@basicchemist

Now a post-doc at BU with the Allen Lab. Structural biology and enzymology. PhD from the Booker Lab at PSU.

Joined February 2017
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Data collection workshop @CryoEM_PNCC
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Happy Valentine’s Day.
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So perfect it doesn’t look right.
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Small, but mighty
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This protein reacts well under the stress of an impending beam time.
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These tiny crystals are only carrying all of my hopes and dreams.
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Patience. And a little luck.
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Proteins know when you're on a deadline and then choose not to purify.
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Looking up at giants @CryoEM_PNCC
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A great start to a week at @CryoEM_PNCC !
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First postdoc paper! Much thanks to Karen! authors.elsevier.com/a/1gME5…
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Crystal trays set up before break are always an exercise in hoping.
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Staring at reactions does not, in fact, make them go faster.
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As part of #BUPDA @BU_Tweets, we organized a post doc mini-retreat on the beautiful #CharlesRiverCampus with interactive talks from @LaurenACelano and @EswaraPallavi on post doc training and creating your online presence! #NationalPostdocAppreciationWeek
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I think crystals know when you don't have synchrotron time scheduled for two months.
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I hope everyone sleeps well tonight, except for reviewer 2.
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Hayley Knox, PhD retweeted
Paula Welander@PaulaWelander27 Jul 2022
Beautiful structural study from @BookerMan_PSU and colleagues on the mechanistic details of GDGT formation resolving a decades long question - the substrate is fully saturated!!😮microbial biochemistry is so wild... nature.com/articles/s41586-0…

Discovery, structure and mechanism of a tetraether lipid synthase

Nature - In Methanocaldococcus jannaschii, a radical S-adenosylmethionine enzyme catalyses the formation of the biphytanyl chain.

nature.com
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I thought the worst thing was getting salt diffraction during screening. It is actually getting no diffraction, protein or salt, from beautiful crystals.
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It’s important to let your dewar stop and smell the flowers before going to the synchrotron.
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Just a dewar on its commute.
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