Neurointensivist investigating quantitative imaging markers of brain injury

Joined January 2011
I founded BEACON-Neuro.AI a month ago to enhance decision-making after stroke. Our beachhead product BeaconPredict provides precise prediction of which patients will develop malignant brain edema. It was just awarded Breakthrough Device Designation by the FDA.
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BeaconPredict, an AI-enabled tool designed to predict dangerous brain swelling after stroke, has received FDA Breakthrough Device designation. The tool was developed from research led by Rajat Dhar, MD. bit.ly/4w7yZxr
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Congratulations to Baback Arshi, MD, who received the Barnes-Jewish Hopsital Connect Award! His compassionate willingness to go above and beyond have made a lasting impact on patients and families. One family shared that Arshi doesn’t just treat patients, he treats people.
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Raj Dhar retweeted
My book is out. 𝘼𝙧𝙩𝙞𝙛𝙞𝙘𝙞𝙖𝙡 𝙄𝙣𝙩𝙚𝙡𝙡𝙞𝙜𝙚𝙣𝙘𝙚, 𝙉𝙖𝙩𝙪𝙧𝙖𝙡 𝙍𝙚𝙨𝙞𝙨𝙩𝙖𝙣𝙘𝙚 is a book about why healthcare institutions absorb capable technology and produce almost no change amzn.eu/d/09KAhpIs
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99%. That's how accurately BeaconPredict identifies stroke patients who need emergency brain surgery to relieve pressure from swelling. It's the first technology of its kind to give clinicians this level of certainty. Read more: bit.ly/4bxVyDd
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Du et al: Integrating Brain Imaging Volumetrics and Quantitative Pupillometry for Predicting Neurologic Deterioration after Large Hemispheric Stroke Link: link.springer.com/article/10… @neurocritical #neurocritcare
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The special issue on Genomics and Multi-Omics to Accelerate Stroke Research and Discovery in @_JCBFM was just released online. Lots of great articles, guest edited by myself in conjunction with @JinMooLee1 @WashUNeurology @strokegenomics journals.sagepub.com/toc/JCB…
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Exciting new research on SAH brain injury neuroprotection! 🧠✨ A recent randomized controlled trial shows that noninvasive transauricular vagus nerve stimulation (taVNS) can significantly improve outcomes for patients recovering from a subarachnoid hemorrhage (SAH). Key findings: 📉 taVNS significantly reduces key inflammatory cytokines (TNF-α and IL-6) in both blood plasma and cerebrospinal fluid. 🧠 The therapy reduces the rate of radiographic cerebral vasospasm, helping blood vessels return to normal caliber more rapidly. 🏥 Patients receiving taVNS demonstrated higher rates of favorable functional outcomes and a significantly lower rate of discharge to a skilled nursing facility or hospice. This represents a highly promising, low-risk bioelectric approach to neuro-immunomodulation in the ICU! ⚡👂 Source: Huguenard AL, Tan G, Rivet DJ, et al. Auricular vagus nerve stimulation for mitigation of inflammation and vasospasm in subarachnoid hemorrhage: a single-institution randomized controlled trial. J Neurosurg. 2025;142:1720-1731. thejns.org/doi/abs/10.3171/2…
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HOPE trial at #ESOC2026 🚨 Tailoring systolic BP to recanalisation status after EVT improves 90-day outcomes in acute ischemic stroke. Findings: •mRS 0–2: 60.0% vs 46.7%. •Hemorrhage: 22.3% vs 31.6%. •Mortality: 15% both. •Supports individualised BP post-thrombectomy.
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This is one of the most consequential positions to shape the future of #Neuroscience research and we need a strong, visionary leader to take the helm at @NIH_NINDS ✅ #NeuroTwitter
The @NIH, the world’s premier biomedical research institution, is seeking applications from exceptional candidates for the exciting position of Director, @NIH_NINDS. Learn more and apply: hubs.la/Q049_NtJ0 #NeuroTwitter
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🚨We review the role of AI-based imaging tools in stroke care, focusing on automated detection of imaging abnormalities & emerging tools that provide quantitative imaging biomarkers to support treatment decisions @SpringerNature : link.springer.com/article/10… Led by @barakhanov!
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ICYMI: #ISC26 Stroke Early Career Debate Recap: In this #BloggingStroke post, Kristina A. Rankine shares highlights from this session on open vs closed ICU models in stroke care. ahajournals.org/do/10.1161/b… @sauravmed @LBGoldsteinMD
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#FlashbackFriday ! 🧬🧠Study identifies new genes and pathways shared between cerebrovascular diseases and neurodegenerative diseases Read more below!👇 journals.sagepub.com/doi/ful…
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Our editorial on how genomics and multi-omics can accelerate scientific discovery across stroke research and advance new drug discovery; an introduction to an upcoming special issue for @_JCBFM - with excellent review and original articles journals.sagepub.com/doi/epd…
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Get ready for this. These Chinese investigators report a cohort of 121 malignant MCA infarction patients age >60, 47 of whom underwent drill-assisted sterotactic aspiration of the infarcted tissue from 24-72 hrs after onset. Check out the CT images and the 70 mL of nectrotic brain tissue in the image below to give you an idera of what they were doing. Retrospective, not randomized -- but the results were great. Herniation: 47% vs 9% Death: 65% vs 9% Favorable mRS (0-3): 3% vs 26% Not only #curingcoma –– cheating death. pmc.ncbi.nlm.nih.gov/article…
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