Inmunologist. Opinions my own.
Joined February 2020
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Long-Term Effectiveness and Discontinuation of Dupilumab in Patients With Atopic Dermatitis jamanetwork.com/journals/jam…
Variables in allergens causing FDEIA vs those that independently cause anaphylaxis without cofactors #EAACI2024
SpIgE tends to be lower in LTP sensitised patients with exercise-induced symptoms #EAACI2024
Lipid transfer proteins an important cause of FDEIA - initially recognised in Italy, southern Europe but now more widely seen #EAACI2024
Multiple potential co-factors - including PPI use! - can increase risk of a systemic allergic reaction to a labile food allergen #EAACI2024 @EAACI_HQ
Simple but really critical points about use of specific IgE (and all in vitro tests) for dx of food allergy. Importance of knowing your test platform and clinical correlation - Thomas Eiwegger #EAACI2024 @EAACI_HQ
Genuine bumble bee allergy: must treat with bumble bee VIT, honey bee VIT ineffective #EAACI2024
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IgE mediated reactions to haematophagus insects uncommon, specific IgE does not perform well, can do sting challenge if very motivated! #EAACI2024
Higher risk of ongoing reactions following cessation of VIT with honeybee vs wasp. Better to assess duration of VIT on case by case basis as opposed to standard 5 year for all #EAACI2024
Safe and effective to increase dose interval for VIT over time, more data needed for mastocytosis however #EAACI2024 @EAACI_HQ
Positive Phase III results for donidalorsen (anti sense oligonucleotide) for long term prophylaxis in HAE announced at EAACI today #EAACI2024 nejm.org/doi/full/10.1056/NE…
CS hypersensitivity: patients may tolerate via one route but react via another and vice versa #EAACI2024
Consider excipients eg carboxymethylcellulose in immediate hypersensitivity to depot CS #EAACI2024
