REMAP-CAP challenges individual-level thinking. Oseltamivir doesnt improve mortality in severe flu. Time for a blanket approach? or is that a step too far.. what if they have had two doses prior to coming to us, what about viral shedding and outbreaks in vulnerable grps.#ccr26

🚨 REMAP-CAP at #CCR26 tests what we thought was settled - early oseltamivir in severe influenza. 19.5-20.4% mortality with oseltamivir vs 13.7% without. Posterior probability of harm 98%+. Pattern repeats: multimodal supportive care, not pharmacological rescue. @ICNARC ‼️

#REMAPCAP wasn’t built in peacetime. It’s a factorial trial federation born when flu hit hard and we needed answers fast. Now, at #CCR26, the data on influenza is here (last minute). #CriticalCare #ICU

#TeleRehabTrial turning heads. Telehealth ICU rehab: vent days down by 6.2 days, hospital-free days up by 4.9, and a 7.6% reduction in 90-day mortality. The post-hoc decomposition shows most of that mortality gain came from ICU survival. Hard to ignore. #CCR26 #rehab #PICS

Right on… cornwalllive.com/whats-on/wh…

At the @FICMNews FICM Clinical Leads meeting. Looking at how we Lead with a systems approach. The importance of safety and the challenges to this by the current pressures on the NHS. The linked concerns of pressures and continued safe care.

#CCR22 #Rephilltrial pregnancy is a common exclusion criteria, it is often understandable, but not always. Does a reflexive exclusion cause harm, are we denuding the evidence base to inform and improve treatment decisions during pregnancy.

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