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Genmab Shares Hit Record After Cancer Drug Cuts Death Risk 50% — Genmab stock surged to a record high after results showed its cancer drug reduced the risk of death by 50%. The development puts the treatment in focus for investors and patients, though further details were not provided.

Emergency Declared At South Carolina Nuclear Site After Lab Fire — An emergency was declared at the Department of Energy’s Savannah River Site near Aiken, South Carolina, after a fire broke out in a laboratory. The available report does not specify the extent of damage or whether anyone was injured.

Trump Administration Moves To Allow Pharmacies To Make Popular Peptides — The Trump administration will allow pharmacies to make popular peptides, a shift that could widen access to the compounds. The move puts the administration’s approach to peptide availability in focus.

Fed Holds Rates Steady As Inflation Remains Elevated — The Federal Reserve left its benchmark interest rate unchanged, opting to wait for more economic data amid persistent inflation. The decision came ahead of the midterms.

Oracle Jumps As It Forecasts $225 Billion In Revenue By 2030 — Oracle shares rose 11% after the company projected $225 billion in fiscal 2030 revenue, implying average annual growth of 35%. The outlook and greater clarity on financing helped ease investor concerns about debt.

Fed Set To Hold Rates Ahead Of Midterms — The Federal Reserve is expected to keep interest rates steady in its final policy move before the midterm elections. The decision will draw close attention from markets and households watching the outlook for borrowing costs.

Trump Administration Offers $5 Billion in Loans for Nuclear Power Expansion — The Trump administration is offering Constellation Energy $5 billion in loans to expand nuclear capacity at eight power plants by 1.1 gigawatts. Much of the added power is expected to support data centers.

CISA Confirms PHP Vulnerabilities Are Being Exploited in Attacks — The U.S. cybersecurity agency says attackers are exploiting PHP2Shell vulnerabilities. The alert underscores the need for organizations using affected systems to address the flaws promptly.

Saudi Refinery Attack Fuels Fears of Wider Middle East Conflict — Oil prices climbed after an attack on Saudi Arabia’s Ras Tanura refinery heightened concerns about disruptions to global supply. The strike comes as tensions in the Middle East escalate.

Stellantis Reports $4.5 Billion Cash Drain As Turnaround Continues — Stellantis said it used up 4 billion euros ($4.5 billion) in cash in the third quarter as it pressed ahead with a $70 billion turnaround plan. The automaker is contending with mounting pressure as it navigates a shift to electric vehicles.

Trump Jokes $5,000 Checks Would Barely Cover Mar-a-Lago Meal — President Donald Trump joked that his promised $5,000 payments to Americans would not go far at Mar-a-Lago. He has said the payments would depend on Republicans winning control of Congress in November’s midterms.

GM Plans Lansing Investment For Future Hybrid Production — General Motors plans to invest in its Lansing Delta Township Assembly plant to prepare for future hybrid-electric vehicle production. The move signals a shift in the automaker’s strategy as it adapts its vehicle lineup.

Netanyahu Says Israel Has Chance To End Iran Threat — Prime Minister Benjamin Netanyahu said Israel has an “unprecedented and unique opportunity” to eliminate what he calls an existential threat from Iran. His remarks signal a continued focus on the Iran threat as the conflict unfolds.

Saar Says Israeli Vote Shows Emerging Jewish Majority — Foreign Minister Gideon Saar said a clear Jewish majority appeared to be emerging as results from Israel’s parliamentary election came in. The count is still taking shape, and no final outcome is reported in the available account.

GM Pivots From EV Push, Plans Hybrid SUVs — General Motors is shifting its strategy toward hybrid SUVs as it recalibrates its electric-vehicle plans. The move signals a change in the automaker’s approach to meeting demand and navigating the transition to lower-emission vehicles.

Grand Jury Rejects DOJ Bid To Indict Former Trump Aide Cassidy Hutchinson — A federal grand jury in Washington, D.C., rejected the Justice Department’s request to indict former White House aide Cassidy Hutchinson. The reported decision marks a setback for the department’s effort to bring a case against her.

Fed Meeting: Five Key Questions for Investors — Markets are watching the Federal Reserve’s next meeting for signals on the path of interest rates. The decision and policymakers’ commentary could shape expectations for borrowing costs and financial markets.

Trump’s Manufacturing Revival Faces A Midterm-Era Data Test — President Donald Trump has promised to bring factory production back to the United States, but the latest data will show whether those pledges are translating into growth. The issue is emerging as a key test of the administration’s economic record ahead of the midterms.

Anduril And Qualcomm Launch BlueChip, A U.S.-Made Laptop — Anduril founder Palmer Luckey says the new BlueChip laptop will be made in the United States, with production extending beyond final assembly. The effort reflects a push to rebuild domestic computer manufacturing.

Nvidia Takes $3 Billion Stake In Meta As Chip Rivalry Intensifies — Nvidia is taking a $3 billion equity stake in Meta, deepening ties between the AI chipmaker and the social media giant. The move comes as Meta pursues major financing for its AI infrastructure and Broadcom also figures in the chip race.