@anikasinga

Consultant Virologist at UKHSA. Respiratory and enteric viruses / transmission / human challenge / public health.

Joined January 2010
  • Tweets248
  • Following602
  • Followers208
4Media
Listen to a Lancet podcast where we discuss our @LancetMicrobe #humanchallenge paper here: buzzsprout.com/1794195/13024…
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Anika Singanayagam retweeted
FluTrackers.com@FluTrackers9 Oct 2024
US - California: CDPH statement - 3rd #H5N1 confirmed human case confirmed by the CDC. + 2 more possible cases identified with CDC tests pending. All are animal contact, mild symptoms. flutrackers.com/forum/forum/… h/t Commonground
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Doses of an experimental #Marburg vaccine — designed at the @NIH's Vaccine Research Center & being developed by @sabinvaccine — arrived in Rwanda on Saturday where a clinical trial will soon get underway. Photo: Sabin Institute statnews.com/2024/10/04/marb…
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theguardian.com/world/2024/o…

Bird flu outbreak kills dozens of tigers in Vietnam zoos

The H5N1 virus killed 47 tigers, three lions and a panther at the My Quynh safari park and the Vuon Xoai zoo, according to state media

theguardian.com
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cidrap.umn.edu/avian-influen…

H5N1 infects second farm worker in California as feds bolster vaccine supply

cidrap.umn.edu
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Anika Singanayagam retweeted
Options2024@options20242 Oct 2024
Replying to @mvankerkhove
@mvankerkhove of @WHO urging for evidence driven policy, equitable access to safe and effective vaccines, building Pandemic Influenza Preparedness (PIP) strategy, and platforms to facilitate sharing of key reagents
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Anika Singanayagam retweeted
The Pathologist@pathologistmag28 Sep 2024
Do we need more women in #pathology mentoring and leadership? Ann Gronowski believes we do, and here’s why 💭 bit.ly/3vuIJYr
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An important study by F. Eun-Hyung Lee's team shows that long lived plasma cells (the source of long-term circulating antibodies) fail to establish after mRNA vaccination (even combined with SARS-CoV-2 infection). 🧵 (1/) nature.com/articles/s41591-0…

SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compar...

Nature Medicine - The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in...

nature.com
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Nice article
The Pathologist@pathologistmag27 Sep 2024
Are diagnostics up to scratch in tackling #polio and other #enteroviruses? Read more: bit.ly/3LUawWR #InfectiousDisease #DiagnosticsDevelopment #VirusResearch
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Amazing, quick work! Would like to hear what is happening in NA/2SBS also. A160T restores a glycosylation site that could affect HA:NA balance e.g. doi.org/10.1371/journal.ppat…

Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compens...

Author summary Influenza pandemics can have devastating effects as was dramatically demonstrated by the so-called Spanish flu in 1918. Such pandemics are caused by animal influenza A viruses (IAVs)...

journals.plos.org
Bloom Lab
@jbloom_lab15 Sep 2024
Here is analysis of HA mutations in H5 influenza case in Missouri resident without known contact w animals or raw milk. TLDR: there is one HA mutation that strongly affects antigenicity, and another that merits some further study.
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Picked up via routine national influenza surveillance 💪
CDC Flu
@CDCFlu6 Sep 2024
CDC confirmed a human case of H5 bird flu in Missouri in a person who has fully recovered. This is the 14th case in the United States in 2024. An investigation into the potential exposure is ongoing, but the public risk assessment remains low at this time. Read more: bit.ly/47lFRvx
A chicken sitting on the ground next to another partially visible chicken. “Bird Flu Update” is written in white letters on a blue background. in the top left corner. The CDC-branded logo is on the bottom right corner while “cdc.gov/bird-flu” written in white on a purple background is in the bottom left corner.

ALT A chicken sitting on the ground next to another partially visible chicken. “Bird Flu Update” is written in white letters on a blue background. in the top left corner. The CDC-branded logo is on the bottom right corner while “cdc.gov/bird-flu” written in white on a purple background is in the bottom left corner.

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Anika Singanayagam retweeted
Imperial Medicine@ImperialMed28 Aug 2024
Why are some people volunteering to be infected with diseases? Dr @anikasinga from @ImperialInfect shares preliminary insights and findings on the SARS-CoV-2 human challenge study with @BBCNews #COVID19 bbc.com/future/article/20240…

Why some people are volunteering to be infected with diseases

Scientists are turning to a controversial approach to test new vaccines and treatments by deliberately infecting volunteers with potentially deadly viruses, parasites and bacteria.

bbc.com
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Anika Singanayagam retweeted
CIDRAP@CIDRAP8 Aug 2024
Clinicians detail H5N1 infections in 2 Michigan farm workers One patient had conjunctivitis in one eye, and the other had longer lasting flulike symptoms. ow.ly/laZi50SUc1Y
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MSC has published its findings on the 2023 clinical academic survey, revealing an ageing workforce and continuing gender and ethnic imbalances in clinical academia. Press release: bit.ly/3vGqZJU Interactive tool: bit.ly/3JsxwMM
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3rd US #H5N1 #birdflu case, this one with respiratory symptoms. Farm worker in Michigan who wasn't wearing PPE. Said to be recovering. statnews.com/2024/05/30/bird…

A third U.S. farmworker infected with bird flu is the first to experience respiratory symptoms

Whereas the two earlier human cases reported this year experienced only conjunctivitis — known as pink eye — the Michigan worker experienced respiratory symptoms.

statnews.com
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Agree with all of this - great article in @NatureMedicine - "Why diversity is needed at every level of clinical trials, from participants to leaders" nature.com/articles/s41591-0…

Why diversity is needed at every level of clinical trials, from participants to leaders

Nature Medicine - Diversity in clinical trials must be accompanied by justice and equity, including benefits for underrepresented participants, in order to boost population health.

nature.com
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Anika Singanayagam retweeted
Secretary Tom Vilsack
@SecVilsack24 Apr 2024
To further protect the U.S. livestock industry from the threat posed by highly pathogenic H5N1 avian influenza, @USDA is sharing a number of actions that we are taking with our federal partners to help us get ahead of this disease and limit its spread. usda.gov/media/press-release…

USDA Actions to Protect Livestock Health From Highly Pathogenic H5N1 Avian Influenza

usda.gov
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science.org/content/article/…
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Anika Singanayagam retweeted
COVHIC002@Covhic002Trial10 Apr 2024
LAST CHANCE!📢 We are looking for healthy volunteers to take part in our COVID-19 Human Challenge study. If you are 18-30yrs, have been vaccinated against COVID-19 and in good health, visit: imperial.ac.uk/infectious-di…. You will be paid up to £4,500 for your time and inconvenience.
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Happy #InternationalWomensDay Pleased to have been featured in this #IWD2024 article @Inst_Infection
Imperial Department of Infectious Disease@ImperialInfect8 Mar 2024
Replying to @ImperialInfect
"Having equal representation of women and men in clinical trials is something healthcare professionals should strive for." Dr Anika Singanayagam (@anikasinga), PI forSARS-CoV-2 Human Challenge Study talks about the importance of representation in clinical trials.
Image of Dr Anika Singanayagam looking at the camera.

ALT Image of Dr Anika Singanayagam looking at the camera.

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"Having strong representation of women at the forefront of Infection research and decision-making – leading research grants, acting as PIs on clinical trials, and contributing to national advisory committees, is key to ensuring women’s health needs are given due attention.”
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