🇨🇦 Rheumatologist, scientist, dad, he/him, advocate for #healthcare, #rheumatology, #research, #osteoarthritis. Tweets my own

London, Canada
Joined March 2011
🚨Standard scRNA-seq often excludes cells with high mitochondrial RNA content (pMT).🚨 Work by Tran et al. investigates how exclusion of high-pMT cells affects the transcriptional landscape of knee OA synovium and explores their role in disease. 🔗sciencedirect.com/science/ar…
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📢 “When we first started to see the big effects of these blockbuster #GLP1 drugs, people were talking about weight loss from Hollywood to regular people’s homes,” said Dr. Tom Appleton @appletonlab. Read the Healio Exclusive @HealioRheum 👇 vist.ly/4tb3a
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Tom Appleton retweeted
🎙️NEW #AroundtheRheum podcast episode! Co-hosts Drs. Daniel Ennis & @Janetbirdope chat with Dr. Sherry Rohekar about the new Canadian Living Guideline for the Management of Axial Spondyloarthritis! You won't want to miss it! Listen now🔈podcasts.apple.com/ca/podcas…
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Tom Appleton retweeted
The Early-stage Symptomatic Knee Osteoarthritis (EsSKOA) Initiative @oarsinewsis seeking datasets for analyses Let us know if you have a dataset with >100 adults with knee symptoms & data on identified candidate items redcap.utoronto.ca/surveys/?…
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Interested in helping the early-stage symptomatic knee #osteoarthritis (#EsSKOA) classification criteria development @OARSInews initiative? Participate in this survey: redcap.utoronto.ca/surveys/?…
Early-stage symptomatic knee #osteoarthritis (#EsSKOA)— an @OARSInews initiative expertly presented by @curious_zan, @Lauren_King_, & @rheum_cat (and expert handling of Q&A!) #OARSI2024
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17 #CRArthritis interviews. 1 more #ASM24 day to go! Today's interviews: bit.ly/CRArthritis2024-Day3 Tomorrow's lineup: Drs Steven Katz, Jill Hall, Meghan Pancucci, @appletonlab, @maryadevera, @annasamson_, @MichaelKuluva, @kabeattie, @m_batthish, @meganthomas829 & @KT_trainee!
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Apply now using the link in our bio! Take a Pain Check is excited to announce our new scholarship, STEM Without Limits Take a Pain Check Scholarship! #takeapaincheck #scholarship #applynow #university #canada #opportunity #apply #scholarshipSTEM #STEM #french
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Check this out & pls share! We’re looking to hire a research asst to work on a variety rheumatic and MSK disease studies. We are a highly productive, energetic, and fun group! 💃🏽
Are you (or you know of) a Research Asst looking for a new opportunity in clinical research involving NIH-funded large cohorts, clinical trials, biorepository, opportunity for scholarly activity, & helping people w/ #rheumatic diseases? We're hiring! linkedin.com/jobs/view/34597…
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Is AI the Future of Care in Rheumatology? Tune in on Friday, Feb 10th at 12:30pm in the Quebec City Convention Centre to hear more from Dr. Lily Lim, Dr. Tom Appleton and myself. @CRASCRRheum @appletonlab
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New content online! Understanding synovial cell diversity in post-traumatic OA dlvr.it/SdNGLP
Tom Appleton retweeted
#ACR21 OA community hub events for TODAY 12:00-1:30pm ET OA Study Group: Classification criteria for early stage knee OA - it’s about time(ing)! With @UofTDoMChair @appletonlab Stefan Lohmander & Armaghan Mahmoudian
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Replying to @ACRSimpleTasks
Hey @ACRSimpleTasks -- this needs updating! #OA should not be described as 'wear and tear'. And management options in the link are not all evidence-based, and in fact, contradict some of the @ACRheum + @ArthritisFdn 2019 osteoarthritis treatment guideline! onlinelibrary.wiley.com/doi/…
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More than 4 million Canadians, or about 1 in every 7 adults, have #osteoarthritis. Special Report: The Burden of Osteoarthritis in Canada @ArthritisSoc 🇨🇦arthritis.ca/getmedia/36cbff…
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Really happy that Ontario is now allowing for outdoor activities during this 3rd wave with playgrounds etc open. This is a smart move, enables physical & mental health, & is grounded in good science. Much appreciated. ...
Ontario’s enhanced restrictions were always intended to stop large gatherings where spread can happen. Our regulations will be amended to allow playgrounds but gatherings outside will still be enforced. Play outside safely. Parents keep your distance & wear masks if you can’t.
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Would love to see some representation from 🇨🇦 people living with arthritis. It’s is quick, clear and concise! Designed with people who have lived experience. @Arthritis_ARC @ACEJointHealth @jodiroxs @McCaigInstitute @boneandjointab @westernuBJI @BoneJointCanada
Knowledge helps people to make health choices. We want to find out what people know about hip and knee arthritis so that we can build and test better information. If you have knee or hip arthritis, please complete a brief (10 mins) survey: otago.au1.qualtrics.com/jfe/… @CentreforSEOA
Tom Appleton retweeted
Big news. Announcement of ORAL Surveillance. CV risk pts with RA randomized to tofacitinib 10 mg BID (stopped with more VTE). So remaining Tofa 5 mg bid vs TNFi: Etanercept or Adalimumab. MACE IR 0.91 v 0.73 in Tofa 5 v TNF. Non inferiority NOT met ie MACE more in TOFA @RheumNow
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Great job by Jim Lewis talking about our surfactant trial on CTV your morning (while also, subliminally, applying for a job at Hockey Night in Canada).
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Wow! Further support for #PhysicalTherapy in knee #osteoarthritis, with this RCT demonstrating benefit over i.a. glucocorticoid injection. Congrats to @danrhon. @OARSInews @ACRheum nejm.org/doi/full/10.1056/NE…
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Tom Appleton retweeted
Why Hoarding Of Hydroxychloroquine Needs To Stop bit.ly/2JbdMwT