@allenlab

Official Twitter account of the Allen Lab at Boston University

Joined April 2010
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PGT enzymes catalyze the pathway that builds the sugar-rich protective coating on many cells. In a @PPPublishing review, Barbara Imperiali, @allenlab, and @Otoole4K discuss insights into two unique PGT superfamilies: bit.ly/3pXdqhJ
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#ACCEPTED - “The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases” first authored by @Otoole4K in collaboration with the Imperiali Lab at MIT! #BiochemSocTrans @PPPublishing @BUChemistry @MITBiology portlandpress.com/biochemsoc…
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PGTs promote the first membrane-committed step in complex glycoconjugate biosynthesis pathways by catalyzing the transfer of a phospho-sugar from a nucleoside diphospho-sugar to a membrane-resident polyprenol phosphate.
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Surprisingly, nature has evolved two superfamilies with distinct protein scaffolds to enact the same fundamental reaction through two different chemical mechanisms.
Congratulations to @kna6662 for being nominated into the first class of ASBMB Fellows!
ASBMB@ASBMB11 May 2021
Replying to @ASBMB
.@kna6662 is a founding member of our Women in Biochemistry & Molecular Biology Committee. asbmb.org/asbmb-today/policy… Her lab uses structural biology techniques to study enzyme evolution and substrate specificity, w/a longstanding focus on the haloalkanoate dehalogenase superfamily.
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The Allen Lab is back on Twitter after a 10+ year hiatus! Stay tuned to hear about our recent work and lab member accomplishments!
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Go Allen Lab! We're on Twitter!!
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