Plant genome evolution, TEs, epigenetics
University of Sussex, England
Joined December 2010
- Tweets239
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- Followers278
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Alexandros Bousios retweeted
CRISPR-mediated centromere fission generates neochromosomes with distorted meiotic inheritance in Arabidopsis biorxiv.org/content/10.64898… new preprint from us - includes changing the Arabidopsis karyotype from 5 -> 6 chromosomes using Cas9 & outcomes of 5/6 chromosome hybrid meiosis
Alexandros Bousios retweeted
Happy to have two preprints of the lab featured within the 1%
Read them:
Sex without crossovers mimics clonal reproduction in Rhynchospora tenuis
biorxiv.org/content/10.64898…
Pangenome analysis reveals the evolutionary dynamics of repeat-based holocentromeres
biorxiv.org/content/10.64898…
🎉 Meet The 1%.
QED Science evaluated 57,455 @biorxivpreprint life science preprints - blindly, at scale, and on the strength of the science itself.
Today, we’re celebrating the 574 manuscripts that rose to the top.
🏅 The 1%: the-one-percent.qedscience.c…
Good science deserves to be seen.
@openrxiv @cshperspectives
Alexandros Bousios retweeted
@marques_et_al Huge congratulations 🤩 two preprints in the top 1% is incredible! Excited to see this work getting the attention it deserves, and looking forward to reading more 🙌
Alexandros Bousios retweeted
🤩
@marques_et_al Huge congratulations 🤩 two preprints in the top 1% is incredible! Excited to see this work getting the attention it deserves, and looking forward to reading more 🙌
Alexandros Bousios retweeted
🌱EPIPLANT is live!
Registration is now open for the EPIPLANT 2026 conference (June 22–24).
We look forward to welcoming you to Nantes, France for an exciting conference on the epigenetics of photosynthetic organisms!
👉Details & registration: epiplant-2026.sciencesconf.o…
Alexandros Bousios retweeted
Huge pleasure for me and @abousios to finally get Dr @ozgendeniz_ from @QMUL @QMBCI down to @SussexLifeSci for the @BiochemBiomedUS seminar series.
Ozgen gave a fantastic overview of her incredible research into the role of transposable elements in KMT2A-r and DNMT3Amut AML.
Come join our lab in Sussex, UK for a PhD on TEs, on centromeres, on the genome ecosystem! Exciting times for TE:genome dynamics given the rate of T2T sequencing. Please circulate! findaphd.com/phds/project/ev…
Alexandros Bousios retweeted
Announcing on behalf of UK Genetics Society - a fabulous Anniversary Day celebration of Genetics in Edinburgh this 25th-26th June - register here: genetics.org.uk/events/anniv…
Alexandros Bousios retweeted
📢 Three new #bioRxiv preprints from our team on holocentric chromosomes.
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
Alexandros Bousios retweeted
The majority of plant DNA is essentially parasitic, encoding the message, 'make more of me.' And the vast majority of chromatin modification in plant genomes can be interpreting as saying, 'don't do that.' Genomes are shaped, in large measure, by this conversation. Huge if true.
Alexandros Bousios retweeted
Many of the most complex and useful functions in biology emerge at the scale of whole genomes.
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
Alexandros Bousios retweeted
Authors in this paper used 193 Darwin Tree of Life project reference genomes to study centromere architecture.
What is a #centromere? It's the region of a chromosome where the microtubules attach during cell division - key equipment!
Read more ⤵️
researchsquare.com/article/r…
ALT Zephyris at the English-language Wikipedia, CC BY-SA 3.0 <http://creativecommons.org/licenses/by-sa/3.0/>, via Wikimedia Commons
Our new preprint on somatic TE transposition in A. thaliana is out! It looks like TEs jump like crazy! Led by the amazing @ambreen_heena and with @genomeorglab biorxiv.org/content/10.1101/…
see Heena's post for a cool summary xitter.cf/ambreen_heena/status/1…
1/📢News from TE diary - Somatic transposition in Arabidopsis is more explosive than we imagined!
Thrilled to share our latest findings - TEs make new somatic insertions en masse, reshaping somatic genome🧬with surprising frequency
@abousios @genomeorglab
biorxiv.org/content/10.1101/…
Alexandros Bousios retweeted
1/📢News from TE diary - Somatic transposition in Arabidopsis is more explosive than we imagined!
Thrilled to share our latest findings - TEs make new somatic insertions en masse, reshaping somatic genome🧬with surprising frequency
@abousios @genomeorglab
biorxiv.org/content/10.1101/…
Alexandros Bousios retweeted
🚨New paper, now published in @Nature! Using pan-genetics across the Solanum genus🍅🥔🍆we reveal why gene duplications🧬are major contingencies in crop engineering. My postdoc work in the Lippman lab @CSHL, in collab. with @mike_schatz and many others! nature.com/articles/s41586-0…
Another piece to add in the emerging golden era of centromere research. Our review of centrophilic transposons in plants @AnnualReviews with @hendersi and @KakutaniTe annualreviews.org/content/jo…
Alexandros Bousios retweeted
Centrophilic Retrotransposons of Plant Genomes
annualreviews.org/content/jo… new @AnnualReviews from @abousios @KakutaniTe and myself on my favourite class of mobile genetic element
Alexandros Bousios retweeted
We have a research laboratory technician post available in my group - the role will support plant work, and molecular biology, associated with our research on centromeres.
jobs.cam.ac.uk/job/47342/
Beautiful collaboration led by Tetsuji Kakutani and Sayuri Tsukahara on unravelling the fine changes that can make a centrophobic TE become centrophilic and vice versa! The devil is in the details for these TEs. nature.com/articles/s41586-0…
