What would we imagine slow deterioration of cognitive processing and executive functioning? I think it looks like now.
What
@drseanmullen doesn't mention is that some people suffer a permanent and noticeable decline from a single infection, but they seem to be the exception.
Let’s say that SARS-CoV-2 caused some degree of cognitive dysfunction in everyone infected…and each infection made things a little worse.
Now suppose infections produced cumulative injury preferentially in periventricular/deep white matter and the small-vessel territories surrounding the ventricles.
What functions would be most affected?
People might still know things. Expertise, accumulated semantic knowledge, verbal fluency, and crystallized intelligence could remain remarkably well preserved.
The impairment could instead lie in using that knowledge efficiently under complexity…processing information quickly, sustaining and dividing attention, inhibiting competing responses, switching between mental sets, holding multiple considerations in mind, and flexibly updating conclusions.
That matters because this kind of dysfunction may not announce itself as dramatic memory loss or obvious global cognitive impairment.
The population-level signal might instead emerge in reaction-time distributions, processing speed, interference control, set shifting, sustained/divided attention, working memory, and demanding multitask paradigms…domains particularly vulnerable in vascular white-matter disease.
Damage enough strategic white-matter connections and you don’t necessarily destroy the cortical regions containing someone’s knowledge.
Nope.
You degrade the communication architecture connecting otherwise functional regions.
That’s why “disconnection” is such a useful model.
The nodes can remain remarkably capable while communication among them becomes progressively less efficient.
So…
What would a society look like if expertise remained visible, but the cognitive machinery required to deploy it flexibly under complexity was gradually deteriorating?
Here’s where I stop describing the thought experiment.
Because I think about this constantly now.
I watch people struggle to sustain attention for five minutes.
Ask someone to incorporate something genuinely new into a workflow they’ve performed for years.
Ask people to hold several competing explanations in mind simultaneously.
Ask them to entertain a hypothetical without immediately collapsing it into what they already believe.
Watch what happens.
None of those observations proves SARS-CoV-2 caused what you’re seeing. Of course it doesn’t.
But the part I find difficult to shake..
If population-level executive function and processing speed really were slowly deteriorating, what exactly do we imagine it would look like?
Because I don’t think it would look like everyone suddenly forgetting their names.
I think it might look disturbingly ordinary.