@anu_iris

Clinician Scientist. AI & Multi-omics. Biochemistry. Cancer Biology & Therapeutics @Harvard #PrecisionOncology #SpaceBiology @University_of_Malta

 India
Joined December 2018
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155Media
Fabulous moments! Humbled beyond words... @kaelin_lab and @DrSarcoma at @HarvardClub374
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🔥Hot off the press! First project in #Malta with @joseph_borg_ "Ionizing radiation-induced repair foci identification using deep convolutional neural networks" AI-based detection of DNA damage foci [IRIF] #DeepLearning #RadiationOncology #DigitalPathology
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🆕️Brilliant findings @PeterLyLab Horizontal human DNA transfer via nanotube connections Transferred DNA fragments confer heritable phenotypic traits to recipient cells #cancer DOI: 10.1016/j.cell.2026.04.041 @CellCellPress – at New York, USA
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Admirable work from Brazil🔥 Water & #p53: Functional flexibility at the expense of stability [One of my favourite topics in #oncobiochemistry] Frustration analysis reveals evolutionary conservation #cancer #chemistry #TP53 #mutation doi.org/10.1038/s42004-026-0…
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Precancerous niches as gatekeepers of tumor initiation dlvr.it/TSbv10
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This is a global issue for both Cisplatin and carboplatin .. @ChandrakanthMv needs to be highlighted … affecting so many pts @AyushmanNHA @CancerGridIndia @cspramesh @ASCO @DrSanjayPopat @myESMO … not an expensive drug so industry not bothered. @PMOIndia @JPNadda @ICMRDELHI @jrgralow @drkiwicj
MV Chandrakanth
@ChandrakanthMvMay 14
• Platinum chemotherapy shortage in India is becoming a major oncology challenge • Cisplatin & carboplatin are backbone drugs across many cancers • The issue is not just “drug availability” → raw material crisis → pricing pressure → manufacturing economics → supply-chain disruption • Real-world impact: → treatment delays → dose modifications → regimen changes → inventory pressure • Quick visual summary of: ✓ What is happening ✓ Why it is happening ✓ Clinical implications ✓ Possible solutions Would like to hear how different centres are managing this situation. #Oncology #CancerCare #DrugShortage #Cisplatin #Carboplatin #Chemotherapy #OncTwitter #MedTwitter #MVOnco
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⛔️First case reported: 13-month-old boy treated with #genetherapy for #HurlerSyndrome develops tumor at age 5 post adeno-associated viral genome integration resulting in AAV-PLAG1 transcript in brain cells. #biochemistry #cancer #MPS1 @NEJM
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#TumorBoardTuesday ⌛️1y ago we learned of a major📈in the cure for early stage gastric cancer 📢Join us Tuesday, 05-12-26 at 8PM ET as @SunnieSKim & @aprilchoi_md 🗣️updates to the MATTERHORN trial & Tx for early stage #gastriccancer RT and bring others into the discussion‼️
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Interesting! nature.com/articles/d41586-0… Cohort: 12.5m researchers Experienced researchers are less likely to produce ‘disruptive’/'novel' science Nostalgia effect: As careers progress, scientists are more likely to cite older papers than newer ones. #research
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First PROTAC gains FDA approval, bolstering targeted protein degradation and induced proximity ambitions nature.com/articles/d41573-0… Arvinas and Pfizer’s oestrogen receptor degrader vepdegestrant has secured approval for a subset of patients with advanced or metastatic breast cancer
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Wonderful work @UMichMedSchool ✅️Variant function assessment #VUS #cancer #MAVE Saturation mutagenesis + DNA repair reporter assay to show Functional enzyme activity of MUTYH 》》 Base Excision Repair🔥 DOI: 10.1016/j.ajhg.2025.07.005 @CellCellPress
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Biology's dwarf planets! TransCODE Consortium finds #darkprotein microproteins & peptideins Translational products with unknown function from ncORFs nature.com/articles/s41586-0… #cancer #proteomics @AfshinBeheshti @joseph_borg_ @mason_lab @RyanTScott
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#AACR26 Closing Plenary: excellent summary by @UTMDAnderson #ClinicalTrials to look forward to! @AACR
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#AACR26 Closing Plenary @AACR @YaleCancer TOP CONCEPTS Proximity-inducing: Degraders Docked Deliveries: ADCs Cellular Therapy advancements Personalized vaccines MRD
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#AACR26 Day6 Innovative therpeutic modalities: ADCs & TIL TIL: Blinatumomab + Chemotherapy @AACR @ZymeworksInc @NKI_nl
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#AACR26 Immensely happy to showcase our work!!! 🎗 👩‍🚀 @AACR @mason_lab @AfshinBeheshti @RyanTScott @joseph_borg_ @KurtSpeeten @ josefborg @KJangkeun @ tricialarose @YJanjigianMD @NASAGeneLab @PittTweet @WeillCornell @UMmalta @Spaceomix @uhasselt
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#AACR26 Day 5 Plenary Session: #MutationalSignatures Its always a pleasure to listen to Dr Ludmil Alexandrov! ■Investigating causality ■Early detection ■Fingerprint of cancer @AACR @UCSDHealth @SerenaNikZainal – at San Diego, CA
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This was for me the best part of #AACR26!💛 Meeting Dr @YJanjigianMD again and talking about work & much more! Thank you for your unwavering support over the years💫 @MSKCancerCenter @AACR @ESMO @Spaceomix #oncology #cancerresearch #Immunotherapy – at San Diego, CA
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#AACR26 🔥Synthetic Lethality and DNA Damage Repair Good sessions from @DanaFarber @UofCalifornia @UMassChan This will always be a challenging path as we intend to target evolutionarily conserved cellular ecosystems. Also follow @kaelin_lab for SL! @AACR – at San Diego, CA
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#AACR26 has arranged an excellent interactive platform with Editors & the team of leading @AACR journals One-to-one interactions directed towards honing quality research for superior showcasing The @CD_AACR Team with @ElizSMcKenna at Booth 3537 here was awesome! – at San Diego, CA
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#AACR26 Plenary Session Day 4 #AI in Cancer Research All about BIOMNI from @Stanford @AACR – at San Diego, CA
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