope this informs care and inspires future research. ahajournals.org/doi/10.1161/…

Management of Patients at Risk of Ischemic Stroke With Left Ventricular Systolic Dysfunction in the...

Left ventricular (LV) systolic dysfunction, defined here as reduced LV ejection fraction ≤40% or left wall motion abnormality, is commonly found in patients with ischemic stroke. Although there is an...

ahajournals.org
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Shumei Man@ShumeiManMDMay 28
Replying to @gcfmd @Braindoc_MGH @kejoynt @VCI_EricSmith @StrokeAHA_ASA @American_Stroke @AHA_Research @AHAScience @HeartNews @brianmacgrory @DCRINews @DLBHATTMD
Thanks to @StrokeAHA_ASA and all coauthors for making this and prior publication possible to understand the actionable disparities in rural America! We hope to see changes soon! @gcfmd @Braindoc_MGH @brianmacgrory @DLBHATTMD ahajournals.org/doi/10.1161/…

Rural Hospital Performance in Guideline-Recommended Ischemic Stroke Thrombolysis, Secondary...

BACKGROUND: Existing data suggested a rural-urban disparity in thrombolytic utilization for ischemic stroke. Here, we examined the use of guideline-recommended stroke care and outcomes in rural...

ahajournals.org
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Gregg Fonarow MD@gcfmdMay 28
Terrific study by @ShumeiManMD @Braindoc_MGH @kejoynt @VCI_EricSmith @StrokeAHA_ASA @American_Stroke @AHA_Research @AHAScience @HeartNews @brianmacgrory @DCRINews @DLBHATTMD
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Brian Mac Grory retweeted
Gregg Fonarow MD@gcfmdMay 28
Compared with urban patients, rural patients with stroke had less inpatient rehabilitation facility and ⬆️ SNF utilization, ⬇️ home-time, but similar mortality Rural-Urban Disparity in Postacute Care and 1-Year Outcomes After Ischemic Stroke | Stroke ahajournals.org/doi/10.1161/…

Rural-Urban Disparity in Postacute Care and 1-Year Outcomes After Ischemic Stroke | Stroke

BACKGROUND: Rural residents have been experiencing higher stroke mortality than urban residents, and the gap has widened. Disparity in postacute care after stroke may increase the rural-urban gaps of...

ahajournals.org
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Gregg Fonarow MD@gcfmdMay 25
In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia | New England Journal of Medicine nejm.org/doi/full/10.1056/NE… @kewatson

In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia | NEJM

Persons carrying loss-of-function variants of proprotein convertase subtilisin–kexin type 9 (PCSK9) have reduced levels of low-density lipoprotein (LDL) cholesterol and fewer atherosclerotic cardio...

nejm.org
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Robert W. Yeh@rwyehMay 20
Excited to share two papers that we hope will give readers a framework for reading and conducting observational studies that are intended to compare treatments. First, a systematic approarch for comparing cardiovascular devices using observational data. ahajournals.org/doi/10.1161/…

Evaluating Cardiovascular Devices Using Observational Analyses | Circulation

It has long been accepted that observational analyses have an important role in evaluating use patterns and assessing the safety of different treatments, including cardiovascular devices, in clinical...

ahajournals.org
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Gregg Fonarow MD@gcfmdMay 18
In-Hospital Stroke Quality and Outcomes in the Mechanical Thrombectomy Era: Get With The Guidelines-Stroke, 2016 to 2023 | Stroke ahajournals.org/doi/10.1161/… @American_Stroke @StrokeAHA_ASA @AHAScience @AHA_Research #GWTG @brianmacgrory @ShumeiManMD

In-Hospital Stroke Quality and Outcomes in the Mechanical Thrombectomy Era: Get With The Guidelin...

BACKGROUND: In-hospital stroke is associated with delayed recognition and worse outcomes compared with community-onset stroke. Contemporary national data in the mechanical thrombectomy (MT) era are...

ahajournals.org
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Brian Mac Grory retweeted
Gregg Fonarow MD@gcfmdMay 1
Stroke Month 2026 During the first 20 years, Get With The Guidelines-Stroke participation was associated with sustained improvement in evidence-based care and outcomes for ~8 million patients with stroke and TIA in the US doi.org/10.1161/strokeaha.12…
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Brian Mac Grory retweeted
Steve Greene@SJGreene_mdJan 29
#QuadTherapy for #HFrEF is essential But is it enough? Even when prescribed 4 pillars, patients w/ HFrEF face very high residual risk of death & HF🏥 🚨New #GWTG_HF data putting HFrEF risk in perspective. @gcfmd @JavedButler1 @DukeHFDoc @JAMACardio jamanetwork.com/journals/jam…
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Brian Mac Grory retweeted
Gregg Fonarow MD@gcfmdJan 20
HF Care Differs Among Asian Subgroups in the US tctmd.com/news/hf-care-diffe… @NilayShahMDMPH @AHAScience @JACCJournals #GWTG

HF Care Differs Among Asian Subgroups in the US

The results make the case that it isn’t prudent to lump various Asian ethnicities together when trying to gauge care quality.

tctmd.com
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Gregg Fonarow MD@gcfmd30 Dec 2025
Delayed hospital arrivals are more prevalent among Asian, Black, and Hispanic patients, but EMS transportation times are shorter Race‐ and Ethnicity‐Specific Hospital Arrival and EMS Activation Times by US State for Ischemic Stroke | JAHA ahajournals.org/doi/10.1161/… @AHAScience

Race‐ and Ethnicity‐Specific Hospital Arrival and Emergency Medicine Service Activation Times by US...

ahajournals.org
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Brian Mac Grory retweeted
Circ: PHO@CircOutcomes19 Dec 2025
The AHA Target Stroke Phase III (TSIII) Program enhances timely EVT care @brianmacgrory @DCRInews @gcfmd @HeartNews @Braindoc_MGH @k_sauser @mayank_G0 @AshuPJadhav @VCI_EricSmith @AmeerEHassan @Akboehme @ASouthStrokeDoc @CerebrovascLab @JayBLusk ahajrnls.org/3Y8KQvU
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Brian Mac Grory retweeted
Gregg Fonarow MD@gcfmd20 Oct 2025
Association of Component Strategies of the Target Stroke Phase 3 Nationwide Quality Improvement Program With Accelerated Door-to-Puncture and Door-In-Door-Out Times for Ischemic Stroke Endovascular Thrombectomy in the United States ahajournals.org/doi/10.1161/… @AHAScience @DCRINews

Association of Component Strategies of the Target Stroke Phase 3 Nationwide Quality Improvement...

BACKGROUND: The Target Stroke Phase III program is a national quality improvement initiative led by the American Heart Association, which sought to improve the quality of care for patients with acute...

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📣@DukeMedSchool seeks a nationally recognized #anesthesiologist for chair of a top ranked department, Duke Anesthesiology. This is a unique opportunity to lead a renowned team known for excellence in patient care, research and education. 🔗Apply by 10/27: tinyurl.com/chairsearch
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Should dual energy CT head be offered at every comprehensive stroke center? I think so. Here's how it can change management (🧵1/3). 60s male presents after fall with altered mental status. Initial non-contrast CT head reveals a left frontal lobe ischemic infarct:
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Here is a concrete example where overcalling IIH can negatively affect patient care. Late teens patient with complex medical history presenting with headaches. Empty sella and prominent optic nerve fluid? How would you call it?
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