Small & mid-cap biotech | Special situations | Off-the-beaten-path ideas. Staunch believer in inefficient markets. Occasional beneficiary of them.

Cambridge, MA
Joined May 2009
$MRNA must die for the rest of $XBI to live
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Dana Street Capital retweeted
Small Cap stocks don’t even try to go up anymore. They just look at you like this.
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If $NKTR and $ABVX price action has told us one thing it's that (bad/mediocre drugs + competent management team) >>> (good/great drugs + shit management team). Howard and MDG are both complete dolts & even stumbling into blockbuster molecules might not be enough to save them + their shareholders
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If you think you're having a bad week I promise you it's not as bad as Caligan's $LQDA $ABVX
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how are bonds not seriously breaking stuff rn??
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degenerate thought exercise... but where would $ORCL trade if uncle Larry sells Donald i.e, USG a sliver of the company ala $INTC as another way to 'secure the domestic supply chain' for AI?
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Andddddd we’re off….
Prediction: $KOD pre-announces Monday AM data after close today. Shorts scramble to cover / chasers chase it higher A/H as everyone anticipates some ground breaking data. Disappoints on Monday and stock is down 20% - very similar to $OCUL earlier in year
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Prediction: $KOD pre-announces Monday AM data after close today. Shorts scramble to cover / chasers chase it higher A/H as everyone anticipates some ground breaking data. Disappoints on Monday and stock is down 20% - very similar to $OCUL earlier in year
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$NKTR longs celebrating their big court victory against $LLY 😂
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I cannot believe $TLT is about to see a 7 handle and market is still at/near ATHs - no wonder you see stuff breaking below the surface. We’ve entered the twilight zone here
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MORGAN STANLEY ACCIDENTALLY LEAKS 100+ DEAL PIPELINE A Morgan Stanley employee mistakenly emailed an internal document detailing more than 100 investment-banking deals being pitched or monitored across Asia and other regions. The list reportedly included potential IPOs, private-equity backers, pension funds and paused projects. Morgan Stanley said it promptly addressed the inadvertent disclosure and is engaging with relevant parties.
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Given AI-Bio theme being one of the hottest thematic sectors in the market and a major focus of Anthropic going forward, where would private markets be pricing $DNA if it didn't carry 5 years of public market synbio baggage with it? My guess is $2-3BN CC @jrkelly
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My take on these names, which certainly are attractive down here is.. Why be a hero and try to guess the bottom in levered cyclicals when there will be PLENTY of money to be made on the turn? QXO and BLDR for example looked “cheap” a month ago and both have fell another 20-30% since then
Quick thought on stocks: I don't know what's happening over the next 1-4 quarters with interest rates or housing construction, but there are a ton of construction/housing supply companies with great market positions that seem to be selling for a lot less than the discounted value of their future earnings. I own a lot of $QXO, but take a look at $BLDR or $HD or anyplace else in the supply chain. Even $POOL (which I kind of expect to get bought out). Many others in this category.
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$ROIV up an entire $LQDA on these Phase II PH-ILD results
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No details of the confirmatory trial in the PR was extremely bush league from $QURE management
$QURE classic buy the rumour sell the news. All announced today was expected; UK/FDA filings and the alignment on confirmatory trial laid out in Q2 call. IR communication could be better i.e. all in an 8K and not to a select group of brokers. Wise up Matt Kapusta. @uniQure_NV
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An $IREN fairytale in 3 parts… absolute joke these guys gave themselves a $1bn comp package the board signed off on lmao
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Feeling the same for all the reasons mentioned below. I’ve paired down portfolio to just a handful of names, mostly special sits with upcoming catalysts or perceived catalysts I think will lead to a re-rating regardless of macro: $QURE $CRTO $NN $ANAB $GROY and small spec lottos in $IVVD Q3 COVID readout and $CRVO 2H licensing deal The chop in this market is gunna be nasty from here on out
Replying to @cashiskinggg
I think the everything works regime is over Mkt not looking great Midterm seasonality Bessent trying (unsuccessfully) to intervene in yields Historic el nino projected massively inflationary to a food supply that Is already under duress SPR at all time lows Hormuz and black sea not letting much in Insurance mkt coming under scrutiny Open source models used more Public pressure on data centers etc etc Things will work but only certain things In my personal opinion
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Dana Street Capital retweeted
This is $MRNA asian play that I told people about a few months ago .: there were rumors of $PFE and $MRK trying to get something like this . Moderna is too expensive for BP. Not many biotechs ( hardly any ) have mRNA cancer vaccines. Everest has it in human trials with initial proof of concept ( inducing T cell responses and even one pt response ) They also have in vivo Car for auto immunity with in vivo mRNA
Next one on my list Everest medicine. $1952.HK
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Got both $LESL and $TENX very wrong this summer. Had sizable (5-10%) positions in both names at their peaks. No hedges and didn’t take anything off the table when was up 50-100% at some point in both. Leslie was case of trying to let a winner run after I initiated the position in 3s and not cutting bait soon enough when price action changed violently in the move from 12->7s, Tenex was outsized for a binary and should have been properly hedged. Can do nothing more than learn from these losers and keep head on straight, there’s so many great set ups in this market if you can stay vigilant and nimble, but you’re never gunna bat 1.000 as they say. Still cruising along YTD and 1Y in light of getting smacked around by both of these turds and excited about how portfolio is constructed into year end. Onwards and upwards!
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This was excellent.
I interviewed the CEO of an $850M drone stock supplying Anduril growing revenue 109%. $LPTH builds the "eye" of drones and counter-drone systems with its infrared optics. And it does it without dependence on China. Please enjoy my conversation with @skrubin, CEO of $LPTH
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